anti-Apelin Receptor (APLNR) Antibodies

APLNR encodes a member of the G protein-coupled receptor gene family. Additionally we are shipping Apelin Receptor Kits (21) and Apelin Receptor Proteins (6) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
APLNR 23796 Q9WV08
APLNR 83518 Q9JHG3
APLNR 187 P35414
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Top anti-Apelin Receptor Antibodies at antibodies-online.com

Showing 10 out of 185 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Dog Rabbit Un-conjugated WB WB Suggested Anti-APLNR Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:62500 Positive Control: MCF7 cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Dog Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Mouse Un-conjugated CyTOF, FACS, IHC APJ in Human Brain. APJ was detected in immersion fixed paraffin-embedded sections of human brain (basal ganglia) using 8 ug/mL Human APJ Monoclonal Antibody. APJ in Human Kidney. APJ was detected in immersion fixed paraffin-embedded sections of human kidney using Human APJ Monoclonal Antibody  at 25 ug/mL overnight at 4 ᄚC. Tissue was stained using the Anti-Mouse HRP-DAB Cell & 500 μg Log in to see 8 to 9 Days
$799.25
Details
Human Rabbit Un-conjugated FACS, IF (p), IHC (p), WB Formalin-fixed and paraffin-embedded : rat ovary tissue labeled with Rabbit Anti-APELIN RECEPTOR Polyclonal Antibody, Unconjugated (ABIN740160) 1:200 followed by conjugation to the secondary antibody and DAB staining Mouse splenocytes probed with Rabbit Anti-APJ Receptor Polyclonal Antibody, Unconjugated . 100 μL Log in to see 3 to 7 Days
$318.45
Details
Chicken Rabbit Un-conjugated WB Western blot analysis of APJ expression in HeLa (A), mouse lung (B), rat liver (C) whole cell lysates. 200 μL Log in to see 13 to 14 Days
$487.50
Details
Human Mouse APC FACS Detection of APJ in A172 Human Glioblastoma Cell Line by Flow Cytometry. A172 human glioblastoma cell line was stained with Mouse Anti-Human APJ APC-conjugated Monoclonal Antibody. 100 Tests Log in to see 8 to 9 Days
$385.25
Details
Human Rabbit Un-conjugated ICC, IF, IHC (p), IHC, WB Western Blot: APJ/Apelin receptor Antibody [NBP1-30869] - Sample (30 ug of whole cell lysate) A: U87-MG 10% SDS PAGE; antibody diluted at 1:1000. Immunohistochemistry-Paraffin: APJ/Apelin receptor Antibody [NBP1-30869] - Paraffin-embedded OVCA xenograft, using antibody at 1:100 dilution. 100 μL Log in to see 8 to 11 Days
$556.31
Details
Human Rabbit Un-conjugated IF, ELISA, WB Western blot analysis of extracts from HT-29 cells, using AGTRL1 Antibody. The lane on the right is treated with the synthesized peptide. Immunofluorescence analysis of MCF7 cells, using AGTRL1 Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Rabbit Un-conjugated WB APLNR Antibody (Center) (ABIN658044) western blot analysis in HL-60 cell line lysates (35 µg/lane). This demonstrates the APLNR antibody detected the APLNR protein (arrow). 400 μL Log in to see 10 to 11 Days
$335.50
Details
Human Rabbit Un-conjugated ICC, IF, IHC (p), WB WB Image Sample (30 ug of whole cell lysate) A: U87-MG 10% SDS PAGE antibody diluted at 1:1000 ICC/IF Image Immunofluorescence analysis of methanol-fixed A431, using Apelin Receptor, antibody at 1:500 dilution. 100 μL Log in to see 1 to 2 Days
$358.60
Details

APLNR Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-Apelin Receptor Antibodies

  1. Human Polyclonal Apelin Receptor Primary Antibody for FACS, IF (p) - ABIN740160 : Ustunel, Acar, Gemici, Ozbey, Edizer, Soylu, Tepekoy, Izgut-Uysal: The effects of water immersion and restraint stress on the expressions of apelin, apelin receptor (APJR) and apoptosis rate in the rat heart. in Acta histochemica 2014 (PubMed)
    Show all 2 Pubmed References

  2. Human Monoclonal Apelin Receptor Primary Antibody for CyTOF, FACS - ABIN4899111 : Bahrami, Pagh, Ejegod, Duch, Tolstrup, Pedersen: Construction of a gammaretrovirus with a novel tropism and wild-type replication kinetics capable of using human APJ as entry receptor. in Journal of virology 2012 (PubMed)
    Show all 2 Pubmed References

  3. Human Monoclonal Apelin Receptor Primary Antibody for FACS - ABIN4895622 : Yu, Hirst, Costa, Ng, Schiesser, Gertow, Stanley, Elefanty: APELIN promotes hematopoiesis from human embryonic stem cells. in Blood 2012 (PubMed)

  4. Hamster Monoclonal Apelin Receptor Primary Antibody for IHC, IHC (p) - ABIN4254280 : Cui, Mao, Yi, Wang, Zhang, Xie, Wu, Liao, Zhou, Meng, Yuan, Liao: Apelin suppresses apoptosis of human vascular smooth muscle cells via APJ/PI3-K/Akt signaling pathways. in Amino acids 2010 (PubMed)

More Antibodies against Apelin Receptor Interaction Partners

Cow (Bovine) Apelin Receptor (APLNR) interaction partners

  1. APJ receptor in granulosa cells and both apelin (show APLN Antibodies) and the APJ receptor in theca tissues are expressed in bovine ovary.

  2. The data suggest that apelin (show APLN Antibodies)/APJ system is involved in the mechanism regulating angiogenesis during follicle maturation as well as during corpora lutea formation and function in the bovine ovary.

Mouse (Murine) Apelin Receptor (APLNR) interaction partners

  1. the expression of APLNR (APJ/AGTRL1), the only known receptor for apelin (show APLN Antibodies), is predominantly restricted to the endothelial cells.

  2. The ELA-APJ axis protects from pressure overload-induced heart failure possibly via suppression of ACE (show ACE Antibodies) expression and pathogenic angiotensin II signaling.

  3. Internalization does not appear to contribute to the desensitization of APJ-mediated ppERK1/2 activation.

  4. the ELABELA (ELA)-APJ signaling axis is only required for sinus venosus-derived progenitors.

  5. These results demonstrate a new pharmacologic property of protamine-blockade of APJ-that could explain some adverse effects observed in protamine-treated patients, and that the established antiangiogenic activity of protamine would rely on APJ antagonism.

  6. Apelin (show APLN Antibodies)-36-[L28C(30kDa (show TAF10 Antibodies)-PEG (show PAEP Antibodies))] provides a starting point for the development of diabetes therapeutics that are devoid of the blood pressure effects associated with canonical APJ activation

  7. Results show that obese mice had significantly lower mRNA and protein expressions of apelin (show APLN Antibodies)/ APJ in skeletal muscles than the normal body weight mice.

  8. These results demonstrate that overexpression of APJ in cardiomyocytes has adverse effects on cardiac function in male and non-pregnant mice and that lactation contributes to the development of postpartum cardiomyopathy in the heart with APJ overexpression.

  9. Endothelial CXCR4 (show CXCR4 Antibodies) is negatively regulated by miR (show MLXIP Antibodies)-139-5p, whose transcription is in turn induced by laminar flow and APLN (show APLN Antibodies)/APLNR signalling.

  10. apelin (show APLN Antibodies) is produced by arterial endothelial cells (ECs) during embryogenesis, induces chemotaxis of venous ECs, and promotes the production of secreted Frizzled-related protein 1 (show SFRP1 Antibodies) by apelin receptor(+) ECs

Human Apelin Receptor (APLNR) interaction partners

  1. Apelin receptor signaling is critical for endothelial cell polarization.

  2. Studies indicate that the Elabela-APJ (apelin receptor) axis may protect against pressure overload-induced heart failure.

  3. The high APJ expression has significantly higher rates of tumor invasion, local lymph node, and distant metastasis (all p < 0.001).

  4. The mutation of polymorphism rs10501367 in APJ gene decreased risk of hypertension in Chinese males.

  5. these observations suggest apelin (show APLN Antibodies)-APJ signaling in hepatocytes functions to protect against lipid accumulation in liver through two signaling pathways, that is, via AMPK (show PRKAA1 Antibodies) activation and PPARalpha (show PPARA Antibodies) induction.

  6. 916 ischemic stroke patients were recruited for the study. For age at ischemic stroke onset, no significant association was identified with the variant rs9943582 of APLNR in any genetic model. In addition, the variant was not strongly associated with recurrence and death risk of ischemic stroke, as shown by the results.

  7. the expression of APLNR (APJ/AGTRL1), the only known receptor for apelin (show APLN Antibodies), is predominantly restricted to the endothelial cells.

  8. Studies suggest that apelin (show APLN Antibodies)/APJ system may be applied to the treatment of cancers by regulating apoptosis, which may play a vital role in anticancer therapy [review].

  9. Crystal structure of human APJR shows structural basis for apelin (show APLN Antibodies) recognition and binding

  10. mutation of promoter polymorphism rs7119375 in APJ gene was significantly associated with elevated SBP (show SHBG Antibodies) and increased hypertension risk in Chinese women.

Apelin Receptor (APLNR) Antigen Profile

Protein Summary

This gene encodes a member of the G protein-coupled receptor gene family. The encoded protein is related to the angiotensin receptor, but is actually an apelin receptor that inhibits adenylate cyclase activity and plays a counter-regulatory role against the pressure action of angiotensin II by exerting hypertensive effect. It functions in the cardiovascular and central nervous systems, in glucose metabolism, in embryonic and tumor angiogenesis and as a human immunodeficiency virus (HIV-1) coreceptor. Two transcript variants resulting from alternative splicing have been identified.

Gene names and symbols associated with anti-Apelin Receptor (APLNR) Antibodies

  • apelin receptor (APLNR) antibody
  • apelin receptor (aplnr) antibody
  • apelin receptor (Aplnr) antibody
  • Agtrl1 antibody
  • angio1 antibody
  • Apj antibody
  • APJR antibody
  • APLNR antibody
  • DKFZp469C1532 antibody
  • HG11 antibody
  • msr antibody
  • msr/apj antibody
  • X-msr antibody
  • Xangio1 antibody
  • Xmsr antibody

Protein level used designations for anti-Apelin Receptor (APLNR) Antibodies

angiotensin II receptor-like 1 , G-protein coupled receptor APJ , angiotensin receptor-like 1 , angiotensin receptor-related protein , apelin receptor , MSR , B78 , GPCR34 , APJ (apelin) receptor , APJ receptor , G protein-coupled receptor APJ , G-protein coupled receptor HG11 , HG11 orphan receptor

GENE ID SPECIES
483497 Canis lupus familiaris
466585 Pan troglodytes
613084 Xenopus (Silurana) tropicalis
615435 Bos taurus
100171470 Pongo abelii
100348126 Oryctolagus cuniculus
23796 Mus musculus
83518 Rattus norvegicus
187 Homo sapiens
706823 Macaca mulatta
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