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beta Amyloid Products

(Amyloid beta (Abeta))
This gene encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease. Mutations in this gene have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy). Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].

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Featured beta Amyloid Categories

beta Amyloid Antibodies

High quality antibodies with extensive validation data.

beta Amyloid ELISA Kits

Reliable ELISA kits for a wide range of species.

beta Amyloid Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended beta Amyloid Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse
Application IHC, ELISA, WB
Validations
  • (1)
  • (7)
  • (2)
Cat. No. ABIN95037
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application ELISA, IF, IHC, IHC (p), WB
Validations
  • (3)
Cat. No. ABIN2888562
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application IF, ELISA, WB
Validations
  • (2)
Cat. No. ABIN1573929
Quantity 40 μg
Datasheet Datasheet

Recommended beta Amyloid ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN2708079
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative
Validations
  • (1)
Cat. No. ABIN1882410
Quantity 1 kit
Datasheet Datasheet
Reactivity Mouse, Rat
Analytical Method Quantitative
Validations
  • (1)
Cat. No. ABIN1882413
Quantity 1 kit
Datasheet Datasheet

Recommended beta Amyloid Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Synthetic
Validations
Cat. No. ABIN7272125
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN5849635
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our beta Amyloid products

He, Ruganzu, Lin, Ding, Zheng, Wu, Ma, Liu, Wang, Jin, Qian, Peng, Ji, Zhang, Yang, Lei: "Tanshinone IIA ameliorates cognitive deficits by inhibiting endoplasmic reticulum stress-induced apoptosis in APP/PS1 transgenic mice." in: Neurochemistry international, Vol. 133, pp. 104610, (2020) (PubMed).

Jendresen, Digre, Cui, Zhang, Vlodavsky, Li, Nilsson: "Systemic LPS-induced Aβ-solubilization and clearance in AβPP-transgenic mice is diminished by heparanase overexpression." in: Scientific reports, Vol. 9, Issue 1, pp. 4600, (2020) (PubMed).

El Hajjar, Chatoo, Hanna, Nkanza, Tétreault, Tse, Wong, Abdouh, Bernier: "Heterochromatic genome instability and neurodegeneration sharing similarities with Alzheimer's disease in old Bmi1+/- mice." in: Scientific reports, Vol. 9, Issue 1, pp. 594, (2019) (PubMed).

Woodhouse, Fernandez-Martos, Atkinson, Hanson, Collins, OMara, Terblanche, Skinner, Vickers, King: "Repeat propofol anesthesia does not exacerbate plaque deposition or synapse loss in APP/PS1 Alzheimer's disease mice." in: BMC anesthesiology, Vol. 18, Issue 1, pp. 47, (2019) (PubMed).

Cristiano, Volpicelli, Lippiello, Buono, Raucci, Piccolo, Iqbal, Irace, Miniaci, Perrone Capano, Calignano, Mascolo, Maione: "Neutralization of IL-17 rescues amyloid-β-induced neuroinflammation and memory impairment." in: British journal of pharmacology, (2019) (PubMed).

Collins, King, Woodhouse, Kirkcaldie, Vickers: "Age moderates the effects of traumatic brain injury on beta-amyloid plaque load in APP/PS1 mice." in: Journal of neurotrauma, (2019) (PubMed).

Kim, Lee, Lim, Choi, Oh, Yang, Chang, Jeon: "Effect of growth differentiation factor-15 secreted by human umbilical cord blood-derived mesenchymal stem cells on amyloid beta levels in in vitro and in vivo models of Alzheimer's disease." in: Biochemical and biophysical research communications, Vol. 504, Issue 4, pp. 933-940, (2019) (PubMed).

Choi, Yeo, Kim, Choi, Jung, Han, Hong: "K284-6111 prevents the amyloid beta-induced neuroinflammation and impairment of recognition memory through inhibition of NF-κB-mediated CHI3L1 expression." in: Journal of neuroinflammation, Vol. 15, Issue 1, pp. 224, (2019) (PubMed).

Tian, Liu, Gao, Soltys, Pan, Stewart, Shi, Xie, Liu, Feng, Zhang: "Erythrocytic α-Synuclein as a potential biomarker for Parkinson's disease." in: Translational neurodegeneration, Vol. 8, pp. 15, (2019) (PubMed).

Prokop, Miller, Labra, Pitkin, Hoxha, Narasimhan, Changolkar, Rosenbloom, Lee, Trojanowski: "Impact of TREM2 risk variants on brain region-specific immune activation and plaque microenvironment in Alzheimer's disease patient brain samples." in: Acta neuropathologica, (2019) (PubMed).

Synonyms and alternative names related to beta Amyloid

amyloid beta precursor protein (APP), amyloid beta precursor protein (app), amyloid beta precursor protein (App), amyloid beta (A4) precursor protein (App), AAA, aaa, ABETA, abeta, Abeta, ABPP, abpp, Abpp, AD1, ad1, Adap, Ag, APPI, appi, betaApp, CTFgamma, ctfgamma, CVAP, cvap, Cvap, E030013M08Rik, PN-II, PN2, pn2

Protein level used designations for beta Amyloid

  • alzheimer disease amyloid protein
  • amyloid beta A4 protein
  • beta-amyloid peptide
  • cerebral vascular amyloid peptide
  • peptidase nexin-II
  • preA4
  • protease nexin-II
  • amyloid beta (A4) precursor protein (peptidase nexin-2, Alzheimer disease)
  • amyloid beta (A4) precursor protein (protease nexin-II, Alzheimer disease)
  • beta-amyloid precursor protein
  • alzheimer disease amyloid A4 protein homolog
  • amyloid beta (A4) precursor protein (peptidase nexin-II, Alzheimer disease)
  • ABPP
  • AG
  • amyloid A4
  • amyloidogenic glycoprotein
  • appican
  • protease nexin II
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