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CASP5 encodes a member of the cysteine-aspartic acid protease (caspase) family. Additionally we are shipping CASP5 Proteins (12) and CASP5 Kits (11) and many more products for this protein.
Showing 10 out of 91 products:
Human Polyclonal CASP5 Primary Antibody for ELISA, ICC - ABIN4287993
Bian, Pelegrino, Pflugfelder, Volpe, Li, de Paiva: Desiccating Stress-Induced MMP Production and Activity Worsens Wound Healing in Alkali-Burned Corneas. in Investigative ophthalmology & visual science 2015
Show all 2 Pubmed References
Human Polyclonal CASP5 Primary Antibody for WB - ABIN2477916
Munday, Vaillancourt, Ali, Casano, Miller, Molineaux, Yamin, Yu, Nicholson: Molecular cloning and pro-apoptotic activity of ICErelII and ICErelIII, members of the ICE/CED-3 family of cysteine proteases. in The Journal of biological chemistry 1995
Show all 4 Pubmed References
Cow (Bovine) Polyclonal CASP5 Primary Antibody for WB - ABIN222884
Bian, Elner, Khanna, Murga-Zamalloa, Patil, Elner: Expression and functional roles of caspase-5 in inflammatory responses of human retinal pigment epithelial cells. in Investigative ophthalmology & visual science 2011
Long non-coding RNA CASP5 promotes the malignant phenotypes of human glioblastoma multiforme.
Study shows that CASP5 was positively correlated with inflammation in rheumatoid arthritis (RA), and provides evidence that certain CASP5 SNPs were associated with an increased risk of RA.
Th17 micro-milieu via IL-17A (show IL17A Antibodies) regulates NLRP1 (show NLRP1 Antibodies)-dependent CASP5 activity in psoriatic skin autoinflammation.
CASP5 gene overexpression significantly promoted angiogenesis ability of HMEC-1 cells, which was probably achieved by inhibiting angpt-1 (show ANGPT1 Antibodies)/Tie2 (show TEK Antibodies) and promoting VEGF (show VEGFA Antibodies)-1 signal pathway.
Caspase-4 (show CASP4 Antibodies) and caspase-5 mediate IL-1alpha and IL-1beta (show IL1B Antibodies) release from human monocytes after lipopolysaccharides stimulation.
The distribution of the other genotypes; rs507879, rs518604 and rs523104 of caspase-5) was not significantly different between patients with psoriasis vulgaris and the healthy controls.
both caspase-4 (show CASP4 Antibodies) and caspase-5 are functionally important for appropriate responses to intracellular Gram-negative bacteria.
Data show that exposure of hepatocytes to direct hypoxia resulted in acid sphingomyelinase (show SMPD1 Antibodies) activation and ceramide elevation associated with activation of caspase 5 and the subsequent cleavage of HuR (show ELAVL1 Antibodies) and apoptotic cell death.
Data suggest a positive association of caspase-3 (show CASP3 Antibodies) and diplotype analysis of caspase-5 to be associated with prostate cancer risk.
Mutual activation between caspase-5 and -1 suggests caspase-5 may work predominantly in concert with caspase-1 (show CASP1 Antibodies) in modulating retinal pigment epithelium inflammatory responses.
This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. Overexpression of the active form of this enzyme induces apoptosis in fibroblasts. Max, a central component of the Myc\\/Max\\/Mad transcription regulation network important for cell growth, differentiation, and apoptosis, is cleaved by this protein\\\\; this process requires Fas-mediated dephosphorylation of Max. The expression of this gene is regulated by interferon-gamma and lipopolysaccharide. Alternatively spliced transcript variants have been identified for this gene.
, TY protease
, caspase 5, apoptosis-related cysteine protease
, protease ICH-3
, protease TY
, caspase 5
, caspase 5, apoptosis-related cysteine peptidase