CD320 Molecule Proteins (CD320)

CD320 encodes the transcobalamin receptor that is expressed at the cell surface. Additionally we are shipping CD320 Antibodies (58) and CD320 Kits (43) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
CD320 51293 Q9NPF0
CD320 54219 Q9Z1P5
CD320 362851 Q5HZW5
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Top CD320 Proteins at antibodies-online.com

Showing 10 out of 31 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 50 to 55 Days
$5,262.31
Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
$6,749.58
Details
Human Cells Mouse His tag 100 μg Log in to see 14 to 16 Days
$440.65
Details
Escherichia coli (E. coli) Human GST tag CD320 Molecule (CD320) (AA 36-231), (partial) protein (GST tag) 50 μg Log in to see 13 to 16 Days
$242.00
Details
Human Cells Human His tag   50 μg Log in to see 4 Days
$313.50
Details
Human Cells Mouse Fc Tag 100 μg Log in to see 14 to 16 Days
$440.65
Details
Baculovirus infected Insect Cells Human hIgG-His-tag 50 μg Log in to see 13 to 16 Days
$400.00
Details
Escherichia coli (E. coli) Human GST tag 100 μg Log in to see 11 Days
$411.40
Details
Wheat germ Human GST tag 10 μg Log in to see 11 to 12 Days
$414.29
Details
Human Cells Human Fc Tag   10 μg Log in to see 15 to 16 Days
$212.50
Details

CD320 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , , , , ,
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Mouse (Murine) ,
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Rat (Rattus) ,
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More Proteins for CD320 Molecule (CD320) Interaction Partners

Human CD320 Molecule (CD320) interaction partners

  1. A known pathogenic CD320 variant (c.262_264GAG; p.Glu88del) in methylmalonic aciduria cases.

  2. It has been proposed that the transcobalamin 2 receptor (TCN2R) is associated with idiopathic recurrent spontaneous abortion (RSA). The findings showed no significant association between TCN2R rs2336573 polymorphisms and the risk/protection of recurrent spontaneous abortion.

  3. the crystal structure of human holo-transcobalamin (TC) in complex with the extracellular domain of CD320, visualizing the structural basis of the TC-CD320 interaction, is reported.

  4. There was no significant difference in the expression of soluble csf CD320 between patients and controls.

  5. Although not significant when corrected for multiple testing, eight single nucleotide polymorphisms (SNPs) in two genes, transcobalamin II (TCN2) and the transcobalamin II-receptor (TCblR), were found to influence several clinical traits of cobalamin deficiency.

  6. The soluble transcobalamin receptor is present in cerebrospinal fluid and correlates to dementia-related biomarkers tau proteins and amyloid-beta.

  7. Transcobalamin II (TCN2 67A>G and TCN2 776C>G) and transcobalamin II receptor (TCblR 1104C>T) polymorphisms in Korean patients with idiopathic recurrent spontaneous abortion

  8. The high urinary concentration and the strong correlation between urinary and serum sCD320 suggests that sCD320 is filtered in the kidney.

  9. Data indicate that only the extracellular region (aa 32-229) of TCblR/CD320 is needed for transcobalamin-cobalamin (TC-Cbl) binding.

  10. Proliferating cancer cells express measurable levels of TCII and TCII-R.

  11. TCblr SNP were associated with omphalocele suggests that disruption of methylation reactions, in which folate, vitamin B12, and homocysteine play critical parts, may be a risk factor for omphalocele.

  12. Our data suggest that variation in TCblR plays a role in neural tube defect risk and that these variants may modulate cobalamin metabolism.

  13. the cell cycle associated expression of TCblR appears to be tightly regulated in synchrony with the proliferative phase of the cell cycle.

  14. Analysis of TCblR/CD320, the gene for the receptor for cellular uptake of transcobalamin-bound cobalamin, identified a homozygous single codon deletion, c.262_264GAG (p.E88del), resulting in the loss of a glutamic acid residue.

  15. Confocal microscopy of tonsil sections revealed co-localization of CD320 with CD19 and CD38 but not with CD3 indicating that germinal center B cells expressed CD320 in addition to follicular dendritic cells.

  16. This gene encodes a receptor for cellular uptake of transcobalamin-bound vitamin B12.

Mouse (Murine) CD320 Molecule (CD320) interaction partners

  1. An alternative mechanism exists for mice to transport cobalamin independent of the Cd320 encoded receptor.

  2. This study evaluated the role of transcobalamin (TC), the transcobalamin receptor (CD320) , and megalin in various tissues during pregnancy.

  3. CD320 role in the hippocampal long-term potentiation and the hippocampal pyramidal neurons.

  4. Severe cobalamin depletion in the central nervous system (CNS) after birth in TCblR knockouts indicates that TCblR is the only receptor responsible for cobalamin uptake in the CNS

  5. In vivo, endogenous PCSK9 regulates VLDLR protein levels and triglyceride accumulation in adipose tissue.

  6. Diabetic rats showed severe hyperlipidemia on d 21 and 28, with a dramatic decline in VLDL-R protein in skeletal muscle (>90%), heart (approximately 50%) and a loss of adipose tissues itself.

  7. Reelin binds several receptors, including the VLDL receptor in cultured hippocampus neurons.

  8. VLDL and LDL lowering by gene transfer of the VLDL receptor combined with a low-fat diet regimen induces regression and reduces macrophage content in advanced atherosclerotic lesions in LDL receptor-deficient mice

  9. These data demonstrate a cell-autonomous function of ApoER2, and most likely VLDLR and Dab1, in postnatal migration of neuroblasts in the forebrain, which is suggested to depend on ligands other than Reelin.

  10. The high affinity of apoE4 to the LDLR enhances VLDL sequestration on the hepatocyte surface but delays their internalization.

  11. Data show that thrombospondin-1 (THBS-1) is a novel physiological ligand for ApoER2 and VLDLR, and that lack of THBS-1 results in anatomical abnormalities of the RMS and leads to a reduction of postnatal neuronal precursors entering the OB.

CD320 Protein Profile

Protein Summary

This gene encodes the transcobalamin receptor that is expressed at the cell surface. It mediates the cellular uptake of transcobalamin bound cobalamin (vitamin B12), and is involved in B-cell proliferation and immunoglobulin secretion. Mutations in this gene are associated with methylmalonic aciduria. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with CD320 Molecule Proteins (CD320)

  • CD320 molecule (CD320)
  • CD320 antigen (Cd320)
  • CD320 molecule (Cd320)
  • 8D6 protein
  • 8D6A protein
  • 425O18-1 protein
  • D17Ertd716e protein
  • NG29 protein
  • RGD1305860 protein
  • TCblR protein
  • VLDL protein

Protein level used designations for CD320 Molecule Proteins (CD320)

8D6 antigen , CD320 antigen , FDC-SM-8D6 , FDC-signaling molecule 8D6 , transcobalamin receptor , TCblR , putative VLDL lipoprotein receptor , CD320 molecule

GENE ID SPECIES
51293 Homo sapiens
54219 Mus musculus
362851 Rattus norvegicus
456436 Pan troglodytes
476721 Canis lupus familiaris
505043 Bos taurus
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