Chitotriosidase is secreted by activated human macrophages and is markedly elevated in plasma of Gaucher disease patients.
Chitotriosidase 1 (CHIT1) Antigen Profile
Chitotriosidase is secreted by activated human macrophages and is markedly elevated in plasma of Gaucher disease patients. The expression of chitotriosidase occurs only at a late stage of differentiation of monocytes to activated macrophages in culture. Human macrophages can synthesize a functional chitotriosidase, a highly conserved enzyme with a strongly regulated expression. This enzyme may play a role in the degradation of chitin-containing pathogens. Several alternatively spliced transcript variants have been described for this gene.
Gene names and symbols associated with anti-Chitotriosidase (CHIT1) Antibodies
chitinase 1 (CHIT1) antibody
chitinase 1 (chitotriosidase) (chit1) antibody
chitinase 1 (Chit1) antibody
chitinase 1 (chitotriosidase) (Chit1) antibody
Protein level used designations for anti-Chitotriosidase (CHIT1) Antibodies