anti-Chitotriosidase (CHIT1) Antibodies

Chitotriosidase is secreted by activated human macrophages and is markedly elevated in plasma of Gaucher disease patients. Additionally we are shipping Chitotriosidase 1 Kits (25) and Chitotriosidase 1 Proteins (17) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
CHIT1 1118 Q13231
CHIT1 289032  
CHIT1 71884 Q9D7Q1
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Top anti-Chitotriosidase 1 Antibodies at antibodies-online.com

Showing 10 out of 72 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Goat Un-conjugated ELISA, WB   100 μg Log in to see 6 to 7 Days
$429.62
Details
Human Mouse Un-conjugated ELISA, WB Figure 1: Western blot analysis using CHIT1 mouse mAb against truncated Trx-CHIT1 recombinant protein (1) and truncated CHIT1 (aa22-466)-hIgGFc transfected CHO-K1 cell lysate (2). Dilution: 1/500 - 1/2000 100 μL Log in to see 10 to 11 Days
$475.29
Details
Human Goat Un-conjugated ELISA, WB 100 μg Log in to see 11 to 14 Days
$610.50
Details
Human Rabbit Un-conjugated WB WB Image Sample (30 ug of whole cell lysate) A: Hela 10% SDS PAGE antibody diluted at 1:1000 100 μL Log in to see 3 to 4 Days
$466.18
Details
Human Mouse Un-conjugated ELISA, WB Western Blot: Chitotriosidase/CHIT1 Antibody (1D9G2) [NBP1-28895] - Western blot analysis using CHIT1 mouse mAb against truncated Trx-CHIT1 recombinant protein (1) and truncated CHIT1 (aa22-466)-hIgGFc transfected CHO-K1 cell lysate (2). 0.1 mL Log in to see 7 to 9 Days
$485.88
Details
Human Goat Un-conjugated ELISA, WB Western Blot: CHIT1 Antibody [NBP1-97774] - (1ug/ml) Analysis of Daudi lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 0.1 mg Log in to see 7 to 9 Days
$485.88
Details
Human Rabbit Un-conjugated ICC, IHC, WB Figure. Western Blot; Sample: Recombinant CHIT1, Human. Figure.DAB staining on IHC-P. Samples: Human Tissue 100 μg Log in to see 15 to 18 Days
$350.00
Details
Mouse Rabbit Un-conjugated ICC, IHC, WB Figure. Western Blot; Sample: Recombinant CHIT1, Mouse. Figure.DAB staining on IHC-P. Samples: Mouse Tissue 100 μg Log in to see 13 to 16 Days
$360.00
Details
Human Rabbit Un-conjugated IHC, WB Western blot analysis of extracts of various cells, using CHIT1 antibody. Immunohistochemistry of paraffin-embedded human normal stomach using CHIT1 antibody at dilution of 1:200 (400x lens). 100 μL Log in to see 16 Days
$334.77
Details
Human Rabbit Un-conjugated IHC, WB Western blot analysis of extracts of various cell lines, using CHIT1 antibody. Immunohistochemistry of paraffin-embedded human normal stomach using CHIT1 antibody. 120 μL Log in to see 12 to 14 Days
$251.90
Details

Top referenced anti-Chitotriosidase 1 Antibodies

  1. Human Monoclonal Chitotriosidase 1 Primary Antibody for ELISA, WB - ABIN969053 : Wajner, Michelin, Burin, Pires, Pereira, Giugliani, Coelho et al.: Comparison between the biochemical properties of plasma chitotriosidase from normal individuals and from patients with Gaucher disease, GM1-gangliosidosis, Krabbe disease and heterozygotes for ... in Clinical biochemistry 2007 (PubMed)
    Show all 2 Pubmed References

  2. Human Monoclonal Chitotriosidase 1 Primary Antibody for ELISA, WB - ABIN449966 : Berger, Hsieh, Bakele, Marcos, Rieber, Kormann, Mays, Hofer, Neth, Vitkov, Krautgartner, von Schweinitz, Kappler, Hector, Weber, Hartl: Neutrophils express distinct RNA receptors in a non-canonical way. in The Journal of biological chemistry 2012 (PubMed)

  3. Human Polyclonal Chitotriosidase 1 Primary Antibody for ELISA, WB - ABIN4297945 : Chien, Lee, Tsai, Chao, Hwu: Reduction in imiglucerase dosage causes immediate rise of chitotriosidase activity in patients with Gaucher disease. in Molecular genetics and metabolism 2010 (PubMed)

More Antibodies against Chitotriosidase 1 Interaction Partners

Human Chitotriosidase (CHIT1) interaction partners

  1. CHIT1 might be considered as a circulating biomarker in polycythemia vera (show IGF2BP3 Antibodies). Additional studies are needed to clarify the role of CHIT1 in promoting disease progression and bone marrow fibrosis in polycythemia vera (show IGF2BP3 Antibodies).

  2. Data suggest that up-regulation of amniotic fluid chitotriosidase may serve as prenatal diagnostic biomarker for lysosomal storage disorders, more specifically for Gaucher and Niemann-Pick A/B diseases; these findings appear to result from gene duplication. This study was conducted in India.

  3. Circulating chitotriosidase is a test which can potentially be used for the monitoring of critical limb ischemia patients without other inflammatory conditions.

  4. All patients with NPC1 (show NPC1 Antibodies) mutations had high ChT (show ChT Antibodies) activity, high CCL18/PARC concentrations and/or Niemann-Pick disease type C suspicion index scores >/=70.

  5. The total allele frequency of the dup24bp in the CHIT1 gene in the Ukrainian population was determined, which amounted to 0.26 (323/1244) that is higher than in the Western European population.

  6. the two variations of CHIT1, rs61745299 and rs35920428, increase expression of the gene and are associated with colorectal cancer in Chinese Han populations

  7. SCD (show SCD Antibodies) children are at risk of developing premature atherogenic changes. Plasma chitotriosidase and CIMT may represent useful predictors of these changes.

  8. chitotriosidase as a possible chronic inflammation marker in children with common variable immunodeficiency and early atherosclerosis

  9. Processivity and the rate constant of dissociation of Human chitotriosidase (HCHT (show ChT Antibodies)) were found to be in-between those, characteristic to processive exo (show PHM Antibodies)-enzymes, like SmChiA and randomly acting non-processive endo-enzymes, like SmChiC. Apart from increasing the affinity for chitin, CBM had no major effect on kinetic properties of HCHT (show ChT Antibodies).

  10. PMA stimulation and preincubation with rhDNase increased CHIT-1 activity in culture supernatants from non-CF and CF donors.Stimulation of isolated leucocytes with PMA and treatment with rhDNase interfered with anti-fungal defence mechanisms.

Mouse (Murine) Chitotriosidase (CHIT1) interaction partners

  1. No significant differences were observed between experimental autoimmune encephalitis and control groups for CHIT-1 expression.

  2. CHIT1 exerts protective effects against atherosclerosis by suppressing inflammatory responses and polarizing macrophages toward an M2 phenotype, and promoting lipid uptake and cholesterol efflux in macrophages.

Horse (Equine) Chitotriosidase (CHIT1) interaction partners

  1. findings showed chitotriosidase, but not AMCase (show CHIA Antibodies), is expressed in trachea, bronchi & peripheral lung tissue; chitotriosidase gene was identified; results indicate the involvement of chitotriosidase in recurrent airway obstruction is uncertain

Chitotriosidase 1 (CHIT1) Antigen Profile

Protein Summary

Chitotriosidase is secreted by activated human macrophages and is markedly elevated in plasma of Gaucher disease patients. The expression of chitotriosidase occurs only at a late stage of differentiation of monocytes to activated macrophages in culture. Human macrophages can synthesize a functional chitotriosidase, a highly conserved enzyme with a strongly regulated expression. This enzyme may play a role in the degradation of chitin-containing pathogens. Several alternatively spliced transcript variants have been described for this gene.

Gene names and symbols associated with anti-Chitotriosidase (CHIT1) Antibodies

  • chitinase 1 (CHIT1) antibody
  • chitinase 1 (chitotriosidase) (chit1) antibody
  • chitinase 1 (Chit1) antibody
  • chitinase 1 (chitotriosidase) (Chit1) antibody
  • 2300002L19Rik antibody
  • CHI3 antibody
  • chio antibody
  • CHIT antibody
  • CHIT1 antibody
  • CHITD antibody

Protein level used designations for anti-Chitotriosidase (CHIT1) Antibodies

chitotriosidase-1 , plasma methylumbelliferyl tetra-N-acetylchitotetraoside hydrolase , chitinase 1 (chitotriosidase) , chitotriosidase , chitinase-1

GENE ID SPECIES
1118 Homo sapiens
703286 Macaca mulatta
448265 Xenopus (Silurana) tropicalis
289032 Rattus norvegicus
71884 Mus musculus
457641 Pan troglodytes
100065255 Equus caballus
100338170 Oryctolagus cuniculus
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