anti-Amyloid beta (Abeta) Antibodies

Abeta encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Additionally we are shipping beta Amyloid Kits (2) and and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
Abeta 351 P05067
Abeta 54226 P08592
Abeta 11820 P12023
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Top anti-beta Amyloid Antibodies at antibodies-online.com

Showing 10 out of 270 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Mouse Un-conjugated ELISA, ICC, IF, IHC, IHC (ff), IHC (p), IP, WB Immunocytochemistry/Immunofluorescence: beta Amyloid Antibody (MOAB-2) [NBP2-13075] - Immunofluorescent detection of beta Amyloid with MOAB-2 in the subiculim of 1-, 2- and 4- month old 5xFAD mice. Scale bar 20 um (from PMID: 22423893). Immunohistochemistry: beta Amyloid Antibody (MOAB-2) [NBP2-13075] - IHC analysis of beta Amyloid on normal mouse brain (left) and 5xFAD mouse brain (right) using DAB with hematoxylin counterstain. The MOAB-2 antibody was used at 1:20 on normal mouse brain and at 1:400 on 5xFAD mouse brain. 0.1 mL Log in to see 7 to 9 Days
$514.63
Details
Human Rabbit Un-conjugated IHC, ELISA, WB 100 μg Log in to see 1 to 2 Days
$389.00
Details
Cow Rabbit Un-conjugated WB Western blot analysis of Beta Amyloid expression in HEK293T (A), Hela (B) whole cell lysates. 200 μL Log in to see 13 to 14 Days
$487.50
Details
Chicken Rabbit Un-conjugated IHC, WB Immunohistochemical analysis of Beta Amyloid (pT743) staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. Western blot analysis of Beta Amyloid (pT743) expression in MCF7 colchicine-treated (A), mouse liver (B), PC12 (C) whole cell lysates. 200 μL Log in to see 13 to 14 Days
$575.00
Details
Mouse Goat Un-conjugated ELISA, WB Western Blot: beta Amyloid Antibody [NBP1-97755] - (0.03ug/ml) Analysis of Mouse Brain lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 0.1 mg Log in to see 7 to 9 Days
$485.88
Details
Human Rabbit Un-conjugated ELISA, IHC, IHC (p), WB Immunohistochemistry: beta Amyloid Antibody [NBP2-25093] - Analysis of APP in human brain tissue with APP antibody at 2.5 ug/ml. Immunohistochemistry-Paraffin: beta Amyloid Antibody [NBP2-25093] - Human brain (Alzheimer's disease) tissue with APP antibody at 10 ug/mL. 0.1 mg Log in to see 8 to 11 Days
$485.88
Details
Cow Rabbit Un-conjugated ELISA, ICC, IF, IHC, Act (ligand), WB Western Blot: beta Amyloid [Pyro Glu3] Antibody [NBP1-44048] - Lane 1-10: beta Amyloid pyro E3 peptide. Load: 1 ug per lane 1-2, 0.2 ug per lane 3-4, 0.05 ug per lane 5-6, 0.01 ug per lane 7-8, 0.005 ug per lane 9-10. Primary antibody: Beta Amyloid pyro E3 antibody at 0.5 ug/mL for overnight at 4C. Secondary antibody: IRDye800 rabbit secondary antibody at 1:10,000 for 45 min at RT. Block: 5% BLOTTO overnight at 4C. Predicted/Observed size: 86.9 kDa for beta Amyloid pyro E3 peptide. Cross reactivity with Beta Amyloid 3 peptide is >1000 fold below pyrE3 reactivity and contains no reactivity towards the Beta Amyloid 42 A beta peptide (data not shown). Immunocytochemistry/Immunofluorescence: beta Amyloid [Pyro Glu3] Antibody [NBP1-44048] - Laser scanning confocal microscopy was carried out using human tissue sections from frontal cortex. Figure A shows an example section that was immunostained for the presence of pyrE3Abeta (green). Figure B shows that the immunogen peptide completely blocked the NBP1-44048 antibody. 0.05 mg Log in to see 7 to 9 Days
$585.06
Details
Human Rabbit Un-conjugated WB Western blot analysis of Beta Amyloid expression in mouse kidney (A), mouse heart (B) whole cell lysates. 200 μL Log in to see 13 to 14 Days
$487.50
Details
Human Rabbit Un-conjugated EIA, IF, IHC (p), WB 0.1 mg Log in to see 6 to 8 Days
$533.50
Details
Fruit Fly Rabbit Un-conjugated ELISA, ICC, IF, IHC, Act (ligand), WB Immunocytochemistry/Immunofluorescence: beta Amyloid [Pyro Glu11] Antibody [NBP1-44070] - beta-amyloid (pyroglu11) NBP1-44070 in red (left) co-labeled with 6E10 in green (middle) and merge (right). Image from verified customer review. Immunocytochemistry/Immunofluorescence: beta Amyloid [Pyro Glu11] Antibody [NBP1-44070] - Laser scanning confocal microscopy was carried out using human tissue sections from frontal cortex. Figure A shows an example section that was immunostained for the presence of pyrE11Abeta (green). Figure B shows that the immunogen peptide completely blocked the NBP1-44070 antibody. 0.05 mg Log in to see 7 to 9 Days
$585.06
Details

Abeta Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-beta Amyloid Antibodies

  1. Human Monoclonal beta Amyloid Primary Antibody for ELISA, ICC - ABIN4284085 : Youmans, Tai, Kanekiyo, Stine, Michon, Nwabuisi-Heath, Manelli, Fu, Riordan, Eimer, Binder, Bu, Yu, Hartley, LaDu: Intraneuronal Aβ detection in 5xFAD mice by a new Aβ-specific antibody. in Molecular neurodegeneration 2012 (PubMed)
    Show all 10 Pubmed References

  2. Cow (Bovine) Polyclonal beta Amyloid Primary Antibody for ELISA, ICC - ABIN4284076 : He, Barrow: The A beta 3-pyroglutamyl and 11-pyroglutamyl peptides found in senile plaque have greater beta-sheet forming and aggregation propensities in vitro than full-length A beta. in Biochemistry 1999 (PubMed)
    Show all 4 Pubmed References

  3. Human Monoclonal beta Amyloid Primary Antibody for ELISA, IF - ABIN5508784 : Markoutsa, Papadia, Clemente, Flores, Antimisiaris: Anti-Aβ-MAb and dually decorated nanoliposomes: effect of Aβ1-42 peptides on interaction with hCMEC/D3 cells. in European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft für Pharmazeutische Verfahrenstechnik e.V 2012 (PubMed)
    Show all 4 Pubmed References

  4. Human beta Amyloid Primary Antibody for ELISA (Capture), IF - ABIN1110165 : Levites, Jansen, Smithson, Dakin, Holloway, Das, Golde et al.: Intracranial adeno-associated virus-mediated delivery of anti-pan amyloid beta, amyloid beta40, and amyloid beta42 single-chain variable fragments attenuates plaque pathology in amyloid precursor ... in The Journal of neuroscience : the official journal of the Society for Neuroscience 2006 (PubMed)
    Show all 3 Pubmed References

  5. Fruit Fly (Drosophila melanogaster) Polyclonal beta Amyloid Primary Antibody for ELISA, ICC - ABIN4284077 : Youssef, Florent-Béchard, Malaplate-Armand, Koziel, Bihain, Olivier, Leininger-Muller, Kriem, Oster, Pillot: N-truncated amyloid-beta oligomers induce learning impairment and neuronal apoptosis. in Neurobiology of aging 2008 (PubMed)
    Show all 3 Pubmed References

  6. Human beta Amyloid Primary Antibody for IF, IP - ABIN1110164 : Levites, Smithson, Price, Dakin, Yuan, Sierks, Kim, McGowan, Reed, Rosenberry, Das, Golde: Insights into the mechanisms of action of anti-Abeta antibodies in Alzheimer's disease mouse models. in FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2006 (PubMed)
    Show all 2 Pubmed References

  7. Human beta Amyloid Primary Antibody for ELISA (Capture), ELISA (Detection) - ABIN1110166 : Levites, Das, Price, Rochette, Kostura, McGowan, Murphy, Golde: Anti-Abeta42- and anti-Abeta40-specific mAbs attenuate amyloid deposition in an Alzheimer disease mouse model. in The Journal of clinical investigation 2006 (PubMed)
    Show all 2 Pubmed References

  8. Human Polyclonal beta Amyloid Primary Antibody for IHC (fro), IHC (p) - ABIN2477631 : Romaguera, Grimalt, Vilaplana: Eczematous and purpuric allergic contact dermatitis from boots. in Contact dermatitis 1990 (PubMed)
    Show all 3 Pubmed References

  9. Human Polyclonal beta Amyloid Primary Antibody for ELISA, WB - ABIN1573928 : Jia, Liu, Song, Pan, Chen, Cui, Wang: Berberine suppresses amyloid-beta-induced inflammatory response in microglia by inhibiting nuclear factor-kappaB and mitogen-activated protein kinase signalling pathways. in The Journal of pharmacy and pharmacology 2012 (PubMed)

More Antibodies against beta Amyloid Interaction Partners

Human Amyloid beta (Abeta) interaction partners

  1. These results confirm the involvement of amyloid precursor protein (APP (show APP Antibodies)) in synaptogenesis and provide evidence to suggest that human APP (show APP Antibodies) overexpression specifically disturbs the structural and functional organization of active zone and results in altered Bruchpilot distribution and lowered probability of spontaneous neurotransmitter release.

  2. Study showed that the APP (show APP Antibodies) Osaka mutation has dual effects: it causes a loss-of-function of APP (show APP Antibodies) and gain-of-toxic-function of Abeta (show APP Antibodies), though the latter seems to come out only after the former causes GABAergic depletion. Also present OSK-KI mice as a mouse model to replicate the hereditary form of recessive familial Alzheimer's disease.

  3. results suggest that co-oligomers are a common form of aggregate when Abeta (show APP Antibodies) isoforms are present in solution and may potentially play a significant role in Alzheimer's disease.

  4. This study reports the transition dipole strengths and frequencies of the amyloid beta-sheet amide I mode for the aggregated proteins amyloid-beta1-40, calcitonin (show CALCA Antibodies), alpha-synuclein, and glucagon (show GCG Antibodies).

  5. Overall, these findings suggest that the ability of apoE (show APOE Antibodies) fragments to promote Abeta42 intraneuronal accumulation is specific for both the apoE4 isoform and the particular structural and thermodynamic properties of the fragment.

  6. This study structurally characterized ABETA (show APP Antibodies) 40 and ABETA (show APP Antibodies) 42 monomers through pentamers which were converted from previously derived coarse-grained (DMD4B-HYDRA) simulations into all-atom conformations and subjected to explicit-solvent Molecular Dynamics.

  7. Shape complementarity between close-packed residues plays a critical role in the amyloid aggregation process. This study probes such "steric zipper" interactions in amyloid-beta (ABETA (show APP Antibodies) 40), whose aggregation is linked to Alzheimer's disease, by replacing natural residues by their stereoisomers. Stereoisomers can cause complex site dependent changes in amyloid properties.

  8. Besides, the promoting effect of Zn2+ on ABETA42 fast aggregation peaked at pH 6.8-7.8, which includes the pH values of the cerebrospinal fluid (pH 7.3) and hippocampus (pH 7.15-7.35). The findings demonstrate the significant effect of Zn2+ on ABETA (show APP Antibodies) aggregation and provide new insight into its mechanisms.

  9. Taken together, these results suggest that ApoE4 enhances Abeta (show APP Antibodies) inhibition of insulin (show INS Antibodies)-stimulated AMPA (show GRIA3 Antibodies) receptor function, which accelerates memory impairment in ApoE4xAPP mice.

  10. The authors found that as already shown for oligomeric Abeta (show APP Antibodies), also oligomeric Tau can bind to amyloid precursor protein (APP (show APP Antibodies)). Moreover, efficient intra-neuronal uptake of oligomeric Abeta (show APP Antibodies) and oligomeric Tau requires expression of APP (show APP Antibodies).

Mouse (Murine) Amyloid beta (Abeta) interaction partners

  1. Study showed that the APP (show APP Antibodies) Osaka mutation has dual effects: it causes a loss-of-function of APP (show APP Antibodies) and gain-of-toxic-function of Abeta (show APP Antibodies), though the latter seems to come out only after the former causes GABAergic depletion. Also present OSK-KI mice as a mouse model to replicate the hereditary form of recessive familial Alzheimer's disease.

  2. Results show that the duration of UP state, which is a key feature of cortical synaptic integration occurring predominantly during slow-wave sleep, is significantly increased in the prefrontal cortex in the absence of APP (show APP Antibodies). This was accompanied by a specific reduction in the glutamine synthetase (show GLUL Antibodies) and tissue GABA content and sequential upregulation in the levels of GABA-B receptor expression.

  3. results support the hypothesis that the miR (show MLXIP Antibodies)-132/212 network, including Sirt1 (show SIRT1 Antibodies) and likely other target genes, contributes to abnormal Abeta (show APP Antibodies) metabolism and senile plaque deposition in AD.

  4. Activation of CaMKIV (show CAMK4 Antibodies) by soluble amyloid-beta1-42 impedes trafficking of axonal vesicles and impairs activity-dependent synaptogenesis

  5. Abpp (show APP Antibodies) /KPI(R13I) mutant mice were similarly deficient as Abpp (show APP Antibodies) knock out mice in regulating cerebral thrombosis in experimental models of carotid artery thrombosis and intracerebral hemorrhage.

  6. The cognitive function of APP (show APP Antibodies)/PS1 (show PSEN1 Antibodies) mice was impaired at 10months of age; moreover, the hypermetabolic state identified in various brain regions at 5months of age was also significantly decreased.

  7. APP (show APP Antibodies) heterozygosity results in greater decreases of cortical APP (show APP Antibodies) in Transgenic (Tg) versus non-Tg mice. Mutant huntingtin (show HTT Antibodies) transgenic mice develop brain iron accumulation as a result of greater suppression of APP (show APP Antibodies) levels. Elevated brain iron in Tg mice was associated with a decline in motor endurance consistent with a disease promoting effect of iron in the YAC128 model of human Huntington's Disease.

  8. Mass spectrometry analysis of APP (show APP Antibodies) intracellular domains revealed differential processing of APP (show APP Antibodies)-C83, APP (show APP Antibodies)-C89, and APP (show APP Antibodies)-C99 by gamma-secretase already at the epsilon-cleavage stage. This mechanistic insight could aid in developing substrate-targeted modulators of APP (show APP Antibodies)-C99 processing to specifically lower the Abeta42:Abeta40 ratio without compromising gamma-secretase function.

  9. Data show that exosomal amyloid precursor protein C-terminal fragments (APP-CTFs) and bis(monoacylglycero)phosphate (BMP) as candidate biomarkers diagnostic of endolysosomal dysfunction associated with neurodegenerative disorders.

  10. study provides molecular insights into the design of amyloidogenic inhibitors to cure various neurodegenerative and amyloid-associated diseases, as NABi would regulate aggregation of other toxic beta-sheet proteins other than Abeta (show APP Antibodies).

beta Amyloid (Abeta) Antigen Profile

Protein Summary

This gene encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease. Mutations in this gene have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy). Multiple transcript variants encoding several different isoforms have been found for this gene.

Gene names and symbols associated with anti-Amyloid beta (Abeta) Antibodies

  • amyloid beta precursor protein (APP) antibody
  • amyloid beta precursor protein (app) antibody
  • amyloid beta precursor protein (App) antibody
  • amyloid beta (A4) precursor protein (App) antibody
  • aaa antibody
  • Abeta antibody
  • Abpp antibody
  • ad1 antibody
  • Adap antibody
  • Ag antibody
  • appi antibody
  • betaApp antibody
  • ctfgamma antibody
  • Cvap antibody
  • E030013M08Rik antibody
  • PN-II antibody
  • pn2 antibody

Protein level used designations for anti-Amyloid beta (Abeta) Antibodies

alzheimer disease amyloid protein , amyloid beta A4 protein , beta-amyloid peptide , cerebral vascular amyloid peptide , peptidase nexin-II , preA4 , protease nexin-II , amyloid beta (A4) precursor protein (peptidase nexin-2, Alzheimer disease) , amyloid beta (A4) precursor protein (protease nexin-II, Alzheimer disease) , beta-amyloid precursor protein , alzheimer disease amyloid A4 protein homolog , amyloid beta (A4) precursor protein (peptidase nexin-II, Alzheimer disease) , ABPP , AG , amyloid A4 , amyloidogenic glycoprotein , appican , protease nexin II

GENE ID SPECIES
351 Homo sapiens
448208 Xenopus (Silurana) tropicalis
100427716 Macaca mulatta
54226 Rattus norvegicus
11820 Mus musculus
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