anti-Chromobox Homolog 7 (CBX7) Antibodies

human homolog interacts with Ring1 and localizes to nuclear Polycomb bodies [RGD, Feb 2006].. Additionally we are shipping CBX7 Proteins (6) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
CBX7 52609 Q8VDS3
CBX7 362962 P60889
CBX7 23492 O95931
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Top anti-CBX7 Antibodies at antibodies-online.com

Showing 10 out of 41 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Delivery Price Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-CBX7 Antibody Titration:  0.2-1 ug/ml  ELISA Titer:  1:62500  Positive Control:  HepG2 cell lysate Host:  Rabbit  Target Name:  CBX7  Sample Type:  721_B  Antibody Dilution:  1.0ug/ml 100 μL 2 to 3 Days
$289.00
Details
Human Goat Un-conjugated ELISA   100 μg 6 to 7 Days
$291.53
Details
Human Rabbit Un-conjugated WB 100 μL 11 to 14 Days
$537.17
Details
Bat Rabbit Un-conjugated WB 100 μL 11 to 14 Days
$551.83
Details
Human Mouse Un-conjugated ELISA, FACS, ICC, IHC, WB Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng) Western blot analysis using CBX7 mAb against human CBX7 (AA: 15-147) recombinant protein. (Expected MW is 41.3 kDa) 0.1 mg 3 to 4 Days
$430.10
Details
Human Rabbit Un-conjugated ELISA, WB 200 μL 12 to 14 Days
$438.90
Details
Human Rabbit Un-conjugated ELISA, IHC, WB 200 μL 12 to 14 Days
$438.90
Details
Cow Goat Un-conjugated ELISA   100 μg 11 to 14 Days
$507.83
Details
Human Mouse Un-conjugated WB Western Blot analysis of CBX7 expression in transfected 293T cell line by CBX7 MaxPab polyclonal antibody.Lane 1: CBX7 transfected lysate(27.61 KDa).Lane 2: Non-transfected lysate. CBX7 MaxPab polyclonal antibody. Western Blot analysis of CBX7 expression in Hela S3 NE. 50 μg 11 to 12 Days
$440.00
Details
Human Mouse Un-conjugated ELISA, FACS, IF/ICC, IHC, WB   100 μg 11 to 18 Days
$469.05
Details

More Antibodies against CBX7 Interaction Partners

Mouse (Murine) Chromobox Homolog 7 (CBX7) interaction partners

  1. Knockdown of CBX7 in either embryonic cortical neurons or adult dorsal root ganglion (DRG) neurons enhances their axon growth ability. Two important transcription factors GATA4 and SOX11 are functional downstream targets of CBX7 in controlling axon regeneration.

  2. CBX7 deficiency has a positive effect on tooth extraction socket healing.

  3. Here, by combining live-cell single-molecule tracking (SMT) and genetic engineering, the authors reveal that H3K27me3 contributes significantly to the targeting of Cbx7-PRC1 complex to chromatin.

  4. these results of this study suggest that CBX7 deficiency plays a positive role in dentin and alveolar bone formation.

  5. CD4(+) T cells express Cbx7; the latter prevents FasL expression and the activation-induced CD4(+) T cell apoptosis.

  6. Threonine 118 is a novel phosphorylation site of mouse Cbx7. Cbx7T118 phosphorylation moderately enhances repression of its target gene p16.

  7. Although the genomic localization of the Cbx7- and RYBP-containing PRC1 complexes overlaps in certain genes, it can also be mutually exclusive.

  8. MicroRNA regulation of Cbx7 mediates a switch of Polycomb orthologs during ESC differentiation.

  9. These data suggest that CBX7 is a tumor suppressor and that its loss plays a key role in the pathogenesis of cancer.

  10. controls cellular lifespan through regulation of both the p16(Ink4a)/Rb and the Arf/p53 pathways

  11. CBX7 is a chromobox protein causally linked to cancer development

Human Chromobox Homolog 7 (CBX7) interaction partners

  1. CBX7 positively regulates stem cell-like characteristics of gastric cancer cells by inhibiting p16 and activating AKT-NF-kappaB-miR-21 pathway.

  2. CBX7 and PRMT1 contribute to regulate E-cadherin expression through several mechanisms.

  3. Decreased CBX7 expression levels were correlated with liver cirrhosis in HCC patients. Furthermore, the survival times of HCC patients who were CBX7-expression-negative were shorter than HCC patients who were CBX7-expression-positive. Results show that downregulation of CBX7 is related to HCC progression and a poor prognosis in HCC patients.

  4. Study found that Cbx7 was downregulated in glioma cell lines and tumors and identifies it as an inhibitor of glioma cell migration through its inhibitory effect on YAP/TAZ-CTGF-hippo signaling axis and underscores the importance of epigenetic inactivation of Cbx7 in gliomagenesis.

  5. CBX7 inhibits epithelial-to-mesenchymal transformation and invasion in glioma

  6. our results validate the assumption that CBX7 is a tumor suppressor of gliomas. Moreover, CBX7 is a potential and novel prognostic biomarker in glioma patients. We also clarified that CBX7 silences CCNE1 via the combination of CCNE1 promoter and the recruitment of HDAC2.

  7. Suggest CBX7 is an important tumor suppressor that negatively modulates PTEN/Akt signaling during pancreatic tumorigenesis.

  8. Data suggest that miR-375 leads to the activation of oncogenic signatures and tumor progression by targeting chromobox homolog 7 protein (CBX7).

  9. the miR-9 family of microRNAs (miRNAS) downregulates the expression of CBX7. In turn, CBX7 represses miR-9-1 and miR-9-2 as part of a regulatory negative feedback loop.

  10. these results suggest that the retention of CBX7 expression may play a role in the modulation of chemosensitivity of lung cancer patients to the treatment with irinotecan and etoposide

  11. Data show that polycomb-group proteins BMI1, PHC3, CBX6 and CBX7 expression was significantly increased during imatinib treatment.

  12. Cbx7 is downregulated in CCs, and Cbx7 expression-low tumors correlated with lymph metastasis and poor overall survival of CC patients.

  13. CBX7/HMGA1b/NF-kappaB could take part in the same transcriptional mechanism that finally leads to the regulation of SPP1 gene expression in papillary thyroid carcinoma.

  14. Aberrantly expressed miR-9 contributes to T24 cells invasion, partly through directly down-regulating CBX7 protein expression in bladder transitional cell carcinoma

  15. Results suggest that the loss of CBX7 expression might play a critical role in advanced stages of carcinogenesis by deregulating the expression of specific effector genes.

  16. CBX7-mediated epigenetic induction of DKK-1 is crucial for the inhibition of breast tumorigenicity, suggesting that CBX7 could be a potential tumor suppressor in breast cancer.

  17. we showed for the first time that CBX7 was associated with a decreased prognosis for clear cell adenocarcinoma of the ovary

  18. cbx7 expression was significantly downregulated in multiple human cancer tissues.

  19. MicroRNA regulation of Cbx7 mediates a switch of Polycomb orthologs during ESC differentiation.

  20. These data suggest that CBX7 is a tumor suppressor and that its loss plays a key role in the pathogenesis of cancer.

CBX7 Antigen Profile

Protein Summary

human homolog interacts with Ring1 and localizes to nuclear Polycomb bodies

Gene names and symbols associated with CBX7

  • chromobox 7 (CBX7) antibody
  • chromobox 7 (Cbx7) antibody
  • chromobox homolog 7a (cbx7a) antibody
  • 1600014J01Rik antibody
  • AI851678 antibody
  • D15Ertd417e antibody
  • zgc:110152 antibody

Protein level used designations for CBX7

chromobox homolog 7 , chromobox protein homolog 7 , chromobox 7 , chromobox homolog 7a

GENE ID SPECIES
100340390 Oryctolagus cuniculus
52609 Mus musculus
362962 Rattus norvegicus
23492 Homo sapiens
481247 Canis lupus familiaris
100735098 Cavia porcellus
550551 Danio rerio
525770 Bos taurus
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