anti-ATXN7 Antibodies

The autosomal dominant cerebellar ataxias (ADCA) are a heterogeneous group of neurodegenerative disorders characterized by progressive degeneration of the cerebellum, brain stem and spinal cord.

Data Quality
  • 1
  • 6
Type
  • 50
    Primary
Target
  • 50
    Ataxin 7 (ATXN7)
  • 1412
  • 1234
  • 1168
  • 928
Application
  • 35
  • 22
  • 13
  • 3
  • 3
Reactivity
  • 49
  • 26
  • 23
  • 3
  • 3
Host
  • 47
  • 3
Clonality
  • 47
  • 3
Clone
  • 1
  • 1
Binding Specificity
  • 9
  • 9
  • 8
  • 7
  • 4
Conjugate
  • 19
  • 5
  • 4
  • 4
  • 2
Isotype
  • 35
  • 2
  • 2
  • 1
  • 1
Format
  • 45
  • 3
Suggested next Filters
50 Products
ReactivityChicken, Dog, Human, Mouse, Rat
Application WB
Order details Cat. No. ABIN927440
$517.86
50 μg
Plus shipping costs $45.00
Delivery in 9 to 11 Business Days
ReactivityCow, Dog, Guinea Pig, Horse, Human, Mouse, Pig, Rabbit, Rat
Application WB
Order details Cat. No. ABIN2777891
$229.00
100 μL
Plus shipping costs $45.00
Delivery in 2 to 3 Business Days
Rabbit, Polyclonal, IgG
ReactivityHuman, Mouse
Application ELISA, IHC, WB
Order details Cat. No. ABIN6260150
$390.77
Plus shipping costs $45.00
Delivery in 11 to 12 Business Days
ReactivityCow, Dog, Guinea Pig, Human, Mouse, Rabbit, Rat
Application WB
Order details Cat. No. ABIN2780337
$229.00
100 μL
Plus shipping costs $45.00
Delivery in 2 to 3 Business Days
ReactivityHuman, Mouse, Rat
Application WB
Order details Cat. No. ABIN2705522
$487.50
200 μL
Plus shipping costs $45.00
Delivery in 13 to 14 Business Days
ReactivityGuinea Pig, Horse, Human, Monkey, Mouse
Application WB
Order details Cat. No. ABIN6742371
$551.83
100 μL
Plus shipping costs $45.00
Delivery in 11 to 14 Business Days
ReactivityHuman
Application WB
Order details Cat. No. ABIN2441642
$318.55
100 μL
Plus shipping costs $45.00
Delivery in 2 to 3 Business Days
Rabbit, Polyclonal, IgG
ReactivityHuman, Mouse, Rat
Application IF (p), IHC (p), WB
Order details Cat. No. ABIN1386510
$327.80
100 μL
Plus shipping costs $45.00
Delivery in 3 to 7 Business Days
ReactivityHuman, Mouse, Rat
Application WB
Order details Cat. No. ABIN2589474
$375.83
100 μL
Plus shipping costs $45.00
Delivery in 11 to 14 Business Days
Mouse, Monoclonal (3SCA-1C1), IgG1, kappa
ReactivityHuman, Mouse
Application IC, ELISA, WB
Order details Cat. No. ABIN2853652
$381.15
100 μL
Plus shipping costs $45.00
Delivery in 7 to 8 Business Days
Rabbit, Polyclonal, IgG
ReactivityHuman, Mouse, Rat
Application IHC (p), WB
Order details Cat. No. ABIN1390561
$407.00
100 μL
Plus shipping costs $45.00
Delivery in 14 to 21 Business Days
Rabbit, Polyclonal, IgG
ReactivityHuman, Mouse, Rat
Application IF (p)
Order details Cat. No. ABIN1408449
$430.10
100 μL
Plus shipping costs $45.00
Delivery in 14 to 21 Business Days
Rabbit, Polyclonal, IgG
ReactivityHuman, Mouse, Rat
Application IHC (p), WB
Order details Cat. No. ABIN1408454
$430.10
100 μL
Plus shipping costs $45.00
Delivery in 14 to 21 Business Days
Rabbit, Polyclonal, IgG
ReactivityHuman, Mouse, Rat
Application IF (p)
Order details Cat. No. ABIN1408452
$430.10
100 μL
Plus shipping costs $45.00
Delivery in 14 to 21 Business Days
Rabbit, Polyclonal, IgG
ReactivityHuman, Mouse, Rat
Application IF (p)
Order details Cat. No. ABIN1408451
$430.10
100 μL
Plus shipping costs $45.00
Delivery in 14 to 21 Business Days
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ATXN7 Antigen Profile

Protein Summary

The autosomal dominant cerebellar ataxias (ADCA) are a heterogeneous group of neurodegenerative disorders characterized by progressive degeneration of the cerebellum, brain stem and spinal cord. Clinically, ADCA has been divided into three groups: ADCA types I-III. ADCAI is genetically heterogeneous, with five genetic loci, designated spinocerebellar ataxia (SCA) 1, 2, 3, 4 and 6, being assigned to five different chromosomes. ADCAII, which always presents with retinal degeneration (SCA7), and ADCAIII often referred to as the 'pure' cerebellar syndrome (SCA5), are most likely homogeneous disorders. Several SCA genes have been cloned and shown to contain CAG repeats in their coding regions. ADCA is caused by the expansion of the CAG repeats, producing an elongated polyglutamine tract in the corresponding protein. The expanded repeats are variable in size and unstable, usually increasing in size when transmitted to successive generations. This locus has been mapped to chromosome 3, and it has been determined that the diseased allele associated with spinocerebellar ataxia-7 contains 38-130 CAG repeats (near the N-terminus), compared to 7-17 in the normal allele. The encoded protein is a component of the SPT3/TAF9/GCN5 acetyltransferase (STAGA) and TBP-free TAF-containing (TFTC) chromatin remodeling complexes, and it thus plays a role in transcriptional regulation. Alternative splicing results in multiple transcript variants.

Gene names and symbols associated with anti-Ataxin 7 (ATXN7) Antibodies

  • ataxin 7 L homeolog (atxn7.L) antibody
  • ataxin 7 (atxn7) antibody
  • ataxin 7 (ATXN7) antibody
  • ataxin 7 (Atxn7) antibody
  • A430107N12Rik antibody
  • ADCAII antibody
  • AI627028 antibody
  • ataxin-7 antibody
  • MGC82940 antibody
  • OPCA3 antibody
  • RGD1562692 antibody
  • Sca7 antibody

Protein level used designations for anti-Ataxin 7 (ATXN7) Antibodies

ataxin 7 , ataxin-7 , spinocerebellar ataxia type 7 protein , spinocerebellar ataxia 7 homolog , spinocerebellar ataxia type 7 protein homolog

GENE ID SPECIES
444398 Xenopus laevis
100127691 Xenopus (Silurana) tropicalis
6314 Homo sapiens
246103 Mus musculus
361015 Rattus norvegicus
416078 Gallus gallus
484701 Canis lupus familiaris
100519688 Sus scrofa
536833 Bos taurus