anti-Aminolevulinate Dehydratase (ALAD) Antibodies

The ALAD enzyme is composed of 8 identical subunits and catalyzes the condensation of 2 molecules of delta-aminolevulinate to form porphobilinogen (a precursor of heme, cytochromes and other hemoproteins). Additionally we are shipping Aminolevulinate Dehydratase Kits (41) and Aminolevulinate Dehydratase Proteins (11) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
ALAD 210 P13716
ALAD 25374 P06214
ALAD 17025 P10518
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Top anti-Aminolevulinate Dehydratase Antibodies at antibodies-online.com

Showing 10 out of 66 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Delivery Price Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-ALAD Antibody Titration:  0.2-1 ug/ml  Positive Control:  Jurkat cell lysate ALAD is supported by BioGPS gene expression data to be expressed in Jurkat WB Suggested Anti-ALAD  Antibody Titration: 0.2-1 µg/mL  Positive Control: Jurkat cell lysate  ALAD is supported by BioGPS gene expression data to be expressed in Jurkat 100 μL 2 to 3 Days
$289.00
Details
Cow Rabbit Un-conjugated IHC, WB WB Suggested Anti-ALAD Antibody Titration:  0.2-1 ug/ml  Positive Control:  Jurkat cell lysate ALAD is supported by BioGPS gene expression data to be expressed in Jurkat WB Suggested Anti-ALAD  Antibody Titration: 0.2-1 µg/mL  Positive Control: Jurkat cell lysate  ALAD is supported by BioGPS gene expression data to be expressed in Jurkat 100 μL 2 to 3 Days
$319.00
Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-ALAD Antibody Titration:  0.2-1 ug/ml  ELISA Titer:  1:312500  Positive Control:  Human heart Rabbit Anti-ALAD antibody  Formalin Fixed Paraffin Embedded Tissue: Human Adrenal Primary antibody Concentration: 1:100 Secondary Antibody: Donkey anti-Rabbit-Cy3 Secondary Antibody Concentration: 1:200 Magnification: 20x Exposure Time: 0.5-2.0sec 100 μL 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated WB WB Suggested Anti-ALAD Antibody Titration:  0.2-1 ug/ml  ELISA Titer:  1:312500  Positive Control:  Human Muscle 100 μL 2 to 3 Days
$289.00
Details
Cow Rabbit Un-conjugated WB Host: Rabbit Target Name: ALAD Sample Tissue: Mouse Thymus Antibody Dilution: 1ug/ml 100 μL 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated EIA, WB 0.4 mL 6 to 8 Days
$484.00
Details
Human Rabbit Un-conjugated WB 100 μL 11 to 14 Days
$581.17
Details
Bat Rabbit Un-conjugated WB 100 μL 11 to 14 Days
$551.83
Details
Human Rabbit Un-conjugated WB 100 μL 11 to 14 Days
$551.83
Details
Cow Rabbit Un-conjugated IHC, IHC (p), WB Human Adrenal: Formalin-Fixed, Paraffin-Embedded (FFPE). This image was taken for the unconjugated form of this product. Other forms have not been tested. 100 μL 11 to 14 Days
$727.83
Details

Top referenced anti-Aminolevulinate Dehydratase Antibodies

  1. Human Polyclonal ALAD Primary Antibody for WB - ABIN513229 : Anand, Wilson, Hasan, Maytin: Vitamin D3 enhances the apoptotic response of epithelial tumors to aminolevulinate-based photodynamic therapy. in Cancer research 2011 (PubMed)

  2. Cow (Bovine) Polyclonal ALAD Primary Antibody for WB - ABIN2776921 : Tang, Breinig, Stith, Mischel, Tannir, Kokona, Fairman, Jaffe: Single amino acid mutations alter the distribution of human porphobilinogen synthase quaternary structure isoforms (morpheeins). in The Journal of biological chemistry 2006 (PubMed)

  3. Human Polyclonal ALAD Primary Antibody for IHC, IHC (p) - ABIN4279102 : Moreno-Navarrete, Rodríguez, Ortega, Becerril, Girones, Sabater-Masdeu, Latorre, Ricart, Frühbeck, Fernández-Real: Heme Biosynthetic Pathway is Functionally Linked to Adipogenesis via Mitochondrial Respiratory Activity. in Obesity (Silver Spring, Md.) 2018 (PubMed)

More Antibodies against Aminolevulinate Dehydratase Interaction Partners

Human Aminolevulinate Dehydratase (ALAD) interaction partners

  1. Automobile paints workers with ALAD 1-2 genotype showed the positive association of blood lead levels with diastolic blood pressure whereas, a genotypic combination of ALAD 1-2/VDR BB showed the negative association of serum uric acid with BLL.

  2. ALAD genetic polymorphisms contribute to high blood lead levels in occupational exposed workers and may predict risk of lead poisoning.

  3. The delta-aminolevulinate dehydratase activity was significantly lower in pregnant women with gestational diabetes mellitus.

  4. The ALAD gene influences bone density among lead workers.

  5. The frequencies of genotype and allelic variants of ALAD rs1800435 did not differ significantly between patients with essential tremor (ET) and controls, and were not influenced by gender. Subjects carrying the ALAD rs1800435CC genotype (wild-type) and the HMOX2 rs1051308GG genotype or the HMOX2 rs1051308G allele had significantly decreased risk for ET.

  6. ALAD SNP rs818708 is significantly associated with risk of lead poisoning.

  7. Overexpression of delta-aminolevulinate dehydratase (ALAD)suppresses breast cancer cell proliferation and invasion and inhibits the epithelial-mesenchymal transition phenotype.

  8. Delta-aminolevulinate dehydratase activity and oxidative stress markers were significantly lowered in preeclampsia.

  9. Results show statistically significant association between the maternal ALAD G177C polymorphism and placental lead levels.

  10. Maternal ALAD gene polymorphism can affect early neonatal neurobehavioral development by influencing the blood lead level.

  11. Genetic variation of ALAD is associated with blood lead level.

  12. This study investigated the delta-aminolevulinate dehydratase (delta-ALA-D) activity in whole blood as well as the parameters of oxidative stress, in lung cancer.

  13. Blood lead level affected ALAD but not GPx activities, and these were not modulated by polymorphisms in ALAD and GPx genes.

  14. Study reveals relationship between ALAD genetic polymorphisms and basic lead toxicological parameters in occupationally exposed workers.

  15. This study showed that ALAD2 and hPEPT2*2 may be valuable markers of risk, and indicate novel mechanisms of lead-induced neurotoxicity

  16. The ff carriers in VDR FokI polymorphism were more susceptible to the effect of lead on the balance system, while other VDR or ALAD genotypes did not significantly modify the effect.

  17. The results indicate that the ALAD1-2/2-2 genotype may have a protective effect in terms of urinary aminolevulinic acid for environmentally lead exposed boys.

  18. Report the effect of ALAD polymorphism on hematopoietic, hepatic and renal toxicity from lead in occupational exposure workers.

  19. Genetic variation in ALAD may modify associations between Pb and prostate cancer

  20. The results lend support to the notion that ALAD polymorphism exerts no marked impact on lead body burden.

Mouse (Murine) Aminolevulinate Dehydratase (ALAD) interaction partners

  1. this study demonstrated for the first time the involvement of striatal delta-ALA-D activity in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine model and its correlation with the MPO activity.

  2. Similar to its role at the beta-globin promoter, KLF1 induces factor recruitment and chromatin changes at the Alad1b promoter in a temporally-specific manner

  3. The data supports the hypothesis that ALAD, an important enzyme for heme synthesis, is also important as a proteasome interacting protein.

  4. Delta-ALA-D from D. melanogaster and M.musculus has a different profile of optimum pH and different sensitivity for diphenyl diselenide and lead, two inhibitors.

Aminolevulinate Dehydratase (ALAD) Antigen Profile

Protein Summary

The ALAD enzyme is composed of 8 identical subunits and catalyzes the condensation of 2 molecules of delta-aminolevulinate to form porphobilinogen (a precursor of heme, cytochromes and other hemoproteins). ALAD catalyzes the second step in the porphyrin and heme biosynthetic pathway\; zinc is essential for enzymatic activity. ALAD enzymatic activity is inhibited by lead and a defect in the ALAD structural gene can cause increased sensitivity to lead poisoning and acute hepatic porphyria.

Gene names and symbols associated with ALAD

  • delta-aminolevulinate dehydratase (hemB) antibody
  • aminolevulinate dehydratase (ALAD) antibody
  • delta-aminolevulinic acid dehydratase (PBGS) antibody
  • delta-aminolevulinic acid dehydratase (STY0404) antibody
  • delta-aminolevulinic acid dehydratase (hemB) antibody
  • delta-aminolevulinic acid dehydratase (SAS1597) antibody
  • delta-aminolevulinic acid dehydratase (SACI_RS03725) antibody
  • delta-aminolevulinic acid dehydratase (ALAD) antibody
  • Delta-aminolevulinic acid dehydratase (hemB) antibody
  • delta-aminolevulinic acid dehydratase (PAAG_00299) antibody
  • delta-aminolevulinic acid dehydratase (VDBG_00315) antibody
  • delta-aminolevulinic acid dehydratase (HPPC_00830) antibody
  • delta-aminolevulinic acid dehydratase (MGYG_01952) antibody
  • Delta-aminolevulinic acid dehydratase (hem2) antibody
  • aminolevulinate dehydratase L homeolog (alad.L) antibody
  • aminolevulinate dehydratase (Alad) antibody
  • aminolevulinate dehydratase (alad) antibody
  • aminolevulinate, delta-, dehydratase (Alad) antibody
  • ALAD antibody
  • ALADH antibody
  • ALADR antibody
  • aminolevulinatedelta-dehydratase antibody
  • DDBDRAFT_0190269 antibody
  • DDBDRAFT_0231415 antibody
  • DDB_0190269 antibody
  • DDB_0231415 antibody
  • Lv antibody
  • ncf antibody
  • PBGS antibody
  • zgc:110219 antibody

Protein level used designations for ALAD

porphobilinogen synthase , aminolevulinate, delta-, dehydratase , delta-aminolevulinic acid dehydratase , Delta-aminolevulinic acid dehydratase , aminolevulinate dehydratase , delta-aminolevulinic acid dehydratase-like , ALADH , delta - aminolevulinic acid dehydratase

GENE ID SPECIES
8616919 Dictyostelium discoideum AX4
464675 Pan troglodytes
811963 Plasmodium falciparum 3D7
1246884 Salmonella enterica subsp. enterica serovar Typhi str. CT18
2662431 Bordetella bronchiseptica RB50
2860701 Staphylococcus aureus subsp. aureus MRSA252
2862870 Staphylococcus aureus subsp. aureus MSSA476
3092987 Burkholderia pseudomallei K96243
3233358 Ehrlichia ruminantium str. Welgevonden
3473841 Sulfolobus acidocaldarius DSM 639
4714527 Yersinia enterocolitica subsp. enterocolitica 8081
4913181 Clostridium difficile 630
5185178 Clostridium botulinum A str. ATCC 3502
5727479 Chlamydomonas reinhardtii
5858769 Chlamydia trachomatis 434/Bu
6933521 Burkholderia cenocepacia J2315
6988018 Aliivibrio salmonicida LFI1238
7758502 Laribacter hongkongensis HLHK9
8714875 Citrobacter rodentium ICC168
8865569 Helicobacter mustelae 12198
9100845 Paracoccidioides sp. 'lutzii' Pb01
9528824 Verticillium alfalfae VaMs.102
9747569 Halomonas elongata DSM 2581
9785237 Helicobacter pylori PeCan4
10033227 Arthroderma gypseum CBS 118893
10050382 Helicobacter felis ATCC 49179
100195823 Salmo salar
100393588 Callithrix jacchus
444422 Xenopus laevis
210 Homo sapiens
474808 Canis lupus familiaris
510679 Bos taurus
25374 Rattus norvegicus
550338 Danio rerio
417274 Gallus gallus
17025 Mus musculus
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