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CDC14A Products

(CDC14 Cell Division Cycle 14 Homolog A (CDC14A))

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The protein encoded by this gene is a member of the dual specificity protein tyrosine phosphatase family. It is highly similar to Saccharomyces cerevisiae Cdc14, a protein tyrosine phosphatase involved in the exit of cell mitosis and initiation of DNA replication, suggesting a role in cell cycle control. This protein has been shown to interact with, and dephosphorylate tumor suppressor protein p53, and is thought to regulate the function of p53. Alternative splicing of this gene results in several transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008].

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Featured CDC14A Categories

CDC14A Antibodies

High quality antibodies with extensive validation data.

CDC14A Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended CDC14A Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, IF
Validations
  • (4)
Cat. No. ABIN563688
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IF
Validations
  • (4)
Cat. No. ABIN563689
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, FACS, IHC (p)
Validations
  • (3)
Cat. No. ABIN652436
Quantity 400 μL
Datasheet Datasheet

Recommended CDC14A ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6213479
Quantity 96 tests
Datasheet Datasheet

Recommended CDC14A Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1348766
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1348765
Quantity 25 μg
Datasheet Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
  • (1)
Cat. No. ABIN3090949
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our CDC14A products

Mailand, Lukas, Kaiser, Jackson, Bartek, Lukas: "Deregulated human Cdc14A phosphatase disrupts centrosome separation and chromosome segregation." in: Nature cell biology, Vol. 4, Issue 4, pp. 317-22, (2002) (PubMed).

Kaiser, Zimmerman, Charbonneau, Jackson: "Disruption of centrosome structure, chromosome segregation, and cytokinesis by misexpression of human Cdc14A phosphatase." in: Molecular biology of the cell, Vol. 13, Issue 7, pp. 2289-300, (2002) (PubMed).

Bembenek, Yu: "Regulation of the anaphase-promoting complex by the dual specificity phosphatase human Cdc14a." in: The Journal of biological chemistry, Vol. 276, Issue 51, pp. 48237-42, (2001) (PubMed).

Imtiaz, Belyantseva, Beirl, Fenollar-Ferrer, Bashir, Bukhari, Bouzid, Shaukat, Azaiez, Booth, Kahrizi, Najmabadi, Maqsood, Wilson, Fitzgerald, Tlili, Olszewski, Lund, Chaudhry, Rehman, Starost et al.: "CDC14A phosphatase is essential for hearing and male fertility in mouse and human. ..." in: Human molecular genetics, Vol. 27, Issue 5, pp. 780-798 (PubMed).

Synonyms and alternative names related to CDC14A

cell division cycle 14A (CDC14A), Dual specificity protein phosphatase CDC14A (TVAG_168700), Dual specificity protein phosphatase CDC14A (TVAG_479730), Dual specificity protein phosphatase CDC14A (TVAG_362610), Dual specificity protein phosphatase CDC14A (TVAG_490830), Dual specificity protein phosphatase CDC14A (GL50803_9270), dual specificity protein phosphatase CDC14A (CMU_014610), cell division cycle 14A L homeolog (cdc14a.L), CDC14 cell division cycle 14A (Cdc14a), cell division cycle 14A (Cdc14a), cell division cycle 14A (cdc14a), cell division cycle 14Aa (cdc14aa), A830059A17Rik, cdc14, Cdc14, CDC14A, CDC14a1, CDC14A2, hCDC14, xcdc14a, zgc:63654

Protein level used designations for CDC14A

  • CDC10 (cell division cycle 10, S. cerevisiae, homolog)
  • CDC14 cell division cycle 14 homolog A
  • dual specificity protein phosphatase CDC14A
  • Dual specificity protein phosphatase CDC14A
  • cell division cycle 14 homolog A
  • CDC14 homolog A
  • CDC14 cell division cycle 14 homolog A (S. cerevisiae)
  • dual specificity protein phosphatase CDC14A-like
  • CDC14 cell division cycle 14 homolog A, a
  • cdc14a1
  • cell division cycle 14Aa
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