CDC42BPA Products
(CDC42 Binding Protein Kinase alpha (DMPK-Like) (CDC42BPA))
Categories
The protein encoded by this gene is a member of the Serine/Threonine protein kinase family. This kinase contains multiple functional domains. Its kinase domain is highly similar to that of the myotonic dystrophy protein kinase (DMPK). This kinase also contains a Rac interactive binding (CRIB) domain, and has been shown to bind CDC42. It may function as a CDC42 downstream effector mediating CDC42 induced peripheral actin formation, and promoting cytoskeletal reorganization. Multiple alternatively spliced transcript variants have been described, and the full-length nature of two of them has been reported. [provided by RefSeq, Jul 2008].
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Featured CDC42BPA Categories
CDC42BPA Antibodies
High quality antibodies with extensive validation data.
CDC42BPA Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended CDC42BPA Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IF, IHC (p), ICC
Validations
- (3)
Cat. No.
ABIN2855436
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IHC
Validations
- (2)
Cat. No.
ABIN7248404
Quantity
200 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA
Validations
- (2)
Cat. No.
ABIN563644
Quantity
100 μg
Datasheet
Datasheet
Recommended CDC42BPA Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Insect cells (Sf21)
Validations
- (2)
Cat. No.
ABIN5569701
Quantity
5 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1348835
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Insect Cells
Validations
Cat. No.
ABIN5509022
Quantity
10 μg
Datasheet
Datasheet
Latest Publications for our CDC42BPA products
: "Human MRCKalpha is regulated by cellular iron levels and interferes with transferrin iron uptake." in: Biochemical and biophysical research communications, Vol. 395, Issue 2, pp. 163-7, (2010) (PubMed).: "Cdc42 antagonizes inductive action of cAMP on cell shape, via effects of the myotonic dystrophy kinase-related Cdc42-binding kinase (MRCK) on myosin light chain phosphorylation." in: European journal of cell biology, Vol. 81, Issue 4, pp. 231-42, (2002) (PubMed).
: "Intermolecular and intramolecular interactions regulate catalytic activity of myotonic dystrophy kinase-related Cdc42-binding kinase alpha." in: Molecular and cellular biology, Vol. 21, Issue 8, pp. 2767-78, (2001) (PubMed).
: "Characterization of a monoclonal antibody panel shows that the myotonic dystrophy protein kinase, DMPK, is expressed almost exclusively in muscle and heart." in: Human molecular genetics, Vol. 9, Issue 14, pp. 2167-73, (2000) (PubMed).
: "Cloning and chromosomal location of a novel member of the myotonic dystrophy family of protein kinases." in: The Journal of biological chemistry, Vol. 272, Issue 15, pp. 10013-20, (1997) (PubMed).
Synonyms and alternative names related to CDC42BPA
CDC42 binding protein kinase alpha (CDC42BPA), CDC42 binding protein kinase alpha (Cdc42bpa), GDNF family receptor alpha 2 (GFRA2), serine/threonine-protein kinase MRCK alpha (LOC100182779), CDC42 binding protein kinase alpha (DMPK-like) (CDC42BPA), serine/threonine-protein kinase MRCK alpha (LOC100545977), A930014J19Rik, CDC42BPA, DMPK-like, MRCK, Mrck, MRCKA, PK428, Pk428Protein level used designations for CDC42BPA
- CDC42 binidng protein kinase beta
- CDC42-binding protein kinase alpha (DMPK-like)
- DMPK-like alpha
- MRCK alpha
- myotonic dystrophy kinase-related CDC42-binding kinase alpha
- myotonic dystrophy kinase-related CDC42-binding protein kinase alpha
- myotonic dystrophy protein kinase-like alpha
- ser-thr protein kinase PK428
- ser-thr protein kinase related to the myotonic dystrophy protein kinase
- serine/threonine-protein kinase MRCK alpha
- CDC42-binding protein kinase alpha
- Ser-Thr protein kinase related to the myotonic dystrophy protein kinase
- mytonic dystrophy kinase-related Cdc42-binding kinase
- myotonic dystrophy kinase-related CDC-42-binding kinase-alpha
- CDC42 binding protein kinase alpha (DMPK-like)
- CDC42 binding protein kinase alpha-like
- serine/threonine-protein kinase MRCK alpha-like
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