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The protein encoded by CDC34 is a member of the ubiquitin-conjugating enzyme family. Additionally we are shipping CDC34 Proteins (9) and and many more products for this protein.
Showing 10 out of 57 products:
Human Monoclonal CDC34 Primary Antibody for IP, WB - ABIN152939
Fernandez-Sanchez, Sechet, Margottin-Goguet, Rogge, Bianchi: The human COP9 signalosome protects ubiquitin-conjugating enzyme 3 (UBC3/Cdc34) from beta-transducin repeat-containing protein (betaTrCP)-mediated degradation. in The Journal of biological chemistry 2010
Study shows that Ube2R1/2 forms a salt bridge interaction between a conserved Asp (show ASIP Antibodies) residue on Ube2R1/2 and acceptor ubiquitin residue Arg 54 and that perturbation of this interaction leads to the severe loss of UbeR2 activity. Results also provide new insight into how the Ube2R1/2 acidic loop may participate in catalysis.
ubiquitin binding by the acidic loops of Ube2g1 (show Ube2g1 Antibodies) and Ube2r1 enzymes distinguishes their Lys (show LYZ Antibodies)-48-ubiquitylation activities
We discuss how these results can explain the rapid association of Cdc34 and SCF (show KITLG Antibodies).
Here we have investigated how the acidic loop in human Cdc34 promotes ubiquitination, identifying two key molecular events during which the acidic loop exerts its influence
These data suggest that FBXO15 and Ube2r1 regulate P-gp expression through the ubiquitin-proteasome pathway.
Tristetraprolin (show ZFP36 Antibodies) promotes an increase in expression of mature let-7, which leads to the inhibition of let-7 target gene CDC34 expression and suppresses cell growth.
Data show that anaphase-promoting complex or cyclosome (APC (show APC Antibodies)/C)-mediated multiple monoubiquitylation targeting cyclin B1 (show CCNB1 Antibodies) for degradation.
work provides the first structural details that show how the C-terminus of CDC34 might direct a thiolester-bound Ub to control polyubiquitin (show UBB Antibodies) chain formation
the human Cdc34 carboxyl terminus contains a non-covalent ubiquitin binding activity that contributes to SCF (show KITLG Antibodies)-dependent ubiquitination
COP9 (show COPS8 Antibodies) signalosome protects ubiquitin-conjugating enzyme 3 (UBC3/Cdc34) from beta-transducin repeat-containing protein (betaTrCP (show BTRC Antibodies))-mediated degradation
The protein encoded by this gene is a member of the ubiquitin-conjugating enzyme family. Ubiquitin-conjugating enzyme catalyzes the covalent attachment of ubiquitin to other proteins. This protein is a part of the large multiprotein complex, which is required for ubiquitin-mediated degradation of cell cycle G1 regulators, and for the initiation of DNA replication.
cell division cycle 34 homolog
, ubiquitin carrier protein
, ubiquitin-conjugating enzyme E2 R1
, ubiquitin-conjugating enzyme E2-32 KDA complementing
, ubiquitin-conjugating enzyme E2-CDC34
, ubiquitin-protein ligase R1
, Ubiquitin-conjugating enzyme E2 R1
, ubiquitin-conjugating enzyme Cdc34
, ubiquitin-conjugating enzyme E2-32 kDa complementing
, serine protease
, cell division cycle 34 homolog (S. cerevisiae)
, hypothetical protein
, Ubiquitin-conjugating enzyme E2 R2
, ubiquitin-conjugating enzyme E2-32k