BTNL2 antibody
Quick Overview for BTNL2 antibody (ABIN7073240)
Target
See all BTNL2 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Cross-Reactivity
- Human, Rat
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Purification
- Affinity purification
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Immunogen
- Recombinant protein corresponding to Mouse BTNL2
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Application Notes
- WB (H,M,R) 1:500-1:1000
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS, pH 7.4, 0.02 % sodium azide
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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- BTNL2 (Butyrophilin-Like 2 (MHC Class II Associated) (BTNL2))
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Alternative Name
- BTNL2
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Background
- BTNL2 (butyrophilin-like protein 2), also known as BTL-II, is a 455 amino acid single-pass type II membrane protein that acts as a negative regulator of T cell proliferation. BTNL2 exists as at least six alternatively spliced isoforms, which are encoded by a gene located on human chromosome 6. Expression of BTNL2 isoform 3 is associated with susceptibility to sarcoidosis type 2 (SS2), an immune disorder that causes chronic inflammatory granulomatous lesions.
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Molecular Weight
- 65 kDa
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Gene ID
- 547431
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NCBI Accession
- NP_524574
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UniProt
- O70355
Target
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