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ASPN encodes a cartilage extracellular protein that is member of the small leucine-rich proteoglycan family. Additionally we are shipping Asporin Antibodies (59) and Asporin Proteins (7) and many more products for this protein.
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This gene encodes a cartilage extracellular protein that is member of the small leucine-rich proteoglycan family. The encoded protein may regulate chondrogenesis by inhibiting transforming growth factor-beta 1-induced gene expression in cartilage. This protein also binds collagen and calcium and may induce collagen mineralization. Polymorphisms in the aspartic acid repeat region of this gene are associated with a susceptibility to osteoarthritis. Alternate splicing results in multiple transcript variants.
asporin (LRR class 1)
, asporin proteoglycan
, periodontal ligament associated protein 1
, small leucine-rich protein 1C
, biglycan-like protein 3
, periodontal ligament-associated protein 1