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CCNF encodes a member of the cyclin family. Additionally we are shipping Cyclin F Proteins (4) and many more products for this protein.
Showing 10 out of 63 products:
Human Monoclonal Cyclin F Primary Antibody for WB - ABIN967556
Bai, Richman, Elledge: Human cyclin F. in The EMBO journal 1995
Show all 4 Pubmed References
Our result indicates that the mutation of CCNF is rare in patients with amyotrophic lateral sclerosis and frontotemporal dementia from Mainland China
These data indicate that the coordinated, temporal ordering of cyclin F and Cdh1 (show CDH1 Antibodies) degradation, organized in a double-negative feedback loop, represents a fundamental aspect of cell-cycle control
Authors demonstrated a significant correlation between the severity of the CCNF-induced axonopathy and a reduced motor response to a light stimulus (photomotor response).
Cyclin F-mediated degradation of SLBP (show SLBP Antibodies) limits H2A.X (show H2AFX Antibodies) accumulation and apoptosis upon genotoxic stress in G2 cell cycle checkpoint.
cyclin F is a novel F-box protein (show FBXW10 Antibodies) that functions as an intrinsic cellular regulator of HIV-1 Vif (show BTG1 Antibodies) and has a negative regulatory effect on the maintenance of viral infectivity by restoring APOBEC3G (show APOBEC3G Antibodies) expression
The SCYL1- BP1 (show GORAB Antibodies) affects the cell cycle through increasing steady state levels of Cyclin F and RRM2 (show RRM2 Antibodies) proteins, thus constituting a dual regulatory circuit.
Data indicate that a missense mutation in cyclin F (CCNF) in a large Amyotrophic lateral sclerosis (ALS (show IGFALS Antibodies)) and frontotemporal dementia (FTD (show FTL Antibodies)) family.
CDC6 (show CDC6 Antibodies) and Cyclin F interact through defined sequence motifs that promote CDC6 (show CDC6 Antibodies) ubiquitylation and degradation.
Cyclin F suppresses B-Myb (show MYBL2 Antibodies) activity to promote cell cycle checkpoint control.
Cyclin F controls genome stability through ubiquitin-mediated proteolysis. (Review)
SCF (show KITLG Antibodies)(Cyclin F)-mediated degradation of CP110 (show CCP110 Antibodies) is required for the fidelity of mitosis and genome integrity
CycF(-/-) animals, with a myriad of developmental anomalies due in large part to failures in yolk sac (show ADCY10 Antibodies) and chorioallantoic placentation, die around embryonic day 10.5.
This gene encodes a member of the cyclin family. Cyclins are important regulators of cell cycle transitions through their ability to bind and activate cyclin-dependent protein kinases. This member also belongs to the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class and it was one of the first proteins in which the F-box motif was identified.
, cyclin F
, G2/mitotic-specific cyclin-F
, G2/mitotic-specific cyclin-F-like
, g2/mitotic-specific cyclin-F-like
, F-box only protein 1