anti-Angiogenic Factor with G Patch and FHA Domains 1 (AGGF1) Antibodies

AGGF1 encodes an angiogenic factor that promotes proliferation of endothelial cells. Additionally we are shipping AGGF1 Kits (37) and AGGF1 Proteins (10) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
AGGF1 310005  
AGGF1 55109 Q8N302
AGGF1 66549 Q7TN31
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Top anti-AGGF1 Antibodies at antibodies-online.com

Showing 10 out of 97 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-AGGF1 Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:1562500 Positive Control: 293T cell lysate AGGF1 is strongly supported by BioGPS gene expression data to be expressed in Human HEK293T cells 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated WB AGGF1 Antibody (N-term) (ABIN658163) western blot analysis in ZR-75-1 cell line lysates (35 µg/lane). This demonstrates the AGGF1 antibody detected the AGGF1 protein (arrow). 400 μL Log in to see 10 to 11 Days
$385.00
Details
Human Rabbit Un-conjugated ICC, IF, IP, IHC, ELISA, WB Human VG5Q detected in HT1080 non-transfected cell lysate (NTC) and HT1080 transfected cell lysate (TC) using ABIN151902. Immunohistochemistry-Paraffin: VG5Q Antibody  - VG5Q was detected in immersion fixed paraffin-embedded sections of human liver using Rabbit Anti-Human VG5Q polyclonal Antibody . Specific staining was localized to the cytoplasm in hepatocytes. 0.1 mL Log in to see 7 to 9 Days
$418.10
Details
Guinea Pig Rabbit Un-conjugated WB 50 μg Log in to see 11 to 14 Days
$551.83
Details
Human Rabbit Un-conjugated IHC, WB ABIN6272953 at 1/100 staining Human Melanoma tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary. Western blot analysis of extracts of mouse liver tissue, using AGGF1 antibody. 100 μL Log in to see 11 to 12 Days
$390.77
Details
Human Rabbit Un-conjugated IF, IP, WB Immunoprecipitation of AGGF1 transfected lysate using anti-AGGF1 MaxPab rabbit polyclonal antibody and Protein A Magnetic Bead , and immunoblotted with AGGF1 purified MaxPab mouse polyclonal antibody (B02P) . Western Blot analysis of AGGF1 expression in transfected 293T cell line by AGGF1 MaxPab polyclonal antibody.Lane 1: AGGF1 transfected lysate(80.9 KDa).Lane 2: Non-transfected lysate. 100 μL Log in to see 11 to 12 Days
$425.71
Details
Mouse Rabbit Un-conjugated ICC, IF, IP, IHC, ELISA, WB Murine VG5Q detected in mouse skin protein extracts using ABIN151903. 0.1 mL Log in to see 7 to 9 Days
$418.10
Details
Human Rabbit Un-conjugated IF (p), IHC (p), WB Antigen: 0.2 µg/100 µL  Primary: Antiserum, 1:500, 1:1000, 1:2000, 1:4000, 1:8000, 1:16000, 1:32000;  Secondary: HRP conjugated Goat Anti-Rabbit IgG at 1: 5000;  TMB staining; Read the data in Microplate Reader by 450nm Lane 1: mouse lung lysates Lane 2: mouse intestine lysates probed with Anti VG5Q/AGGF1 Polyclonal Antibody, Unconjugated (ABIN722380) at 1:200 in 4 °C. Followed by conjugation to secondary antibody at 1:3000 90min in 37 °C. Predicted band 79kD. Observed band size: 79kD. 100 μL Log in to see 3 to 7 Days
$317.90
Details
Human Rabbit Un-conjugated ICC, IHC, WB Used in DAB staining on fromalin fixed paraffin-embedded Intestine tissue 100 μg Log in to see 13 to 16 Days
$384.00
Details
Human Rabbit Un-conjugated ICC, IHC, WB Used in DAB staining on fromalin fixed paraffin-embedded Intestine tissue 100 μg Log in to see 15 to 18 Days
$386.00
Details

Top referenced anti-AGGF1 Antibodies

  1. Polyclonal AGGF1 Primary Antibody for IHC (fro), WB - ABIN540425 : Tian, Kadaba, You, Liu, Timur, Yang, Chen, Szafranski, Rao, Wu, Housman, DiCorleto, Driscoll, Borrow, Wang: Identification of an angiogenic factor that when mutated causes susceptibility to Klippel-Trenaunay syndrome. in Nature 2004 (PubMed)

More Antibodies against AGGF1 Interaction Partners

Zebrafish Angiogenic Factor with G Patch and FHA Domains 1 (AGGF1) interaction partners

  1. Bmp-induced activation of beta-catenin through Aggf1 regulates caudal vein development by promoting the Nr2f2-dependent differentiation of venous endothelial cells and their survival.

  2. aggf1 is involved in differentiation of both hematopoietic and endothelial lineages and acts upstream of scl, fli1, and etsrp in specification of hemangioblasts

  3. Our study establishes AGGF1 as an angiogenic factor with an important role in the specification of vein identity and suggests that AGGF1-mediated AKT signaling is responsible for establishing venous cell fate

Human Angiogenic Factor with G Patch and FHA Domains 1 (AGGF1) interaction partners

  1. Aggf1 has a role in regulating vascular injury.

  2. High expression of AGGF1 predicts poor prognosis in gastric cancer patients.

  3. AGGF1 gene polymorphism does not affect the risk of varicose veins of the legs in ethnic Russians.

  4. Overexpression of AGGF1 is correlated with angiogenesis in hepatocellular carcinoma.

  5. AGGF1 reduces myocardial apoptosis and inflammation and enhances angiogenesis, leading to decreased infarct size after I/R injury.

  6. results of this study indicate that hypoxia down-regulates expression of the AGGF1 protein, but not AGGF1 mRNA, by inducing expression of miR-27a

  7. AGGF1 potently attenuated TNF-alpha triggered NF-kappaB pathway, as indicated by the decreased promoter activity, nuclear distribution and phosphorylation of NF-kappaB p65 subunit as well as the increased protein level of IkappaBalpha.

  8. analysis of sphingolipid modulation of angiogenic factor expression in neuroblastoma

  9. results define VG5Q as an angiogenic factor, establish VG5Q as a susceptibility gene for Klippel-Trenaunay syndrome, and show that increased angiogenesis is a molecular pathogenic mechanism of KTS

  10. VG5Q, E133K is a mutation that causes Klippel-Trenaunay and other overgrowth syndromes.

  11. This review describes the somatic mutation for angiogenic factor VG5Q, which may be the cause of the multisystem disorder Klippel-Trenaunay syndrome.

  12. identified two tagSNPs, rs13155212 and rs7704267 that capture information for all common variants in AGGF1 as a candidate susceptibility gene for Klippel-Trenaunay syndrome

  13. Knockdown of GATA1 expression by siRNA reduced expression of AGGF1, and resulted in endothelial cell apoptosis and inhibition of vessel formation.

Mouse (Murine) Angiogenic Factor with G Patch and FHA Domains 1 (AGGF1) interaction partners

  1. AGGF1 protein therapy is effective in blocking neointimal formation after vascular injury by regulating a novel AGGF1-MEK1/2-ERK1/2-Elk-myocardin-SRF/p27 signaling pathway.

  2. Together with recent identification of somatic mutations in p110a (encoded by PIK3CA), our data establish a potential mechanistic link between AGGF1 and PIK3CA, the two genes identified for Klippel-Trenaunay syndrome (KTS)

  3. Data indicate that angiogenic factor Aggf1+/- knockout (KO) mice show reduced autophagy, which was associated with inhibition of angiogenesis and larger infarct areas.

  4. Mechanistically, Aggf1 activated the expression of gluconeogenesis gene and skewed the insulin signaling pathway to induce insulin resistance. Taken together, our data suggest that Aggf1 plays a role in steatosis in vivo and as such may be a new target in the development of therapeutics solutions against steatosis.

  5. Sphingolipid modulation of angiogenic factor expression in neuroblastoma

AGGF1 Antigen Profile

Protein Summary

This gene encodes an angiogenic factor that promotes proliferation of endothelial cells. Mutations in this gene are associated with a susceptibility to Klippel-Trenaunay syndrome. Pseudogenes of this gene are found on chromosomes 3, 4, 10 and 16.

Gene names and symbols associated with AGGF1

  • angiogenic factor with G patch and FHA domains 1 (Aggf1) antibody
  • angiogenic factor with G-patch and FHA domains 1 (AGGF1) antibody
  • angiogenic factor with G patch and FHA domains 1 (aggf1) antibody
  • angiogenic factor with G patch and FHA domains 1 (CC1G_06398) antibody
  • angiogenic factor with G-patch and FHA domains 1 (aggf1) antibody
  • angiogenic factor with G-patch and FHA domains 1 (Aggf1) antibody
  • 2010009L17Rik antibody
  • 2310029P06Rik antibody
  • AGGF1 antibody
  • AW112072 antibody
  • DKFZp459G1317 antibody
  • GPATC7 antibody
  • GPATCH7 antibody
  • HSU84971 antibody
  • HUS84971 antibody
  • im:7146636 antibody
  • LOC100037685 antibody
  • Peg3 antibody
  • RGD1310888 antibody
  • VG5Q antibody
  • zgc:152959 antibody

Protein level used designations for AGGF1

angiogenic factor with G patch and FHA domains 1 , angiogenic factor VG5Q , G patch domain-containing protein 7 , vasculogenesis gene on 5q protein

GENE ID SPECIES
310005 Rattus norvegicus
471508 Pan troglodytes
100037685 Ovis aries
479176 Canis lupus familiaris
559905 Danio rerio
707686 Macaca mulatta
6012856 Coprinopsis cinerea okayama7130
100073274 Equus caballus
100145680 Xenopus (Silurana) tropicalis
100172934 Pongo abelii
100483706 Ailuropoda melanoleuca
100565487 Anolis carolinensis
100585011 Nomascus leucogenys
55109 Homo sapiens
66549 Mus musculus
511650 Bos taurus
100520064 Sus scrofa
416364 Gallus gallus
100722136 Cavia porcellus
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