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The protein encoded by CD99 is a cell surface glycoprotein involved in leukocyte migration, T-cell adhesion, ganglioside GM1 and transmembrane protein transport, and T-cell death by a caspase-independent pathway. Additionally we are shipping CD99 Kits (37) and CD99 Proteins (29) and many more products for this protein.
Showing 10 out of 449 products:
Human Monoclonal CD99 Primary Antibody for FACS - ABIN2749207
Waclavicek, Majdic, Stulnig, Berger, Sunder-Plassmann, Zlabinger, Baumruker, Stöckl, Ebner, Knapp, Pickl: CD99 engagement on human peripheral blood T cells results in TCR/CD3-dependent cellular activation and allows for Th1-restricted cytokine production. in Journal of immunology (Baltimore, Md. : 1950) 1998
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Human Monoclonal CD99 Primary Antibody for FACS - ABIN2689467
Aussel, Bernard, Breittmayer, Pelassy, Zoccola, Bernard: Monoclonal antibodies directed against the E2 protein (MIC2 gene product) induce exposure of phosphatidylserine at the thymocyte cell surface. in Biochemistry 1993
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Human Monoclonal CD99 Primary Antibody for FACS - ABIN1027669
Kueng, Leb, Haiderer, Raposo, Thery, Derdak, Schmetterer, Neunkirchner, Sillaber, Seed, Pickl: General strategy for decoration of enveloped viruses with functionally active lipid-modified cytokines. in Journal of virology 2007
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Human Monoclonal CD99 Primary Antibody for FACS - ABIN1027667
Brémond, Meynet, Mahiddine, Coito, Tichet, Scotlandi, Breittmayer, Gounon, Gleeson, Bernard, Bernard: Regulation of HLA class I surface expression requires CD99 and p230/golgin-245 interaction. in Blood 2009
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Human Monoclonal CD99 Primary Antibody for FACS, IF - ABIN1112237
Sebire, Gibson, Rampling, Williams, Malone, Ramsay: Immunohistochemical findings in embryonal small round cell tumors with molecular diagnostic confirmation. in Applied immunohistochemistry & molecular morphology : AIMM / official publication of the Society for Applied Immunohistochemistry 2005
Human Monoclonal CD99 Primary Antibody for ELISA, WB - ABIN561821
Mynatt, Feldman, Thompson: Orbital infantile myofibroma: a case report and clinicopathologic review of 24 cases from the literature. in Head and neck pathology 2011
endothelial CD99 promotes leukocyte attachment to endothelium in inflamed vessels by a heterophilic ligand. In addition, CD99 binds to PILRs on neutrophils, an interaction that leads to increased shear resistance of the neutrophil attachment to ICAM-1 (show ICAM1 Antibodies).
Endothelial CD99 signals through soluble adenylyl cyclase (show ADCY10 Antibodies) and PKA to regulate leukocyte transendothelial migration.
role in membrane trafficking of CD99L2 (show CD99L2 Antibodies) and in controlling transendothelial migration of leukocytes
CD99 plays a crucial role in the attenuation of graft-versus-host disease by regulating the expansion of myeloid-derived suppressor cells.
CD99L2 (show CD99L2 Antibodies) and CD99 are involved in transendothelial migration of neutrophils in vitro and in the recruitment of neutrophils into inflamed peritoneum
These findings indicate that sialylated O-linked sugar structures on CD99 play an important role in the recognition of PILR.
Vaccination against CD99 inhibits atherogenesis in low-density lipoprotein receptor (show LDLR Antibodies)-deficient mice.
Mouse CD99 is expressed on mouse leukocytes as well as enriched at the endothelial cell borders.
Besides confirming the importance of CD99, findings indicate that polymorphic variations in this gene may affect either development or progression of EWS (show EWSR1 Antibodies).
CD99 is a marker of acute myeloid leukemia (show BCL11A Antibodies) and myelodysplastic syndrome stem cells
CD99 expression is increased in patients with active Inflammatory bowel disease, and positively correlated with disease activity.
CD99 counteracts EWS (show EWSR1 Antibodies)-FLI1 (show FLI1 Antibodies) in controlling NF-kappaB (show NFKB1 Antibodies) signaling through the miR (show MLXIP Antibodies)-34a, which is increased and secreted into exosomes released by CD99-silenced Ewing sarcoma cells.
these observations suggest that CD99 is involved in the regulation of CD1a (show CD1A Antibodies) transcription and expression by increasing ATF-2 (show ATF2 Antibodies).
CD99 was also paranuclear positive in 4 of 11 (36%) small cell lung carcinomas
Data show that CD99 antigen expression increased during in vitro differentiation of germinal center B cells and was highest in plasma cells (PCs).
Our results suggest that the CD34 (show CD34 Antibodies)/CD25 (show IL2RA Antibodies)/CD123 (show IL3RA Antibodies)/CD99(+) LAIP is strictly associated with FLT3 (show FLT3 Antibodies)-ITD-positive cells.
These results suggest that SEPTIN2-mediated cytoskeletal rearrangement and STATHMIN (show STMN1 Antibodies)-mediated differentiation may contribute to changes in cell morphology and differentiation of H/RS cells with CD99 upregulation in Hodgkin lymphoma.
The results highlight an important role of CD99 in the differentiation and activity of human osteoblasts in physiological and pathological conditions.
The protein encoded by this gene is a cell surface glycoprotein involved in leukocyte migration, T-cell adhesion, ganglioside GM1 and transmembrane protein transport, and T-cell death by a caspase-independent pathway. In addition, the encoded protein may have the ability to rearrange the actin cytoskeleton and may also act as an oncosuppressor in osteosarcoma. Cyclophilin A binds to CD99 and may act as a signaling regulator of CD99. This gene is found in the pseudoautosomal region of chromosomes X and Y and escapes X-chromosome inactivation. Three transcript variants encoding different isoforms have been found for this gene.
paired immunoglobin-like type 2 receptor-ligand
, CD99 antigen
, E2 antigen
, MIC2 (monoclonal antibody 12E7)
, T-cell surface glycoprotein E2
, antigen identified by monoclonal 12E7, Y homolog
, antigen identified by monoclonal antibodies 12E7, F21 and O13
, surface antigen MIC2