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CD320 Protein (AA 36-231) (Fc Tag)

CD320 Origin: Human Host: Human Cells Recombinant > 95 % as determined by reducing SDS-PAGE.
Catalog No. ABIN1691726
  • Target See all CD320 Proteins
    CD320 (CD320 Molecule (CD320))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 36-231
    Origin
    • 9
    • 1
    • 1
    Human
    Source
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human Cells
    Purification tag / Conjugate
    This CD320 protein is labelled with Fc Tag.
    Purpose
    Recombinant Human Transcobalamin II Receptor/TCblR/8D6A/CD320 (C-Fc)
    Sequence
    SPLSTPTSAQ AAGPSSGSCP PTKFQCRTSG LCVPLTWRCD RDLDCSDGSD EEECRIEPCT QKGQCPPPPG LPCPCTGVSD CSGGTDKKLR NCSRLACLAG ELRCTLSDDC IPLTWRCDGH PDCPDSSDEL GCGTNEILPE GDATTMGPPV TLESVTSLRN ATTMGPPVTL ESVPSVGNAT SSSAGDQSGS PTAYGVVDDI EGRMDEPKSC DKTHTCPPCP APELLGGPSV FLFPPKPKDT LMISRTPEVT CVVVDVSHED PEVKFNWYVD GVEVHNAKTK PREEQYNSTY RVVSVLTVLH QDWLNGKEYK CKVSNKALPA PIEKTISKAK GQPREPQVYT LPPSREEMTK NQVSLTCLVK GFYPSDIAVE WESNGQPENN YKTTPPVLDS DGSFFLYSKL TVDKSRWQQG NVFSCSVMHE ALHNHYTQKS LSLSPGK
    Characteristics

    Recombinant Human Transcobalamin II Receptor/TCblR/8D6A/CD320 (C-Fc)

    Purity
    > 95 % as determined by reducing SDS-PAGE.
    Sterility
    0.2 μm filtered
    Endotoxin Level
    Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
    Top Product
    Discover our top product CD320 Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    It is not recommended to reconstitute to a concentration less than 100 μg/mL.
    Dissolve the lyophilized protein in ddH2O.
    Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
    Buffer
    Lyophilized from a 0.2 μm filtered solution of 20 mM Tris,150 mM NaCl, pH 8.0.
    Handling Advice
    Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
    Storage
    4 °C/-20 °C/-80 °C
    Storage Comment
    Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
    Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
    Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • Target
    CD320 (CD320 Molecule (CD320))
    Alternative Name
    CD320 (CD320 Products)
    Synonyms
    8D6 Protein, 8D6A Protein, TCBLR Protein, 425O18-1 Protein, D17Ertd716e Protein, NG29 Protein, VLDL Protein, RGD1305860 Protein, TCblR Protein, CD320 molecule Protein, CD320 antigen Protein, CD320 Protein, Cd320 Protein
    Background
    Recombinant Human CD320/TCblR/8D6A is produced by our mammalian expression system in human cells. The target protein is expressed with sequence (Ser36-Val231) of Human CD320 fused with a FC tag at the C-terminus.
    CD320 antigen is also known as 8D6 antigen, FDC-signaling molecule 8D6, Transcobalamin receptor and 8D6A. It is a single-pass type I membrane protein and containing two LDL-receptor class A domains. CD320 has been recently discovered and reported as a follicular dendritic cell (FDC) protein. CD320 can augments the proliferation of plasma cells precursors generated by IL-10. CD320 also founctions a receptor for the cellular uptake of transcobalamin bound cobalamin. Defects in CD320 are the cause of methylmalonic aciduria type TCblR (MMATC) which is a metabolic disorder.
    Molecular Weight
    47.3 kDa
    UniProt
    Q9NPF0
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