anti-Cyclin D Binding Myb-Like Transcription Factor 1 Antibodies

Protein Summary

This gene encodes a transcription factor that contains a cyclin D-binding domain, three central Myb-like repeats, and two flanking acidic transactivation domains at the N- and C-termini. The encoded protein is induced by the oncogenic Ras signaling pathway and functions as a tumor suppressor by activating the transcription of ARF and thus the ARF-p53 pathway to arrest cell growth or induce apoptosis. It also activates the transcription of aminopeptidase N and may play a role in hematopoietic cell differentiation. The transcriptional activity of this protein is regulated by binding of D-cyclins. This gene is hemizygously deleted in approximately 40% of human non-small-cell lung cancer and is a potential prognostic and gene-therapy target for non-small-cell lung cancer. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with DMTF1

• cyclin D binding myb like transcription factor 1 (DMTF1) antibody
• cyclin D binding myb-like transcription factor 1 (Dmtf1) antibody
• cyclin D binding myb like transcription factor 1 (dmtf1) antibody
• cyclin D binding myb-like transcription factor 1 (dmtf1) antibody
• cyclin D binding myb like transcription factor 1 (Dmtf1) antibody

• Dimp antibody
• Dmp1 antibody
• DMTF antibody
• DMTF1 antibody
• hDMP1 antibody
• Show all synonym aliases
• zgc:92448 antibody

Protein level used designations for DMTF1

cyclin D-binding Myb-like protein , cyclin-D-binding Myb-like transcription factor 1 , cyclin-D-interacting Myb-like protein 1 , hDMTF1 , D-interacting myb-like protein , cyclin D binding myb-like transcription factor 1D-interacting myb-like protein , mDmp1 , cyclin D binding myb-like transcription factor 1 , cyclin-D-binding Myb-like transcription factor 1-like