ARAP1 antibody (AA 69-344)

Catalog No. ABIN7144564

Product Details anti-ARAP1 Antibody

Target: ARAP1 (ArfGAP with RhoGAP Domain, Ankyrin Repeat and PH Domain 1 (ARAP1))

Binding Specificity: AA 69-344

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ARAP1 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1 protein (69-344AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for ARAP1

Target: ARAP1 (ArfGAP with RhoGAP Domain, Ankyrin Repeat and PH Domain 1 (ARAP1))

Alternative Name: ARAP1 (ARAP1 Products)

Synonyms: CENTD2 antibody, ARAP1 antibody, Ci-ArfGAP-8 antibody, 2410002L19Rik antibody, Centd2 antibody, mKIAA0782 antibody, ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1 antibody, centaurin, delta 2 antibody, ARAP1 antibody, centd2 antibody, Arap1 antibody

Background:

Background: Phosphatidylinositol 3,4,5-trisphosphate-dependent GTPase-activating protein that modulates actin cytoskeleton remodeling by regulating ARF and RHO family members. Is activated by phosphatidylinositol 3,4,5-trisphosphate (PtdIns(3,4,5)P3) binding. Can be activated by phosphatidylinositol 3,4-bisphosphate (PtdIns(3,4,5)P2) binding, albeit with lower efficiency. Has a preference for ARF1 and ARF5 (By similarity).

Aliases: 2410002L19Rik antibody, ANK repeat and PH domain-containing protein 1 antibody, ARAP 1 antibody, Arap1 antibody, ARAP1_HUMAN antibody, Arf GAP Rho GAP ankyrin repeat and pleckstrin homology domains containing protein 1 antibody, Arf GAP Rho GAP ankyrin repeat and pleckstrin homology domain containing protein 1 antibody, Arf-GAP with Rho-GAP domain antibody, CENT D2 antibody, Centaurin delta 2 antibody, Centaurin delta2 antibody, Centaurin-delta-2 antibody, CENTD 2 antibody, CENTD2 antibody, Cnt d2 antibody, Cnt-d2 antibody, Cntd2 antibody, KIAA0782 antibody, MGC176140 antibody, mKIAA0782 antibody

UniProt: Q96P48