anti-Apoptotic Chromatin Condensation Inducer 1 (ACIN1) Antibodies

Apoptosis is defined by several morphologic nuclear changes, including chromatin condensation and nuclear fragmentation. Additionally we are shipping ACIN1 Proteins (3) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
ACIN1 22985 Q9UKV3
ACIN1 56215 Q9JIX8
ACIN1 305884  
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Top anti-ACIN1 Antibodies at antibodies-online.com

Showing 10 out of 130 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Delivery Price Details
Cow Rabbit Un-conjugated WB Host: Rabbit Target Name: Acin1 Sample Type: Mouse Brain lysates Antibody Dilution: 1.0ug/ml 100 μL 2 to 3 Days
$289.00
Details
Cow Rabbit Un-conjugated WB Host: Rabbit Target Name: Acin1 Sample Type: Mouse Small Intestine Antibody Dilution: 1.0ug/ml 100 μL 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated ELISA, IHC, WB ABIN6271641 at 1/200 staining Human ganstric cancer tissue sections by IHC-P. The tissue was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The tissue was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary. ABIN6271641 at 1/200 staining Mouse brain tissue sections by IHC-P. The tissue was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The tissue was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary. 100 μL 11 to 12 Days
$450.00
Details
Human Rabbit Un-conjugated ELISA, ICC, IHC, IHC (p), WB Human Adrenal (formalin-fixed, paraffin-embedded) stained with ACIN1 antibody ABIN461881 at 5 ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. Human Pancreas (formalin-fixed, paraffin-embedded) stained with ACIN1 antibody ABIN461881 at 5 ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. 50 μg 11 to 14 Days
$616.00
Details
Human Rabbit Un-conjugated ELISA, ICC, IHC, IHC (p), WB Human Adrenal (formalin-fixed, paraffin-embedded) stained with ACIN1 antibody ABIN461879 at 5 ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. Human Small Intestine (formalin-fixed, paraffin-embedded) stained with ACIN1 antibody ABIN461879 at 5 ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. 0.05 mg 11 to 14 Days
$484.00
Details
Human Mouse Un-conjugated IP, WB 0.1 mg 6 to 8 Days
$401.50
Details
Human Rabbit Un-conjugated EIA, IF, IHC (p), WB Immunocytochemistry of Acinus in K562 cells with Acinus antibody at 5 µg/ml. Human Adrenal (formalin-fixed, paraffin-embedded) stained with ACIN1at 5 µg/ml followed by biotinylated goat anti-rabbit IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen. 50 μg 6 to 8 Days
$495.00
Details
Human Rabbit Un-conjugated IF (p), IHC (p) Formalin-fixed and paraffin embedded human cervical carcinoma labeled with Anti-phospho-Acinus(Ser1180) Polyclonal Antibody, Unconjugated (ABIN682708) at 1:200 followed by conjugation to the secondary antibody and DAB staining. Lane 1: mouse stomach lysates Lane 2: mouse pancreas lysates probed with Anti GRM1 Polyclonal Antibody, Unconjugated (ABIN682708) at 1:200 in 4 °C. Followed by conjugation to secondary antibody at 1:3000 90min in 37 °C. Predicted band 148kD. Observed band size: 148kD. 100 μL 3 to 7 Days
$339.90
Details
Human Rabbit Un-conjugated ELISA, WB Western blot analysis of ACINU using COS7 whole cell lysates 100 μL 11 to 12 Days
$390.77
Details
Human Rabbit Un-conjugated EIA, IF, IHC (p), WB Immunocytochemistry of Acinus in K562 cells with Acinus antibody at 0.5 µg/ml. Human Adrenal (formalin-fixed, paraffin-embedded) stained with ACIN1at 5 µg/ml followed by biotinylated goat anti-rabbit IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen. 50 μg 6 to 8 Days
$495.00
Details

Top referenced anti-ACIN1 Antibodies

  1. Human Polyclonal ACIN1 Primary Antibody for ICC, ELISA - ABIN1001732 : Zamzami, Kroemer: Condensed matter in cell death. in Nature 1999 (PubMed)
    Show all 2 Pubmed References

  2. Human Polyclonal ACIN1 Primary Antibody for ELISA, WB - ABIN1001733 : Sahara, Aoto, Eguchi, Imamoto, Yoneda, Tsujimoto: Acinus is a caspase-3-activated protein required for apoptotic chromatin condensation. in Nature 1999 (PubMed)
    Show all 2 Pubmed References

More Antibodies against ACIN1 Interaction Partners

Human Apoptotic Chromatin Condensation Inducer 1 (ACIN1) interaction partners

  1. ACIN1 mRNA was highly expressed in platelets of lung cancer patients

  2. We conclude that RNPS1 is a key factor for the quality control of mRNAs that is essential for the phenotypes including cell division.

  3. Genome-wide identification of RNA targets of Acinus revealed its role in splicing regulation as well as its involvement in other cellular pathways, including cell cycle progression.

  4. acinus L was identified as a potential novel mTORC1 target.

  5. Differences in the nuclear localization of Acinus-S' and Acinus-L may suggest that these two isoforms have different functional roles.

  6. the ligand-dependent splicing activity of Acinus is related to the retinoic acid-activated retinoic acid receptor

  7. An electronegative region on acinusS restricts SRPK2 phosphorylation to a single specific site.

  8. Chronic low-dose radiation increases the levels of AKT and acinus proteins via NF-kappaB activation

  9. Akt phosphorylation of acinus on serine 422 and 573 results in its resistance to caspase cleavage in the nucleus and the inhibition of acinus-dependent chromatin condensation.

  10. Acinus is not involved in DNA condensation but rather has a role in internucleosomal DNA cleavage during programmed cell death

  11. We found hypermethylation of the ACIN1 gene in early stage lung adenocarcinoma. The role of methylation status in the development and malignant transformation of lung adenocarcinoma requires clarification.

  12. identify Acinus-S' as a novel RAR-interacting protein[Acinus-S']

  13. The authors report here that AAC-11, a survival protein whose expression prevents apoptosis that occurs on deprivation of growth factors, physiologically binds to Acinus and prevents Acinus-mediated DNA fragmentation.

  14. A critical role for AKT activation in protecting cells from ionizing radiation-induced apoptosis and the regulation of acinus gene expression is reported.

  15. Study shows that transcription corepressor CtBP2 directly binds acinus, which is regulated by nerve growth factor (NGF), inhibiting its stimulatory effect on cyclin A1, but not cyclin A2, expression in leukemia.

Mouse (Murine) Apoptotic Chromatin Condensation Inducer 1 (ACIN1) interaction partners

  1. gp70 enhances cellular DNA-damage-induced signaling in association with host-specific cellular proteins including acinus and MCM2 resulting in the activation of DNA-PK to phosphorylate P53.

ACIN1 Antigen Profile

Protein Summary

Apoptosis is defined by several morphologic nuclear changes, including chromatin condensation and nuclear fragmentation. This gene encodes a nuclear protein that induces apoptotic chromatin condensation after activation by caspase-3, without inducing DNA fragmentation. This protein has also been shown to be a component of a splicing-dependent multiprotein exon junction complex (EJC) that is deposited at splice junctions on mRNAs, as a consequence of pre-mRNA splicing. It may thus be involved in mRNA metabolism associated with splicing. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Gene names and symbols associated with ACIN1

  • apoptotic chromatin condensation inducer 1b (acin1b) antibody
  • apoptotic chromatin condensation inducer 1a (acin1a) antibody
  • apoptotic chromatin condensation inducer 1 (acin1) antibody
  • apoptotic chromatin condensation inducer 1 (ACIN1) antibody
  • apoptotic chromatin condensation inducer 1 S homeolog (acin1.S) antibody
  • apoptotic chromatin condensation inducer 1 (Acin1) antibody
  • 2610036I19Rik antibody
  • 2610510L13Rik antibody
  • Acinus antibody
  • acinusa antibody
  • acinusb antibody
  • acinusL antibody
  • acinusS antibody
  • Acn antibody
  • C79325 antibody
  • fi14c05 antibody
  • fSAP152 antibody
  • ik:tdsubc_2g5 antibody
  • mKIAA0670 antibody
  • si:zc14a17.12 antibody
  • wu:fb04g06 antibody
  • wu:fb40f03 antibody
  • wu:fb68h03 antibody
  • wu:fb80f07 antibody
  • wu:fc12e10 antibody
  • wu:fe06a10 antibody
  • wu:fi14c05 antibody
  • xx:tdsubc_2g5 antibody

Protein level used designations for ACIN1

apoptotic chromatin condensation inducer in the nucleus, b , apoptotic chromatin condensation inducer in the nucleus, a , apoptotic chromatin condensation inducer 1 , apoptotic chromatin condensation inducer in the nucleus , apoptotic chromatin condensation inducer in the nucleus-like , functional spliceosome-associated protein 152 , acinus

GENE ID SPECIES
327495 Danio rerio
368893 Danio rerio
407918 Xenopus (Silurana) tropicalis
452792 Pan troglodytes
480247 Canis lupus familiaris
534600 Bos taurus
713310 Macaca mulatta
734979 Xenopus laevis
100338262 Oryctolagus cuniculus
100470890 Ailuropoda melanoleuca
100594211 Nomascus leucogenys
22985 Homo sapiens
56215 Mus musculus
305884 Rattus norvegicus
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