anti-Butyrophilin-Like 2 (MHC Class II Associated) (BTNL2) Antibodies

Negative regulator of T-cell proliferation.. Additionally we are shipping BTNL2 Proteins (8) and BTNL2 Kits (6) and many more products for this protein.

Gene Name	GeneID	UniProt
BTNL2	56244	Q9UIR0
BTNL2	309620
BTNL2	547431	O70355

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Top anti-BTNL2 Antibodies at antibodies-online.com

Showing 10 out of 19 products:

Catalog No.	Reactivity	Host	Conjugate	Application	Quantity	Supplier	Delivery	Price	Details
ABIN1386835	Human	Rabbit	Un-conjugated	IF (p), IHC (p)	100 μL	Log in to see	3 to 7 Days	$306.90	Details
ABIN2561480	Human	Rabbit	Un-conjugated	IHC, WB	100 μL	Log in to see	16 Days	$334.77	Details
ABIN2883148	Human	Rabbit	Un-conjugated	IHC, WB	50 μL	Log in to see	7 to 9 Days	$361.17	Details
ABIN6004712	Human	Rabbit	Un-conjugated	WB	100 μL	Log in to see	11 to 18 Days	$369.55	Details
ABIN3048111	Human	Rabbit	Un-conjugated	WB	100 μL	Log in to see	11 to 16 Days	$426.40	Details
ABIN6293295	Human	Rabbit	Un-conjugated	WB	50 μL	Log in to see	16 Days	$269.95	Details
ABIN6082110	Human	Rabbit	HRP	ELISA	100 μg	Log in to see	11 to 18 Days	$668.03	Details
ABIN6082112	Human	Rabbit	FITC	ELISA	100 μg	Log in to see	11 to 18 Days	$668.03	Details
ABIN6082114	Human	Rabbit	Biotin	ELISA	100 μg	Log in to see	11 to 18 Days	$668.03	Details
ABIN6098175	Human	Rabbit	Un-conjugated	ELISA, IHC, WB	100 μL	Log in to see	11 to 18 Days	$440.62	Details

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More Antibodies against BTNL2 Interaction Partners

Human Butyrophilin-Like 2 (MHC Class II Associated) (BTNL2) interaction partners

Host-genotype analysis revealed an association of the rs2076530 (BTNL2) risk allele with a decrease in bacterial burden in sarcoidosis.
HLA-DPB1 (show HLA-DPB1 Antibodies)*05:01 gene was associated with the geographical region of PV and the BTNL2 gene was significantly associated with family history and age of onset of PV. In conclusion, the HLA-DPB1 (show HLA-DPB1 Antibodies)*05:01 and BTNL2 genes might be responsible for the complicacy of clinical features.
The sarcoidosis risk variant BTNL2 c.1078G.A (rs2076530) was associated with disease in all OFG cases (P (1/4) 0.013; OR (1/4) 1.33; 95% CI, 1.06-1.67) and had a similar OR (1.56) and the same direction of effect as seen in sarcoidosis. However, no association was seen for the subphenotypes of OFG only or OFG+CD.
Despite a significant difference in BTNL2 polymorphism between sarcoid patients and controls, there was no such difference between familial and sporadic sarcoidosis cases and no correlation between BTNL2 polymorphism and disease severity or outcome. Thus, BTNL2 difference cannot be considered as a key marker for disease classification or patient management.
Two new signals were observed at genome-wide significance (P < 5 x 10-8), namely, rs7216064 (17q24.3, BPTF (show BPTF Antibodies)), for overall lung adenocarcinoma risk, and rs3817963 (6p21.3, BTNL2) which is specific to cases with EGFR (show EGFR Antibodies) mutations. In further sub-analyses by EGFR (show EGFR Antibodies) status, rs9387478 (ROS1 (show ROS1 Antibodies)/DCBLD1) and rs2179920 (HLA-DPB1 (show HLA-DPB1 Antibodies)) showed stronger estimated associations in EGFR (show EGFR Antibodies)-positive compared to EGFR (show EGFR Antibodies)-negative cases
BTNL2 variant is associated with psoriasis.
Butyrophilin-like 2, expressed at various levels by UM cells and macrophages, might interfere with the immune control of the tumor. Butyrophilin-like 2 variants showed highly variable frequencies among ethnically related cohorts. There was no enrichment of BTNL2 variants in patients with UM compared with control patients.
BTNL2 G16071A gene polymorphism may as a likelihood factor contributed to granulomatous disease susceptibility, especially increasing the sarcoidosis susceptibility. In addition, the polymorphism may be greatly associated with likelihood of granulomatous diseases among Caucasians.
BTNL2 may have an inhibitory effect on FOXP3 (show FOXP3 Antibodies)(+) T cell proliferation, especially in patients homozygous for the risk alleles.
genetic mutations within or around BTNL2 (rs3763313, rs9268494, rs9268492 and rs9268402) could alter susceptibility to grade IV of dilated cardiomyopathy in a Chinese population

Mouse (Murine) Butyrophilin-Like 2 (MHC Class II Associated) (BTNL2) interaction partners

Butyrophilin-like 2 modulates B7 costimulation to induce Foxp3 (show FOXP3 Antibodies) expression and regulatory T cell development in mature T cells.
BTNL2 is overexpressed during both the asymptomatic and symptomatic phase of the Mdr1a (show ABCB4 Antibodies) knockout model of spontaneous colitis. Soluble BTNL2-Fc protein inhibits proliferation of murine T4 cells from the spleen, mesenteric lymph node, and Peyer's patch.

BTNL2 Antigen Profile

Protein Summary

Negative regulator of T-cell proliferation.

Gene names and symbols associated with BTNL2

butyrophilin like 2 (BTNL2) antibody
butyrophilin-like 2 (Btnl2) antibody
butyrophilin-like 2 (MHC class II associated) (BTNL2) antibody
butyrophilin-like protein 2 (LOC100348151) antibody

BTL-II antibody
Btl2 antibody
BTLN2 antibody
BTNL2 antibody
Gm315 antibody
HSBLMHC1 antibody
NG9 antibody
SS2 antibody

Protein level used designations for BTNL2

butyrophilin-like protein 2 , butyrophylin-like MHC class II associated , butyrophilin-like 2 (MHC class II associated) , butyrophilin-like protein 2-like

GENE ID	SPECIES
56244	Homo sapiens
309620	Rattus norvegicus
481730	Canis lupus familiaris
547431	Mus musculus
745506	Pan troglodytes
789224	Bos taurus
100051881	Equus caballus
100348151	Oryctolagus cuniculus
100441854	Pongo abelii
100158014	Sus scrofa

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