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Members of the coronin family, such as CORO1B, are WD repeat-containing actin-binding proteins that regulate cell motility (Cai et al., 2005 [PubMed 16027158]).[supplied by OMIM, Mar 2008].. Additionally we are shipping CORO1B Antibodies (55) and many more products for this protein.
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Cor1B, Cof1 and AIP1 work in concert through a temporally ordered pathway to induce highly efficient severing and disassembly of actin filaments.
Wt1 is a transcriptional activator of Coro1b gene.
Suggest that phosphorylation of Coro1B and the subsequent reduced interaction with ARP2/3 complex participate in PDGF-induced VSMC migration, an important step in vascular lesion formation.
Differential regulation of mast cell degranulation versus cytokine secretion by the actin regulatory proteins Coronin1a and Coronin1b.
VEGF-activated p38alpha phosphorylates coronin 1B at Ser2 and activates the Arp2/3 complex by liberating it from coronin 1B.
Coronin 1B constitutively binds to TGF beta receptor I in vascular smooth muscle cells.
The loss of junctional NMIIA, upon Coronin 1B knockdown, perturbed RhoA signaling.
When cells undergo apoptosis in an epithelial monolayer, coronin 1B is recruited to the junctional cortex at apoptotic/neighbor cell interface in an E-cadherin-dependent fashion to support actin architectural reorganization, contractility, and extrusion.
Coronin 1B regulates S1P-induced human lung endothelial cell chemotaxis.
analysis of the mechanism for negatively regulating Rho-kinase (ROCK) signaling through Coronin1B protein in neuregulin 1 (NRG-1)-induced tumor cell motility
Coronin 1B regulates leading edge dynamics and controls cell motility and interactions with the actin-related protein (Arp)2/3 complex
Study concludes that Coronin 1B's coordination of filament formation by Arp2/3 complex and filament turnover by Cofilin is required for effective lamellipodial protrusion and cell migration.
In rabbits, cholinergic stimulation increases the phosphorylation of coronin 1B in gastric mucosal cells
Members of the coronin family, such as CORO1B, are WD repeat-containing actin-binding proteins that regulate cell motility (Cai et al., 2005
coronin, actin binding protein, 1B
, coronin 1b
, coronin 2
, coronin 1B
, coronin, actin binding protein, 1B (coronin 2)
, coronin-like protein pp66