Cyclin T2 antibody

Catalog No. ABIN930980

The Mouse Monoclonal anti-Cyclin T2 antibody is suitable to detect Cyclin T2 in samples from Human. It has been validated for WB and DB.

Quick Overview for Cyclin T2 antibody (ABIN930980)

Target: Cyclin T2 (CCNT2)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Cyclin T2 antibody is un-conjugated

Application: Western Blotting (WB), Dot Blot (DB)

Clone: 2128C1a

Product Details anti-Cyclin T2 Antibody

Cross-Reactivity: Human

Cross-Reactivity (Details): Other species not studied.

Purification: Protein G affinity chromatography

Immunogen: CCNT2 antibody was raised in mouse using recombinant Human Cyclin T2 (Ccnt2), Transcript Variant B

Isotype: IgG1

Application Details

Application Notes: WB: 0.2-2 µg/mL
Optimal conditions should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: Lot specific

Buffer: CCNT2 antibody in PBS (3.0 mM KCl, 1.5 mM KH2 PO4 , 140 mM NaCl, 8.0 mM Na2 HPO4 (pH 7.4)) containing 1 % bovine serum albumin (BSA) and 0.05 % sodium azide (NaN3 ).

Preservative: Sodium azide

Precaution of Use: This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Storage: 4 °C/-20 °C

Storage Comment: Store at 2-8 °C for up to one year. We recommend long term storage at -20 °C.

Target Details for Cyclin T2

Target: Cyclin T2 (CCNT2)

Alternative Name: CCNT2

Background: The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin and its kinase partner CDK9 were found to be subunits of the transcription elongation factor p-TEFb. The p-TEFb complex containing this cyclin was reported to interact with, and act as a negative regulator of human immunodeficiency virus type 1 (HIV-1) Tat protein. Two alternatively spliced transcript variants, which encode distinct isoforms, have been described. Synonyms: Monoclonal CCNT2 antibody, Anti-CCNT2 antibody, Cyclin T2 antibody, FLJ90560 antibody, MGC134840 antibody.