anti-Chloride Intracellular Channel 1 (CLIC1) Antibodies

Chloride channels are a diverse group of proteins that regulate fundamental cellular processes including stabilization of cell membrane potential, transepithelial transport, maintenance of intracellular pH, and regulation of cell volume. Additionally we are shipping CLIC1 Proteins (13) and CLIC1 Kits (12) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
CLIC1 1192 O00299
CLIC1 114584 Q9Z1Q5
CLIC1 406864 Q6MG61
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Top anti-CLIC1 Antibodies at antibodies-online.com

Showing 10 out of 113 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-CLIC1 Antibody Titration:  0.2-1 ug/ml  ELISA Titer:  1:312500  Positive Control:  HepG2 cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Cow Rabbit Un-conjugated IHC, WB WB Suggested Anti-CLIC1 Antibody Titration:  1.25ug/ml  ELISA Titer:  1:312500  Positive Control:  Jurkat cell lysate Sample Type: Purified Recombinant CLIC-1 Protein Primary Dilution: 1:1000Submitted By: Harpreet Singh, University of California Los Angeles 100 μL Log in to see 2 to 3 Days
$249.00
Details
Human Goat Un-conjugated ELISA, WB   100 μg Log in to see 6 to 7 Days
$429.84
Details
Human Rabbit Un-conjugated ICC, IHC, WB Figure. Western Blot; Sample: Lane1: Human Liver Tissue; Lane2: Human Lung Tissue; Lane3: Human HL-60 Cells; Lane4: Human Hela Cells. 100 μg Log in to see 13 to 16 Days
$350.00
Details
Bat Rabbit Un-conjugated IHC, IHC (p), WB 100 μg Log in to see 11 to 14 Days
$493.17
Details
Bat Rabbit Un-conjugated WB 100 μg Log in to see 11 to 14 Days
$493.17
Details
Human Mouse Un-conjugated IF, IHC (p), ELISA, WB Immunoperoxidase of monoclonal antibody to CLIC1 on formalin-fixed paraffin-embedded human colon tissue. [antibody concentration 3 ug/ml] CLIC1 monoclonal antibody (M01), clone 2D4 Western Blot analysis of CLIC1 expression in HL-60 . 100 μg Log in to see 11 to 12 Days
$348.04
Details
Human Rabbit Un-conjugated IHC (p), WB Western blot analysis of anti-CLIC1 Antibody (ABIN391851) in A375 cell line lysates (35 µg/lane). CLIC1(arrow) was detected using the purified polyclonal antibody (1:60dilution). Formalin-fixed and paraffin-embedded human lung carcinoma tissue reacted with CLIC1 antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Log in to see 10 to 11 Days
$385.00
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB Formalin-fixed and paraffin-embedded human lung carcinoma tissue reacted with CLIC1 antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. Western blot analysis of anti-CLIC1 Antibody in A375 cell line lysates (35ug/lane). CLIC1(arrow) was detected using the purified Pab (1:60dilution). 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Bat Goat Un-conjugated ELISA, IHC, IHC (p), WB Anti-CLIC1 / NCC27 antibody IHC staining of human colon. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml. 50 μg Log in to see 11 to 14 Days
$639.83
Details

Top referenced anti-CLIC1 Antibodies

  1. Human Polyclonal CLIC1 Primary Antibody for WB - ABIN1881210 : Valenzuela, Martin, Por, Robbins, Warton, Bootcov, Schofield, Campbell, Breit: Molecular cloning and expression of a chloride ion channel of cell nuclei. in The Journal of biological chemistry 1997 (PubMed)
    Show all 3 Pubmed References

  2. Human Monoclonal CLIC1 Primary Antibody for IF, IHC (p) - ABIN560404 : Megger, Bracht, Kohl, Ahrens, Naboulsi, Weber, Hoffmann, Stephan, Kuhlmann, Eisenacher, Schlaak, Baba, Meyer, Sitek: Proteomic differences between hepatocellular carcinoma and nontumorous liver tissue investigated by a combined gel-based and label-free quantitative proteomics study. in Molecular & cellular proteomics : MCP 2013 (PubMed)
    Show all 2 Pubmed References

  3. Cow (Bovine) Polyclonal CLIC1 Primary Antibody for IHC, WB - ABIN2776130 : Novarino, Fabrizi, Tonini, Denti, Malchiodi-Albedi, Lauro, Sacchetti, Paradisi, Ferroni, Curmi, Breit, Mazzanti: Involvement of the intracellular ion channel CLIC1 in microglia-mediated beta-amyloid-induced neurotoxicity. in The Journal of neuroscience : the official journal of the Society for Neuroscience 2004 (PubMed)
    Show all 2 Pubmed References

  4. Human Monoclonal CLIC1 Primary Antibody for IHC (p), ELISA - ABIN560405 : Chaze, Meunier, Chambon, Jurie, Picard: Proteome dynamics during contractile and metabolic differentiation of bovine foetal muscle. in Animal : an international journal of animal bioscience 2012 (PubMed)

More Antibodies against CLIC1 Interaction Partners

Human Chloride Intracellular Channel 1 (CLIC1) interaction partners

  1. After CLIC1 knockdown, the expression levels of ITGalpha3, ITGalphav, ITGbeta1 and Bcl-2 mRNA and protein were decreased significantly in gastric cancer cells, as well as AKT-phosphorylation, ERK-phosphorylation and p38-phosphorylation, were reduced in vivo.

  2. The current study provides the first statistically convincing evidence that downregulation of miR-372 may occur in gallbladder cancer tissues, which may be associated with aggressive and progressive tumor behavior by affecting CLIC1 expression.

  3. The CLIC1-mediated drug resistance is achieved through positive regulation of MRP1 in choriocarcinoma.CLIC1 is highly expressed in chemoresistant choriocarcinoma.

  4. Proteomic analysis indicates that CLIC1 promotes tumorgenesis in epithelial ovarian cancer.

  5. CLIC1 is a possible tumor marker for ovarian cancer. Dendritic cells pulsed with MtHsp70-CLIC1 can enhance antitumor immunity against ovarian cancer, providing a novel immune therapeutic strategy.

  6. Either dysfunction or downregulation of CLIC1 can partially decrease the antineoplastic effects of metformin.

  7. The expression of CLIC1 might be closely related to the carcinogenesis, clinical biological behaviors, and prognosis of pancreatic ductal adenocarcinomas.

  8. Extracellular vesicle-mediated transfer of CLIC1 protein is a novel mechanism for the regulation of glioblastoma growth.

  9. Results indicate that CLIC1 is an important contributor to tumor invasion, metastasis, and angiogenesis.

  10. CLIC1 acts as a putative oncogene in pancreatic cancer.

  11. Data show that glutamate 85 and glutamate 228 are pH-sensor residues of chloride intracellular channel protein CLIC1 and contribute to the pH-response stability in different ways.

  12. CLIC1 and CLIC4 are overexpressed in specific tumor types or their corresponding stroma and change localization and function from hydrophilic cytosolic to integral transmembrane proteins. (Review)

  13. CLIC1 may be a potential sensitive and specific molecular biomarker for early diagnose for serous epithelial ovarian cancers metastasis.

  14. It participates in migration and invasion of hepatocellular carcinoma by targeting maspin.

  15. The expression of CLIC1 is closely related to the progression of gall bladder cancer and may be used as an effective marker for predicting the prognosis of this disease.

  16. Data indicate the chloride channel protein CLIC1 as the most penetrant receptor.

  17. Results indicate that CLIC1 could regulate prostate cancer cell proliferation and migration by regulating the(MAPK)/ERK pathway.

  18. CLIC1 protein is involved in the metastasis of colon cancer LOVO cells via regulating the ROS/ERK pathway in the hypoxia-reoxygenation process

  19. Mutation of the two charged amino acids (K37 and R29) in the putative transmembrane region of CLIC1 alters the biophysical properties of the ion channel in both artificial bilayers and cells.

  20. our results are consistent with a model of CLIC function in which covalent binding of glutathione does not occur spontaneously but requires interaction with another protein to stabilise the GSH binding site and/or transfer of the ligand

CLIC1 Antigen Profile

Protein Summary

Chloride channels are a diverse group of proteins that regulate fundamental cellular processes including stabilization of cell membrane potential, transepithelial transport, maintenance of intracellular pH, and regulation of cell volume. Chloride intracellular channel 1 is a member of the p64 family\; the protein localizes principally to the cell nucleus and exhibits both nuclear and plasma membrane chloride ion channel activity.

Gene names and symbols associated with CLIC1

  • chloride intracellular channel 1 (clic1) antibody
  • chloride intracellular channel 1 (CLIC1) antibody
  • chloride intracellular channel 1 (Clic1) antibody
  • chloride intracellular channel 1 S homeolog (clic1.S) antibody
  • Clcp antibody
  • CLIC1 antibody
  • G6 antibody
  • MGC75951 antibody
  • MGC132377 antibody
  • NCC27 antibody
  • wu:fc30e04 antibody
  • xclic1 antibody
  • zgc:77044 antibody

Protein level used designations for CLIC1

chloride intracellular channel 1 , RNCC protein , chloride channel ABP , chloride intracellular channel protein 1 , hRNCC , nuclear chloride ion channel 27 , nuclear chloride ion channel protein , p64CLCP , regulatory nuclear chloride ion channel protein , NCC27

GENE ID SPECIES
394484 Xenopus (Silurana) tropicalis
462564 Pan troglodytes
715446 Macaca mulatta
1192 Homo sapiens
515646 Bos taurus
100008817 Oryctolagus cuniculus
114584 Mus musculus
406864 Rattus norvegicus
324481 Danio rerio
398656 Xenopus laevis
474847 Canis lupus familiaris
594847 Sus scrofa
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