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The protein encoded by CDC42BPA is a member of the Serine/Threonine protein kinase family. Additionally we are shipping CDC42BPA Proteins (4) and many more products for this protein.
Showing 10 out of 60 products:
Human Polyclonal CDC42BPA Primary Antibody for IHC (p), IHC - ABIN268564
Zhao, Loyer, Li, Valentine, Kidd, Kraft: Cloning and chromosomal location of a novel member of the myotonic dystrophy family of protein kinases. in The Journal of biological chemistry 1997
Human Polyclonal CDC42BPA Primary Antibody for ICC, WB - ABIN509569
Cmejla, Ptackova, Petrak, Savvulidi, Cerny, Sebesta, Vyoral: Human MRCKalpha is regulated by cellular iron levels and interferes with transferrin iron uptake. in Biochemical and biophysical research communications 2010
Show all 4 Pubmed References
Cdc42BPA and Cdc42 (show CDC42 Antibodies) signaling are important for colon cancer invasion, and Cdc42BPA has potential implications for colon cancer prognosis and treatment.
Silencing of CDC42BPA expression partially reduces miR29a3p inhibitor-induced migration and invasion of SW4807 cells
ICAP-1 (show ITGB1BP1 Antibodies) monoubiquitylation helps in switching from ROCK2 (show ROCK2 Antibodies)-mediated to MRCKalpha-mediated cell contractility.
Data show that the fusion gene cyclin D1 (show CCND1 Antibodies)/myotonic dystrophy kinase-related CDC42-binding protein kinase alpha (CCND1 (show CCND1 Antibodies)/MRCK) mRNA is resistant to CCND1 (show CCND1 Antibodies)-targeted miRNA regulation.
the functional relevance of the LRAP25-MRCK complex in LIMK1 (show LIMK1 Antibodies)-cofilin (show CFL1 Antibodies) signaling and the importance of LRAP (show ERAP2 Antibodies) adaptors as key determinants of MRCK cellular localization and downstream specificities.
MRCK participates in mediating the effects of HMI-1a3 on HeLa cell morphology.
A functional pathway involving PDK1-mediated activation of MRCKA, links EGF signaling to myosin contraction and directional migration.
Data show that chelerythrine blocks cellular activity of MRCK resulted in the specific loss of NM II-associated MLC phosphorylation in the lamella, and the consequential suppression of cell migration.
MRCKalpha takes part in transferrin (show Tf Antibodies) (Tf)-iron uptake, probably via regulation of Tf- TfR (show TFRC Antibodies) endocytosis/endosome trafficking that is dependent on the cellular cytoskeleton.
Class II histone deacetylases are directly recruited by BCL6 (show BCL6 Antibodies) transcriptional repressor
The protein encoded by this gene is a member of the Serine/Threonine protein kinase family. This kinase contains multiple functional domains. Its kinase domain is highly similar to that of the myotonic dystrophy protein kinase (DMPK). This kinase also contains a Rac interactive binding (CRIB) domain, and has been shown to bind CDC42. It may function as a CDC42 downstream effector mediating CDC42 induced peripheral actin formation, and promoting cytoskeletal reorganization. Multiple alternatively spliced transcript variants have been described, and the full-length nature of two of them has been reported.
CDC42 binidng protein kinase beta
, CDC42-binding protein kinase alpha (DMPK-like)
, DMPK-like alpha
, MRCK alpha
, myotonic dystrophy kinase-related CDC42-binding kinase alpha
, myotonic dystrophy kinase-related CDC42-binding protein kinase alpha
, myotonic dystrophy protein kinase-like alpha
, ser-thr protein kinase PK428
, ser-thr protein kinase related to the myotonic dystrophy protein kinase
, serine/threonine-protein kinase MRCK alpha
, CDC42-binding protein kinase alpha
, Ser-Thr protein kinase related to the myotonic dystrophy protein kinase
, mytonic dystrophy kinase-related Cdc42-binding kinase
, myotonic dystrophy kinase-related CDC-42-binding kinase-alpha
, CDC42 binding protein kinase alpha (DMPK-like)
, CDC42 binding protein kinase alpha-like
, serine/threonine-protein kinase MRCK alpha-like