anti-CD99 (CD99) Antibodies

The protein encoded by CD99 is a cell surface glycoprotein involved in leukocyte migration, T-cell adhesion, ganglioside GM1 and transmembrane protein transport, and T-cell death by a caspase-independent pathway. Additionally we are shipping CD99 Proteins (27) and CD99 Kits (23) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
CD99 673094 Q8VCN6
CD99 4267 P14209
CD99 652929  
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Top anti-CD99 Antibodies at antibodies-online.com

Showing 10 out of 378 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Delivery Price Details
Mouse Rabbit Un-conjugated IF (p), IHC (p), WB Mouse lung lysates probed with Anti-CD99 Polyclonal Antibody, Unconjugated  at 1:5000 90min in 37˚C. 100 μL 3 to 7 Days
$329.45
Details
Human Mouse Un-conjugated IHC, IHC (p), WB 100 μL 11 to 14 Days
$522.50
Details
Human Rabbit Un-conjugated IF, ELISA Immunofluorescence analysis of COS7 cells, using CD99 Antibody. The picture on the right is treated with the synthesized peptide. 100 μg 2 to 3 Days
$302.50
Details
Human Mouse PE FACS, IHC (p), IP, WB Surface staining of human peripheral blood with anti-CD99R (MEM-131) PE. 100 Tests 5 to 7 Days
$497.45
Details
Human Mouse APC FACS, IF, IHC (f) 250 μL 3 to 4 Days
$441.85
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Human Mouse PerCP FACS, IF, IHC (f) 250 μL 3 to 4 Days
$441.85
Details
Human Mouse PE FACS, IF, IHC (f) 250 μL 3 to 4 Days
$441.85
Details
Human Mouse Un-conjugated FACS, IF, IHC (f) 50 μL 3 to 4 Days
$455.38
Details
Human Mouse Un-conjugated FACS, IHC, IHC (p), IP, WB Human Thymus (formalin-fixed, paraffin-embedded) stained with CD99 antibody ABIN239808 at 10 ug/ml followed by biotinylated anti-mouse IgG secondary antibody ABIN481714, alkaline phosphatase-streptavidin and chromogen. Anti-CD99 antibody IHC of human thymus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml. 0.05 mg 11 to 14 Days
$484.00
Details
Human Rabbit Un-conjugated ELISA, IHC, WB Western blot analysis of U937 cell lysate, using CD99 Antibody. The lane on the left is treated with the antigen-specific peptide. ABIN6277025 at 1/100 staining Human urothelial cancer tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22¡ãC. An HRP conjugated goat anti-rabbit antibody was used as the secondary 100 μL 11 to 12 Days
$390.77
Details

Top referenced anti-CD99 Antibodies

  1. Human Monoclonal CD99 Primary Antibody for FACS, MCA - ABIN2749207 : Waclavicek, Majdic, Stulnig, Berger, Sunder-Plassmann, Zlabinger, Baumruker, Stöckl, Ebner, Knapp, Pickl: CD99 engagement on human peripheral blood T cells results in TCR/CD3-dependent cellular activation and allows for Th1-restricted cytokine production. in Journal of immunology (Baltimore, Md. : 1950) 1998 (PubMed)
    Show all 3 Pubmed References

  2. Human Monoclonal CD99 Primary Antibody for FACS, MCA - ABIN1027669 : Kueng, Leb, Haiderer, Raposo, Thery, Derdak, Schmetterer, Neunkirchner, Sillaber, Seed, Pickl: General strategy for decoration of enveloped viruses with functionally active lipid-modified cytokines. in Journal of virology 2007 (PubMed)
    Show all 3 Pubmed References

  3. Mouse (Murine) Polyclonal CD99 Primary Antibody for CyTOF, FACS - ABIN4899868 : Sun, Senger, Baginski, Mazloom, Chinn, Pantua, Hamidzadeh, Ramani, Luis, Tom, Sebrell, Quinones, Ma, Mukhyala, Sai, Ding, Haley, Shadnia, Kapadia, Gonzalez, Hass, Zarrin: Evolutionarily conserved paired immunoglobulin-like receptor α (PILRα) domain mediates its interaction with diverse sialylated ligands. in The Journal of biological chemistry 2012 (PubMed)
    Show all 3 Pubmed References

  4. Human Monoclonal CD99 Primary Antibody for FACS - ABIN2689467 : Aussel, Bernard, Breittmayer, Pelassy, Zoccola, Bernard: Monoclonal antibodies directed against the E2 protein (MIC2 gene product) induce exposure of phosphatidylserine at the thymocyte cell surface. in Biochemistry 1993 (PubMed)
    Show all 3 Pubmed References

  5. Human Monoclonal CD99 Primary Antibody for FACS - ABIN536584 : Bernard, Breittmayer, de Matteis, Trampont, Hofman, Senik, Bernard: Apoptosis of immature thymocytes mediated by E2/CD99. in Journal of immunology (Baltimore, Md. : 1950) 1997 (PubMed)
    Show all 3 Pubmed References

  6. Human Monoclonal CD99 Primary Antibody for FACS, IHC (p) - ABIN457371 : Bernard, Raimondi, Alberti, Pourtein, Widjenes, Ticchioni, Bernard: CD99 (E2) up-regulates alpha4beta1-dependent T cell adhesion to inflamed vascular endothelium under flow conditions. in European journal of immunology 2000 (PubMed)
    Show all 6 Pubmed References

  7. Human Monoclonal CD99 Primary Antibody for FACS, MCA - ABIN1027667 : Brémond, Meynet, Mahiddine, Coito, Tichet, Scotlandi, Breittmayer, Gounon, Gleeson, Bernard, Bernard: Regulation of HLA class I surface expression requires CD99 and p230/golgin-245 interaction. in Blood 2009 (PubMed)
    Show all 2 Pubmed References

  8. Human Monoclonal CD99 Primary Antibody for FACS, IHC (p) - ABIN94260 : Bernard, Zoccola, Deckert, Breittmayer, Aussel, Bernard: The E2 molecule (CD99) specifically triggers homotypic aggregation of CD4+ CD8+ thymocytes. in Journal of immunology (Baltimore, Md. : 1950) 1995 (PubMed)
    Show all 6 Pubmed References

  9. Human Polyclonal CD99 Primary Antibody for CyTOF, FACS - ABIN4899714 : Bedau, Peters, Prox, Arnold, Schmidt, Finkernagel, Köllmann, Wichert, Otte, Ohler, Stirnberg, Lucius, Koudelka, Tholey, Biasin, Pietrzik, Kwapiszewska, Becker-Pauly: Ectodomain shedding of CD99 within highly conserved regions is mediated by the metalloprotease meprin β and promotes transendothelial cell migration. in FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2017 (PubMed)
    Show all 2 Pubmed References

More Antibodies against CD99 Interaction Partners

Mouse (Murine) CD99 interaction partners

  1. endothelial CD99 promotes leukocyte attachment to endothelium in inflamed vessels by a heterophilic ligand. In addition, CD99 binds to PILRs on neutrophils, an interaction that leads to increased shear resistance of the neutrophil attachment to ICAM-1.

  2. Endothelial CD99 signals through soluble adenylyl cyclase and PKA to regulate leukocyte transendothelial migration.

  3. role in membrane trafficking of CD99L2 and in controlling transendothelial migration of leukocytes

  4. CD99 plays a crucial role in the attenuation of graft-versus-host disease by regulating the expansion of myeloid-derived suppressor cells.

  5. CD99L2 and CD99 are involved in transendothelial migration of neutrophils in vitro and in the recruitment of neutrophils into inflamed peritoneum

  6. These findings indicate that sialylated O-linked sugar structures on CD99 play an important role in the recognition of PILR.

  7. Vaccination against CD99 inhibits atherogenesis in low-density lipoprotein receptor-deficient mice.

  8. Mouse CD99 is expressed on mouse leukocytes as well as enriched at the endothelial cell borders.

Human CD99 interaction partners

  1. Authors demonstrated that ligation of CD99 on monocytes by anti-CD99 mAb MT99/3 could mediate T cell hypo-responsiveness. These findings provide the first evidence of the role of CD99 on monocytes that contributes to T cell activation.

  2. Most cases stained positive for CD99 and negative for lymphocytic markers. Markers of epithelial differentiation displayed variable results. In all cases tested, characteristic translocations were displayed supporting the diagnosis.

  3. findings demonstrate that high expression levels of CD99 are mainly found in high-risk BCP-ALL, e.g. BCR-ABL1 and CRLF2(Re/Hi) , and that high CD99 mRNA levels are strongly associated with a high frequency of relapse, high proportion of positive for minimal residual disease at day 29 and poor overall survival in paediatric cohorts

  4. Study showed that isoform 1, of CD99, is exclusively present in human astrocytomas and cell line and regulates functions, such as cytoskeleton remodeling, cell migration, invasion, and adhesion. The present transcriptome data of CD99 silenced GBM cells, suggest that CD99 modulates FAK1/c-Src signaling pathways, related to actin cytoskeleton dynamics.

  5. In summary, we established that tumor suppressor CD99 is markedly downregulated in multiple myeloma.

  6. The present findings identify the genetic basis of the erythroid-specific Xg(a)/CD99 blood group phenotypes and reveal the molecular background of their formation.

  7. Besides confirming the importance of CD99, findings indicate that polymorphic variations in this gene may affect either development or progression of EWS.

  8. CD99 is a marker of acute myeloid leukemia and myelodysplastic syndrome stem cells

  9. CD99 expression is increased in patients with active Inflammatory bowel disease, and positively correlated with disease activity.

  10. CD99 counteracts EWS-FLI1 in controlling NF-kappaB signaling through the miR-34a, which is increased and secreted into exosomes released by CD99-silenced Ewing sarcoma cells.

  11. these observations suggest that CD99 is involved in the regulation of CD1a transcription and expression by increasing ATF-2.

  12. CD99 was also paranuclear positive in 4 of 11 (36%) small cell lung carcinomas

  13. High expression of EMMPRIN plays a crucial role in breast cancer cell proliferation, matrigel invasion and tumor formation.

  14. Data show that CD99 antigen expression increased during in vitro differentiation of germinal center B cells and was highest in plasma cells (PCs).

  15. Our results suggest that the CD34/CD25/CD123/CD99(+) LAIP is strictly associated with FLT3-ITD-positive cells.

  16. These results suggest that SEPTIN2-mediated cytoskeletal rearrangement and STATHMIN-mediated differentiation may contribute to changes in cell morphology and differentiation of H/RS cells with CD99 upregulation in Hodgkin lymphoma.

  17. The results highlight an important role of CD99 in the differentiation and activity of human osteoblasts in physiological and pathological conditions.

  18. CD99 can suppress CD98-mediated assembly of pro-tumorigenic signaling complexes through its ability to dephosphorylate focal adhesion kinase.

  19. CD99 expression in astrocytomas of different malignant grades might contribute to the infiltrative ability and support the importance of CD99 as a potential target to reduce infiltrative astrocytoma capacity in migration and invasion.

  20. The dAbd C7 induced rapid and massive EWS cell death through Mdm2 degradation and p53 reactivation. Mdm2 overexpression as well as silencing of p53 in p53wt EWS cells decreased CD99-induced EWS cell death

CD99 Antigen Profile

Protein Summary

The protein encoded by this gene is a cell surface glycoprotein involved in leukocyte migration, T-cell adhesion, ganglioside GM1 and transmembrane protein transport, and T-cell death by a caspase-independent pathway. In addition, the encoded protein may have the ability to rearrange the actin cytoskeleton and may also act as an oncosuppressor in osteosarcoma. Cyclophilin A binds to CD99 and may act as a signaling regulator of CD99. This gene is found in the pseudoautosomal region of chromosomes X and Y and escapes X-chromosome inactivation. Three transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with anti-CD99 (CD99) Antibodies

  • CD99 antigen (Cd99) antibody
  • CD99 molecule (Xg blood group) (CD99) antibody
  • CD99 molecule (Xg blood group) (Cd99) antibody
  • CD99 molecule (CD99) antibody
  • 1110061M03Rik antibody
  • 2410026K10Rik antibody
  • D4 antibody
  • HBA71 antibody
  • MIC2 antibody
  • MIC2X antibody
  • MIC2Y antibody
  • MSK5X antibody
  • pilr-1 antibody
  • Pilr-l antibody

Protein level used designations for anti-CD99 (CD99) Antibodies

paired immunoglobin-like type 2 receptor-ligand , CD99 antigen , E2 antigen , MIC2 (monoclonal antibody 12E7) , T-cell surface glycoprotein E2 , antigen identified by monoclonal 12E7, Y homolog , antigen identified by monoclonal antibodies 12E7, F21 and O13 , surface antigen MIC2

GENE ID SPECIES
673094 Mus musculus
4267 Homo sapiens
652929 Rattus norvegicus
418662 Gallus gallus
101115513 Ovis aries
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