Actin-Like 6B Proteins (ACTL6B)

The protein encoded by ACTL6B is a member of a family of actin-related proteins (ARPs) which share significant amino acid sequence identity to conventional actins. Additionally we are shipping Actin-Like 6B Antibodies (58) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
ACTL6B 51412 O94805
ACTL6B 83766 Q99MR0
ACTL6B 288563 P86173
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Top Actin-Like 6B Proteins at antibodies-online.com

Showing 4 out of 4 products:

Catalog No. Origin Source Conjugate Images Quantity Delivery Price Details
Insect Cells Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg 50 Days
$6,749.58
Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg 50 Days
$6,749.58
Details
Yeast Rat His tag   1 mg 60 to 71 Days
$3,188.17
Details
Yeast Cow His tag   1 mg 60 to 71 Days
$3,188.17
Details

ACTL6B Proteins by Origin and Source

Origin Expressed in Conjugate
Human

Mouse (Murine)

Rat (Rattus)

More Proteins for Actin-Like 6B (ACTL6B) Interaction Partners

Human Actin-Like 6B (ACTL6B) interaction partners

  1. provide additional genetic and clinical data on three new cases that support the pathogenic role of ACTL6B gene mutation in a syndromic form of Developmental and epileptic encephalopathies.

  2. Missense Mutation in ACTL6B gene is associated with Neurodevelopmental Disorders.

  3. we identified BAF53b as a neuron-specific subunit of the chromatin remodeling BAF complexes.

  4. Data suggest that SWI/SNF complexes containing ArpN alpha might regulate certain genes involved in brain development and/or its function differently from SWI/SNF complexes containing ArpN beta/BAF53.

Mouse (Murine) Actin-Like 6B (ACTL6B) interaction partners

  1. Results show that deleting HDAC3 can ameliorate the impairments in both long-term memory and synaptic plasticity caused by BAF53b mutation. This suggests a dynamic interplay exists between histone acetylation/deacetylation and nucleosome remodeling mechanisms in the regulation of memory formation.

  2. This study demonstrated that Mutation of neuron-specific chromatin remodeling subunit BAF53b showed impairments in phosphorylation of synaptic cofilin, LTP, and memory.

  3. Using specific gene knockdown or overexpression approaches, we identify the critical role of BAF53b in the lateral amygdala neurons for memory consolidation during long-term memory formation.

  4. This study provided new insight into the role of dominant mutations in subunits of BAF complexes in human intellectual and cognitive disorders.

  5. BAF53b is combinatorially assembled into polymorphic complexes with ubiquitous subunits including the two ATPases BRG1 and BRM

Actin-Like 6B (ACTL6B) Protein Profile

Protein Summary

The protein encoded by this gene is a member of a family of actin-related proteins (ARPs) which share significant amino acid sequence identity to conventional actins. Both actins and ARPs have an actin fold, which is an ATP-binding cleft, as a common feature. The ARPs are involved in diverse cellular processes, including vesicular transport, spindle orientation, nuclear migration and chromatin remodeling. This gene encodes a subunit of the BAF (BRG1/brm-associated factor) complex in mammals, which is functionally related to SWI/SNF complex in S. cerevisiae and Drosophila\; the latter is thought to facilitate transcriptional activation of specific genes by antagonizing chromatin-mediated transcriptional repression. This subunit may be involved in the regulation of genes by structural modulation of their chromatin, specifically in the brain.

Gene names and symbols associated with Actin-Like 6B Proteins (ACTL6B)

  • actin-like 6B (actl6b)
  • actin like 6B (ACTL6B)
  • actin-like 6B (Actl6b)
  • Actl6 protein
  • ArpNa protein
  • Baf53b protein
  • MGC110167 protein
  • zgc:110167 protein

Protein level used designations for Actin-Like 6B Proteins (ACTL6B)

actin-like 6B , actin-like protein 6B-like , 53 kDa BRG1-associated factor B , BRG1-associated factor 53B , actin-like 6 , actin-like protein 6B , actin-related protein Baf53b , arpNalpha , hArpN alpha , arpN-alpha , BAF53B

GENE ID SPECIES
553775 Danio rerio
608417 Canis lupus familiaris
712643 Macaca mulatta
739528 Pan troglodytes
100357059 Oryctolagus cuniculus
100395638 Callithrix jacchus
100457823 Pongo abelii
100484805 Ailuropoda melanoleuca
100516853 Sus scrofa
100606190 Nomascus leucogenys
51412 Homo sapiens
83766 Mus musculus
288563 Rattus norvegicus
504476 Bos taurus
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