anti-ArfGAP with RhoGAP Domain, Ankyrin Repeat and PH Domain 1 (ARAP1) Antibodies

The protein encoded by ARAP1 contains SAM, ARF-GAP, RHO-GAP, ankyrin repeat, RAS-associating, and pleckstrin homology (PH) domains. Additionally we are shipping ARAP1 Proteins (4) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
ARAP1 69710 Q4LDD4
ARAP1 116985 Q96P48
ARAP1 361617  
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Top anti-ARAP1 Antibodies at antibodies-online.com

Showing 10 out of 51 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Delivery Price Details
Mouse Goat Un-conjugated ELISA, ICC, WB   100 μg 6 to 7 Days
$429.84
Details
Human Mouse Un-conjugated ICC, IP, WB Colocalization of ARAP1 with DR4 at the plasma membrane and in early endosomes. ARAP1-transfected NCTC cells were treated with TRAIL for 0, 30 or 60 and fixed with methanol. DR4 was detected by rabbit polyclonal (red) and ARAP1 with ARAP1-2 mouse monoclonal antibody (green). Arrowheads show ARAP1-DR4 colocalization at the plasma membrane and intracellular membranes, whereas arrows show their colocalization in early endosomes. 0.1 mg 5 to 7 Days
$428.84
Details
Human Rabbit Un-conjugated WB WB Image Sample (30 ug of whole cell lysate) A: H1299 5% SDS PAGE antibody diluted at 1:1000 100 μL 3 to 4 Days
$466.18
Details
Human Mouse Un-conjugated IF, IP, WB 0.1 mg 6 to 8 Days
$313.50
Details
Human Mouse Un-conjugated WB Western Blot analysis of ARAP1 expression in transfected 293T cell line by ARAP1 MaxPab polyclonal antibody.Lane 1: CENTD2 transfected lysate(132.55 KDa).Lane 2: Non-transfected lysate. 50 μL 11 to 12 Days
$440.00
Details
Dog Goat Un-conjugated ELISA   100 μg 11 to 14 Days
$610.50
Details
Human Rabbit Un-conjugated WB Western blot analysis of extracts of various cell lines, using ARAP1 antibody. 200 μL 12 to 14 Days
$438.90
Details
Human Rabbit Un-conjugated WB   100 μL 11 to 14 Days
$537.17
Details
Mouse Goat Biotin IC, ELISA, WB   100 μL 16 Days
$760.57
Details
Mouse Goat PE IC, ELISA, WB   100 μL 16 Days
$760.57
Details

Top referenced anti-ARAP1 Antibodies

  1. Human Monoclonal ARAP1 Primary Antibody for IF, IP - ABIN535240 : Kiger, Eklund, Younger, OKane: Transgenic inhibitors identify two roles for protein kinase A in Drosophila development. in Genetics 1999 (PubMed)
    Show all 3 Pubmed References

  2. Human Polyclonal ARAP1 Primary Antibody for IP, WB - ABIN261138 : Hasegawa, Tsujita, Takenawa, Itoh: ARAP1 regulates the ring size of circular dorsal ruffles through Arf1 and Arf5. in Molecular biology of the cell 2012 (PubMed)

  3. Human Monoclonal ARAP1 Primary Antibody for ICC, IP - ABIN302078 : Símová, Klíma, Cermak, Sourková, Andera: Arf and Rho GAP adapter protein ARAP1 participates in the mobilization of TRAIL-R1/DR4 to the plasma membrane. in Apoptosis : an international journal on programmed cell death 2008 (PubMed)
    Show all 3 Pubmed References

  4. Human Polyclonal ARAP1 Primary Antibody for ELISA - ABIN547166 : Miura, Jacques, Stauffer, Kubosaki, Zhu, Hirsch, Resau, Zheng, Randazzo: ARAP1: a point of convergence for Arf and Rho signaling. in Molecular cell 2002 (PubMed)

More Antibodies against ARAP1 Interaction Partners

Mouse (Murine) ArfGAP with RhoGAP Domain, Ankyrin Repeat and PH Domain 1 (ARAP1) interaction partners

  1. competitive analytical gel-filtration chromatography and isothermal titration calorimetry (ITC) results showed that ARAP1 could compete with Cbl for CIN85 binding, which provides a biochemical basis for the regulatory roles of ARAP1 in the CIN85-mediated EGFR internalizing process.

  2. Quantitative trait loci genes analysis reveals association between T2D risk variants at the ARAP1/STARD10 locus and STARD10 but not ARAP1 expression.

  3. Increased ARAP1 expression might contribute to type 2 diabetes susceptibility at this Genome-wide association studies locus.

  4. Arap1 is highly expressed in the renal vasculature, and its expression is suppressed by angiotensin II.

  5. afadin regulates the cyclical activation and inactivation of Rap1, Rac1, and RhoA through SPA-1 and ARAP1.

Human ArfGAP with RhoGAP Domain, Ankyrin Repeat and PH Domain 1 (ARAP1) interaction partners

  1. Quantitative trait loci genes analysis reveals association between T2D risk variants at the ARAP1/STARD10 locus and STARD10 but not ARAP1 expression.

  2. Genetic variant rs1552224 of CENTD2 on chromosome 11 contributes to an independent effect as well as joint cumulative effect with rs2237897 of KCNQ1 on the risk of type 2 diabetes mellitus in Chinese Han population.

  3. The proinsulin-decreasing and T2D-risk Alleles are associated with increased ARAP1 mRNA levels in primary human pancreatic islets.

  4. a novel molecular mechanism of circular dorsal ruffles ring size control through the ARAP1-Arf1/5 pathway.

  5. Arap1 is highly expressed in the renal vasculature, and its expression is suppressed by angiotensin II.

  6. Of the lead variants from 12 novel type 2 diabetes associated loci, CENTD2 significantly associated with increased plasma glucose values and decreased glucose-stimulated insulin release.

  7. ARAP1 associated with CIN85 affects epidermal growth factor receptor endocytic trafficking

  8. PTK6 enhances EGFR signaling by inhibition of EGFR down-regulation through phosphorylation of ARAP1 in breast cancer cells.

  9. ARAP1 acts primarily on Arf6 in vivo.

  10. ARAP1 knockdown significantly compromises the localization of death receptor 4 at the cell surface of several tumor cell lines and slows down their TRAIL-induced death.

  11. ARAP1 controls the late steps of the endocytic trafficking of the EGF-R

  12. ARAP1 regulates the endocytic traffic of EGFR and, consequently, the rate of EGFR signal attenuation

  13. Data suggest that ARAP1 is recruited to membranes independently of PtdIns(3,4,5)P(3), the subsequent production of which triggers enzymatic activity.

ARAP1 Antigen Profile

Protein Summary

The protein encoded by this gene contains SAM, ARF-GAP, RHO-GAP, ankyrin repeat, RAS-associating, and pleckstrin homology (PH) domains. In vitro, this protein displays RHO-GAP and phosphatidylinositol (3,4,5) trisphosphate (PIP3)-dependent ARF-GAP activity. The encoded protein associates with the Golgi, and the ARF-GAP activity mediates changes in the Golgi and the formation of filopodia. It is thought to regulate the cell-specific trafficking of a receptor protein involved in apoptosis. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with ARAP1

  • ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1 (ARAP1) antibody
  • centaurin, delta 2 (centd2) antibody
  • ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1 (Arap1) antibody
  • 2410002L19Rik antibody
  • ARAP1 antibody
  • Centd2 antibody
  • Ci-ArfGAP-8 antibody
  • mKIAA0782 antibody

Protein level used designations for ARAP1

centaurin delta 2 , centaurin, delta 2 , ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1 , arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1 , centaurin-delta-2 , cnt-d2 , ARF-GAP, RHO-GAP, ankyrin repeat, and pleckstrin homology domains-containing protein 1

GENE ID SPECIES
451406 Pan troglodytes
511889 Bos taurus
100014939 Monodelphis domestica
100052506 Equus caballus
100090045 Ornithorhynchus anatinus
100341403 Oryctolagus cuniculus
100511767 Sus scrofa
100594751 Nomascus leucogenys
100169677 Ciona intestinalis
485207 Canis lupus familiaris
69710 Mus musculus
116985 Homo sapiens
361617 Rattus norvegicus
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