anti-ArfGAP with SH3 Domain, Ankyrin Repeat and PH Domain 3 (ASAP3) Antibodies

ASAP3 encodes a member of a subfamily of ADP-ribosylation factor(Arf) GTPase-activating proteins that contain additional ankyrin repeat and pleckstrin homology domains. Additionally we are shipping ArfGAP with SH3 Domain, Ankyrin Repeat and PH Domain 3 Proteins (4) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
ASAP3 55616 Q8TDY4
ASAP3 230837 Q5U464
ASAP3    
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Top anti-ArfGAP with SH3 Domain, Ankyrin Repeat and PH Domain 3 Antibodies at antibodies-online.com

Showing 10 out of 52 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Delivery Price Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-ASAP3 Antibody Titration: 0.2-1 ug/mlPositive Control: MCF7 cell lysate 100 μL 2 to 3 Days
$289.00
Details
Hamster Rabbit Un-conjugated EIA, IHC (p), WB ASAP3 antibody (N-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human hepatocarcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the ASAP3 antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated. ASAP3 Antibody (N-term) western blot analysis in CHO cell line lysates (35µg/lane).This demonstrates the ASAP3 antibody detected the ASAP3 protein (arrow). 0.4 mL 6 to 8 Days
$484.00
Details
Bat Rabbit Un-conjugated WB 100 μL 11 to 14 Days
$551.83
Details
Human Rabbit Un-conjugated IHC, IHC (p) 100 μg 11 to 14 Days
$507.83
Details
Hamster Rabbit Un-conjugated IHC (p), WB Western blot analysis in ZR-75-1 cell line lysates (35ug/lane). Western blot analysis in CHO cell line lysates (35ug/lane). 400 μL 2 to 3 Days
$515.63
Details
Human Rabbit Un-conjugated ELISA, WB 100 μg 11 to 14 Days
$639.83
Details
Human Mouse Un-conjugated WB Western Blot analysis of ASAP3 expression in transfected 293T cell line by ASAP3 MaxPab polyclonal antibody.Lane 1: DDEFL1 transfected lysate(99.33 KDa).Lane 2: Non-transfected lysate. 50 μL 11 to 12 Days
$440.00
Details
Human Rabbit Un-conjugated WB ASAP3 antibody used at 1 ug/ml to detect target protein. 50 μg 9 to 11 Days
$449.29
Details
Human Rabbit Un-conjugated EIA, WB   0.1 mg 11 Days
$632.50
Details
Human Rabbit Un-conjugated WB 100 μg 2 to 3 Days
$258.46
Details

Top referenced anti-ArfGAP with SH3 Domain, Ankyrin Repeat and PH Domain 3 Antibodies

  1. Human Polyclonal ASAP3 Primary Antibody for IHC (fro), ELISA - ABIN539512 : Okabe, Furukawa, Kato, Hasegawa, Yamaoka, Nakamura: Isolation of development and differentiation enhancing factor-like 1 (DDEFL1) as a drug target for hepatocellular carcinomas. in International journal of oncology 2003 (PubMed)
    Show all 3 Pubmed References

  2. Human Polyclonal ASAP3 Primary Antibody for ELISA, WB - ABIN233800 : Luo, Kong, Wang, Chen, Liu, Wang, Xu, Wang, Yang: Loss of ASAP3 destabilizes cytoskeletal protein ACTG1 to suppress cancer cell migration. in Molecular medicine reports 2014 (PubMed)

More Antibodies against ArfGAP with SH3 Domain, Ankyrin Repeat and PH Domain 3 Interaction Partners

Human ArfGAP with SH3 Domain, Ankyrin Repeat and PH Domain 3 (ASAP3) interaction partners

  1. ARF6 GTPase-activating protein ACAP4 regulates CCL18-elicited breast cancer cell migration via the acetyltransferase PCAF-mediated acetylation. CCL18 stimulation elicited breast cancer cell migration and invasion via PCAF-dependent acetylation.

  2. MiR-143-3p acts as an anti-oncogene by downregulating ITGA6/ASAP3 protein expression and could offer new insight into potential therapeutic targets for CRC.

  3. Results show that ASAP3 was amplified in colorectal cancer (CRC) tissues, and its upregulation was associated with poor prognosis of patients with CRC. Also, it promoted growth of colon tumors, and accelerated cell invasion and migration through its binding to NEMO. These results suggest that ASAP3 acts as an oncogene.

  4. The data, for the first time, link ASAP3 with ACTG1 in the regulation of cytoskeletal maintenance and cell motility

  5. ). These data indicate that ASAP3 is elevated in NSCLC and may contribute to cancer development and patients' poor clinical outcome, which is possibly due to its critical roles in regulating cancer invasion.

  6. Phosphorylation of the N-terminal region of ACAP4 (named the Bin, Amphiphysin, and RSV161/167[BAR] domain at Tyr34) is necessary for epidermal growth factor (EGF)-elicited membrane remodeling.

  7. ACAP4 protein cooperates with Grb2 protein to orchestrate epidermal growth factor-stimulated integrin beta1 recycling in cell migration

  8. The ArfGAP catalytic mechanism and shows a glutamine from Arf6 and an arginine fingerASAP3 as the important catalytic residues; unexpectedly the structure shows a calcium ion, liganded by both proteins in the complex interface.

  9. ACAP4 is involved in ARF6-mediated cell migration.

  10. ASAP3 functions nonredundantly with ASAP1 to control cell movement and may have a role in cancer cell invasion.

Mouse (Murine) ArfGAP with SH3 Domain, Ankyrin Repeat and PH Domain 3 (ASAP3) interaction partners

  1. ASAP3 functions nonredundantly with ASAP1 to control cell movement and may have a role in cancer cell invasion.

ArfGAP with SH3 Domain, Ankyrin Repeat and PH Domain 3 (ASAP3) Antigen Profile

Protein Summary

This gene encodes a member of a subfamily of ADP-ribosylation factor(Arf) GTPase-activating proteins that contain additional ankyrin repeat and pleckstrin homology domains. The Arf GAP domain of this protein catalyzes the hydrolysis of GTP bound to Arf proteins. The encoded protein promotes cell differentiation and migration and has been implicated in cancer cell invasion. Alternative splicing results in multiple transcript variants.

Gene names and symbols associated with ASAP3

  • ArfGAP with SH3 domain, ankyrin repeat and PH domain 3 (ASAP3) antibody
  • ArfGAP with SH3 domain, ankyrin repeat and PH domain 3 (asap3) antibody
  • development and differentiation enhancing factor-like 1 (DDEFL1) antibody
  • ArfGAP with SH3 domain, ankyrin repeat and PH domain 3 (Asap3) antibody
  • 9430088F20Rik antibody
  • ACAP4 antibody
  • CENTB6 antibody
  • Ddefl1 antibody
  • Gm140 antibody
  • UPLC1 antibody
  • zgc:113885 antibody

Protein level used designations for ASAP3

ArfGAP with SH3 domain, ankyrin repeat and PH domain 3 1 , development and differentiation enhancing factor-like 1 , ArfGAP with SH3 domain, ankyrin repeat and PH domain 3 , ARF6 GTPase-activating protein , arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 3 , centaurin, beta 6 , development and differentiation-enhancing factor-like 1 , protein up-regulated in liver cancer 1 , up-regulated in liver cancer 1 (UPLC1)

GENE ID SPECIES
456617 Pan troglodytes
664764 Danio rerio
769389 Gallus gallus
100071599 Equus caballus
100548261 Meleagris gallopavo
100553150 Anolis carolinensis
100583081 Nomascus leucogenys
55616 Homo sapiens
230837 Mus musculus
487377 Canis lupus familiaris
100626125 Sus scrofa
523797 Bos taurus
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