anti-Cyclin T2 (CCNT2) Antibodies

The protein encoded by CCNT2 belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Additionally we are shipping Cyclin T2 Kits (12) and Cyclin T2 Proteins (4) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
CCNT2 905 O60583
CCNT2 72949  
CCNT2 304758  
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Top anti-Cyclin T2 Antibodies at antibodies-online.com

Showing 10 out of 36 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated ICC, IF, IHC (p), WB WB Image Sample (30 ug of whole cell lysate) A: Hep G2 , 7.5% SDS PAGE antibody diluted at 1:1000 ICC/IF Image Immunofluorescence analysis of paraformaldehyde-fixed A431, using cyclin T2, antibody at 1:200 dilution. 100 μL Log in to see 3 to 4 Days
$466.18
Details
Human Rabbit Un-conjugated ELISA, WB 100 μL Log in to see 11 to 14 Days
$639.83
Details
Human Rabbit Un-conjugated ELISA, WB Western blot analysis of CCNT2 expression in HepG2 whole cell lysate ,The lane on the left is treated with the antigen-specific peptide. 100 μL Log in to see 11 to 12 Days
$390.77
Details
Human Rabbit Un-conjugated ELISA, WB   100 μL Log in to see 11 to 13 Days
$335.04
Details
Human Rabbit Un-conjugated ICC, IHC, IHC (p), WB   100 μL Log in to see 11 to 14 Days
$537.17
Details
Human Mouse Un-conjugated DB, WB   50 μg Log in to see 11 to 14 Days
$493.17
Details
Human Mouse Un-conjugated ELISA, WB   100 μg Log in to see 11 to 14 Days
$537.17
Details
Human Rabbit Alexa Fluor 488 IF (p)   100 μL Log in to see 14 to 21 Days
$416.90
Details
Human Rabbit Cy5.5 IF (p)   100 μL Log in to see 14 to 21 Days
$416.90
Details
Human Rabbit HRP IHC (p), WB   100 μL Log in to see 14 to 21 Days
$416.90
Details

Top referenced anti-Cyclin T2 Antibodies

  1. Polyclonal Cyclin T2 Primary Antibody for IP, ELISA - ABIN539516 : Nguyen, Kiss, Michels, Bensaude: 7SK small nuclear RNA binds to and inhibits the activity of CDK9/cyclin T complexes. in Nature 2001 (PubMed)
    Show all 3 Pubmed References

  2. Human Polyclonal Cyclin T2 Primary Antibody for IHC, IHC (p) - ABIN4301639 : Shiozaki, Okamura, Kohno, Keenan, Williams, Zhao, Chick, Miyazaki-Anzai, Miyazaki: The CDK9-cyclin T1 complex mediates saturated fatty acid-induced vascular calcification by inducing expression of the transcription factor CHOP. in The Journal of biological chemistry 2018 (PubMed)

More Antibodies against Cyclin T2 Interaction Partners

Human Cyclin T2 (CCNT2) interaction partners

  1. Physical interaction between pRb and cdk9/cyclinT2 complex.

  2. miR-192 inhibits cell proliferation and induces G0/G1 cell cycle arrest in AML by regulating the expression of CCNT2.

  3. the release of P-TEFb from the 7SK snRNP led to increased synthesis of HEXIM1 but not HEXIM2

  4. CycT2 not only contains two domains that target rna polymerase II but this substrate recognition is necessary for its transcriptional activity via DNA

  5. Data strengthen the hypothesis that Cyclin T2a plays a role in muscle differentiation, and propose PKNalpha as a novel partner of Cyclin T2a in this process.

  6. The results establish that cdk9/cyclin T2a-mediated coactivation of MyoD depends on serine 37 phosphorylation.

  7. These results suggest that acetylation of CDK9 is an important posttranslational modification that is involved in regulating P-TEFb transcriptional elongation function.

  8. TAF7 interacts with the transcription factors, TFIIH and P-TEFb, resulting in the inhibition of their Pol II CTD kinase activities

  9. The tripartite protein-RNA complex formation between Hexim, Cyclin T and 7SK snRNA, was analyzed.

Mouse (Murine) Cyclin T2 (CCNT2) interaction partners

  1. both isoforms of Cyclin T2 are able to activate the myogenic program but Cyclin T2b has a predominant role, in particular during the latest stages.

  2. miR-15a inhibited muscle differentiation at least in part by targeting Ccnt2; roles in spermatogenesis.

  3. activation of MyoD-dependent transcription by cdk9/cyclin T2

  4. despite numerous matings of heterozygous mice, we observed no CycT2(-/-) embryos, pups, or adult mice. This early lethality could have resulted from decreased expression of critical genes

Cyclin T2 (CCNT2) Antigen Profile

Protein Summary

The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin and its kinase partner CDK9 were found to be subunits of the transcription elongation factor p-TEFb. The p-TEFb complex containing this cyclin was reported to interact with, and act as a negative regulator of human immunodeficiency virus type 1 (HIV-1) Tat protein. A pseudogene of this gene is found on chromosome 1. Alternate splicing results in multiple transcript variants.

Gene names and symbols associated with anti-Cyclin T2 (CCNT2) Antibodies

  • cyclin T2 (CCNT2) antibody
  • cyclin T2b (ccnt2b) antibody
  • cyclin T2a (ccnt2a) antibody
  • cyclin T2 S homeolog (ccnt2.S) antibody
  • cyclin T2 (ccnt2) antibody
  • cyclin T2 (Ccnt2) antibody
  • 2900041I18Rik antibody
  • C81304 antibody
  • CCNT2 antibody
  • cycT antibody
  • CycT2 antibody
  • CycT2b antibody
  • fb16c03 antibody
  • MGC81210 antibody
  • wu:fb16c03 antibody
  • wu:fi17h07 antibody
  • wu:fj68b10 antibody
  • zgc:55357 antibody
  • zgc:55690 antibody

Protein level used designations for anti-Cyclin T2 (CCNT2) Antibodies

cyclin T2 , cyclin-T2 , cyclin-T2-like , SDS-stable vimentin-bound DNA fragment HEF42VIM22 , cyclin T2a , cyclin T2b , subunit of positive elongation transcription factor b

GENE ID SPECIES
100050510 Equus caballus
321464 Danio rerio
327568 Danio rerio
447439 Xenopus laevis
470546 Pan troglodytes
476126 Canis lupus familiaris
100349398 Oryctolagus cuniculus
100412841 Callithrix jacchus
100446291 Pongo abelii
100488125 Xenopus (Silurana) tropicalis
100011986 Monodelphis domestica
100552048 Anolis carolinensis
100599933 Nomascus leucogenys
905 Homo sapiens
424289 Gallus gallus
521089 Bos taurus
72949 Mus musculus
304758 Rattus norvegicus
101106913 Ovis aries
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