AFAP antibody

Catalog No. ABIN7111205

The Rabbit Polyclonal anti-AFAP antibody is suitable to detect AFAP in samples from Human, Mouse and Rat. It has been validated for WB, ELISA and IF.

Quick Overview for AFAP antibody (ABIN7111205)

Target: AFAP (AFAP1) (Actin Filament Associated Protein 1 (AFAP1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AFAP antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Product Details anti-AFAP Antibody

Purpose: AFAP1 antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: actin filament associated protein 1

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:5000, IF: 1:10-1:100

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for AFAP

Target: AFAP (AFAP1) (Actin Filament Associated Protein 1 (AFAP1))

Alternative Name: AFAP1

Background:

Synonyms: Actin filament-associated protein 1|110 kDa actin filament-associated protein (AFAP-110)|AFAP1|AFAP

Background: Can cross-link actin filaments into both network and bundle structures(By similarity). May modulate changes in actin filament integrity and induce lamellipodia formation. May function as an adapter molecule that links other proteins, such as SRC and PKC to the actin cytoskeleton. Seems to play a role in the development and progression of prostate adenocarcinoma by regulating cell-matrix adhesions and migration in the cancer cells.

Molecular Weight: 81 kDa, 110 kDa

Gene ID: 60312

UniProt: Q8N556