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Chitotriosidase 1 antibody

CHIT1 Reactivity: Human, Mouse IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7260061
  • Target See all Chitotriosidase 1 (CHIT1) Antibodies
    Chitotriosidase 1 (CHIT1) (Chitotriosidase (CHIT1))
    Reactivity
    • 31
    • 4
    • 2
    Human, Mouse
    Host
    • 23
    • 9
    • 1
    Rabbit
    Clonality
    • 26
    • 7
    Polyclonal
    Conjugate
    • 22
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Chitotriosidase 1 antibody is un-conjugated
    Application
    • 21
    • 12
    • 8
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Immunohistochemistry (IHC)
    Characteristics
    Polyclonal Antibody
    Purification
    Affinity purification
    Immunogen
    Recombinant fusion protein of human CHIT1 (NP_003456.1).
    Isotype
    IgG
    Top Product
    Discover our top product CHIT1 Primary Antibody
  • Application Notes
    IHC 1:50-1:200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    Chitotriosidase 1 (CHIT1) (Chitotriosidase (CHIT1))
    Alternative Name
    CHIT1 (CHIT1 Products)
    Synonyms
    CHI3 antibody, CHIT antibody, CHITD antibody, CHIT1 antibody, chio antibody, 2300002L19Rik antibody, chitinase 1 antibody, chitinase 1 (chitotriosidase) antibody, CHIT1 antibody, chit1 antibody, Chit1 antibody
    Background
    Chitotriosidase is secreted by activated human macrophages and is markedly elevated in plasma of Gaucher disease patients. The expression of chitotriosidase occurs only at a late stage of differentiation of monocytes to activated macrophages in culture. Human macrophages can synthesize a functional chitotriosidase, a highly conserved enzyme with a strongly regulated expression. This enzyme may play a role in the degradation of chitin-containing pathogens. Several alternatively spliced transcript variants have been described for this gene.
    Gene ID
    1118
    UniProt
    Q13231
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