anti-CDC14 Cell Division Cycle 14 Homolog A (S. Cerevisiae) (CDC14A) Antibodies

The protein encoded by CDC14A is a member of the dual specificity protein tyrosine phosphatase family. Additionally we are shipping CDC14A Proteins (4) and and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
CDC14A 8556 Q9UNH5
CDC14A 229776 Q6GQT0
CDC14A 310806  
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Top anti-CDC14A Antibodies at antibodies-online.com

Showing 10 out of 81 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Delivery Price Details
Cow Rabbit Un-conjugated WB 100 μL 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated ELISA, ICC, IF, WB Western blot analysis of extracts from HeLa cells, using CC14A antibody. ABIN6275796 staining HeLa cells by IF/ICC. The sample were fixed with PFA and permeabilized in 0.1% Triton X-100,then blocked in 10% serum for 45 minutes at 25¡ãC. The primary antibody was diluted at 1/200 and incubated with the sample for 1 hour at 37¡ãC. An Alexa Fluor 594 conjugated goat anti-rabbit IgG (H+L) antibody(Cat.# S0006), diluted at 1/600, was used as secondary antibod 100 μL 11 to 12 Days
$390.77
Details
Human Mouse Un-conjugated IF, ELISA, WB Detection limit for recombinant GST tagged CDC14A is approximately 3ng/ml as a capture antibody. Western Blot analysis of CDC14A expression in transfected 293T cell line by CDC14A monoclonal antibody (M01), clone 2C12.Lane 1: CDC14A transfected lysate(66.6 KDa).Lane 2: Non-transfected lysate. 100 μg 11 to 12 Days
$440.00
Details
Human Rabbit Un-conjugated WB Western blot analysis in A549 cell line lysates (35ug/lane). 400 μL 2 to 3 Days
$515.63
Details
Human Rabbit Un-conjugated FACS, IHC (p), WB Western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstratesdetected the cdc14 protein (arrow). Cdc14 Antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human stomach tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. 400 μL 2 to 3 Days
$515.63
Details
Human Rabbit Un-conjugated FACS, IHC, WB Western blot analysis of extracts of HepG2 cells, using CDC14A antibody (ABIN5972356). 100 μL 11 to 16 Days
$426.40
Details
Cow Rabbit Un-conjugated WB   100 μL 11 to 14 Days
$551.83
Details
Human Mouse Un-conjugated WB Western Blot analysis of CDC14A expression in transfected 293T cell line by CDC14A MaxPab polyclonal antibody.Lane 1: CDC14A transfected lysate(66.60 KDa).Lane 2: Non-transfected lysate. 50 μg 11 to 12 Days
$440.00
Details
Human Rabbit Un-conjugated ELISA, WB   200 μL 11 to 16 Days
$658.43
Details
Human Rabbit Un-conjugated IF, WB   100 μg 11 to 14 Days
$947.83
Details

Top referenced anti-CDC14A Antibodies

  1. Human Polyclonal CDC14A Primary Antibody for ICC, IF - ABIN4296773 : Imtiaz, Belyantseva, Beirl, Fenollar-Ferrer, Bashir, Bukhari, Bouzid, Shaukat, Azaiez, Booth, Kahrizi, Najmabadi, Maqsood, Wilson, Fitzgerald, Tlili, Olszewski, Lund, Chaudhry, Rehman, Starost et al.: CDC14A phosphatase is essential for hearing and male fertility in mouse and human. ... in Human molecular genetics 1970 (PubMed)

More Antibodies against CDC14A Interaction Partners

Human CDC14 Cell Division Cycle 14 Homolog A (S. Cerevisiae) (CDC14A) interaction partners

  1. Point to differences in Cdk1-mediated mechanisms of regulation between human and yeast Cdc14 orthologues.

  2. we show that drebrin and hCDC14A regulate the recruitment of the actin organizer Arp2 to centrosomes. In addition, during ciliogenesis hCDC14A also regulates endocytosis and targeting of myosin Va vesicles to the basal body in a drebrin-independent manner, indicating that it impacts primary cilia formation in a multilayered manner.

  3. CDC14A activity is necessary for hearing and male fertility.

  4. Reduction in the levels of hCDC14A and eplin mRNA is frequently associated with colorectal carcinoma and is correlated with poor prognosis. Authors therefore propose that eplin dephosphorylation by hCDC14A reduces actin dynamics to restrict tumor malignancy.

  5. Mutations in CDC14A gene are associated with Autosomal-Recessive Severe to Profound Deafness.

  6. Overexpressed miR-301a may increase CDC14A expression and promote cell proliferation and migration in osteosarcomacells. Therefore, miR- 301a may be useful for osteosarcoma diagnosis and therapy.

  7. hCDC14A is down-regulated in many tumor tissues and reduced hCDC14A expression is correlated with poorer survival of patients with cancer

  8. These findings indicated that ZIPK may also be involved in the regulation of the cell cycle in human cells, by interacting with HsCdc14A.

  9. hCdc14A might be involved in cell cycle regulation in cultured human brain vascular endothelial cells during high glucose-, free fatty acids-, and hypoxia-induced injury.

  10. These data support the hypothesis that Cdc14A counteracts Cdk1-cyclin B1 activity through Wee1 dephosphorylation.

  11. CDC (cell division cycle) 14A/B phosphatases associate with KIBRA, and CDK1-non-phosphorylatable KIBRA has greatly reduced interaction with CDC14B.

  12. Cdc14 phosphatase plays a role in cell cycle control in higher eukaryotes.

  13. Cdc14A phosphatase prevents premature activation of Cdk1 regulating Cdc25A and Cdc25B at the entry into mitosis.

  14. human HCT116, and human telomerase reverse transcription-immortalized retinal pigment epithelial cells deleted for Cdc14A are DNA damage checkpoint proficient and arrest efficiently in G2 in response to irradiation.

  15. human Cdc14A phosphatase disrupts centrosome separation

  16. Data suggest that hCdc14A phosphatase plays a role in the regulation of the centrosome cycle, mitosis, and cytokinesis, thereby influencing chromosome partitioning and genomic stability in human cells.

  17. hCdc14A and hCdc14B have functional homology to S. pombe Cdc25 and flp1

  18. analysis of iron-responsive elements in the 3'UTR of CDC14a protein

  19. hCdc14A is differentially expressed in human cancer cells and can interact with both p53 and the Cdk1/cyclin B complex; it may play a role in carcinogenesis

  20. Cdc14A may be involved in the cell cycle regulation of Cdc25A stability.

Xenopus laevis CDC14 Cell Division Cycle 14 Homolog A (S. Cerevisiae) (CDC14A) interaction partners

  1. results provide evidence that XCdc14alpha/beta are required for normal cellular division and are regulated by at least two mechanisms, subcellular localization and possibly phosphorylation

  2. We demonstrate that XCdc14A upregulation prevents targeting of exocyst and SNARE complexes to the midbody, both essential for abscission to occur.

Mouse (Murine) CDC14 Cell Division Cycle 14 Homolog A (S. Cerevisiae) (CDC14A) interaction partners

  1. CDC14A activity is necessary for hearing and male fertility.

  2. Cdc14B knockout (Cdc14B(-/-)) mouse embryonic fibroblasts showed defects in repairing ionizing radiation-induced DNA double-strand breaks, which occurred only at late passages when Cdc14A levels were low.

  3. CDC14A regulates oocyte maturation and functions to promote the meiosis I-to-meiosis II transition as its homolog does in budding yeast.

Zebrafish CDC14 Cell Division Cycle 14 Homolog A (S. Cerevisiae) (CDC14A) interaction partners

  1. these studies demonstrate for the first time that Cdc14A and Cdc14B have overlapping functions in the ciliogenesis process during zebrafish development.

CDC14A Antigen Profile

Protein Summary

The protein encoded by this gene is a member of the dual specificity protein tyrosine phosphatase family. It is highly similar to Saccharomyces cerevisiae Cdc14, a protein tyrosine phosphatase involved in the exit of cell mitosis and initiation of DNA replication, suggesting a role in cell cycle control. This protein has been shown to interact with, and dephosphorylate tumor suppressor protein p53, and is thought to regulate the function of p53. Alternative splicing of this gene results in several transcript variants encoding distinct isoforms.

Gene names and symbols associated with CDC14A

  • cell division cycle 14A (CDC14A) antibody
  • Dual specificity protein phosphatase CDC14A (TVAG_168700) antibody
  • Dual specificity protein phosphatase CDC14A (TVAG_479730) antibody
  • Dual specificity protein phosphatase CDC14A (TVAG_362610) antibody
  • Dual specificity protein phosphatase CDC14A (TVAG_490830) antibody
  • Dual specificity protein phosphatase CDC14A (GL50803_9270) antibody
  • dual specificity protein phosphatase CDC14A (CMU_014610) antibody
  • cell division cycle 14A L homeolog (cdc14a.L) antibody
  • CDC14 cell division cycle 14A (Cdc14a) antibody
  • cell division cycle 14A (Cdc14a) antibody
  • cell division cycle 14A (cdc14a) antibody
  • cell division cycle 14Aa (cdc14aa) antibody
  • A830059A17Rik antibody
  • Cdc14 antibody
  • CDC14A antibody
  • CDC14a1 antibody
  • CDC14A2 antibody
  • hCDC14 antibody
  • xcdc14a antibody
  • zgc:63654 antibody

Protein level used designations for CDC14A

CDC10 (cell division cycle 10, S. cerevisiae, homolog) , CDC14 cell division cycle 14 homolog A , dual specificity protein phosphatase CDC14A , Dual specificity protein phosphatase CDC14A , cell division cycle 14 homolog A , CDC14 homolog A , CDC14 cell division cycle 14 homolog A (S. cerevisiae) , dual specificity protein phosphatase CDC14A-like , CDC14 cell division cycle 14 homolog A, a , cdc14a1 , cell division cycle 14Aa

GENE ID SPECIES
8556 Homo sapiens
4753421 Trichomonas vaginalis G3
4756602 Trichomonas vaginalis G3
4769839 Trichomonas vaginalis G3
4771944 Trichomonas vaginalis G3
5701321 Giardia lamblia ATCC 50803
6996284 Cryptosporidium muris RN66
403393 Xenopus laevis
229776 Mus musculus
310806 Rattus norvegicus
424466 Gallus gallus
457058 Pan troglodytes
479926 Canis lupus familiaris
614777 Bos taurus
100346294 Oryctolagus cuniculus
100477147 Ailuropoda melanoleuca
100490252 Xenopus (Silurana) tropicalis
100722401 Cavia porcellus
394124 Danio rerio
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