anti-Cyclin-Dependent Kinase 10 (CDK10) Antibodies

The protein encoded by CDK10 belongs to the CDK subfamily of the Ser/Thr protein kinase family. Additionally we are shipping CDK10 Proteins (6) and and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
CDK10 8558 Q15131
CDK10 234854 Q3UMM4
CDK10 361434 Q4KM47
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Top anti-CDK10 Antibodies at antibodies-online.com

Showing 10 out of 104 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated IHC (p), WB Western blot analysis of CDK10 antibody (N-term) (ABIN391741) pre-incubated with (Lane1) and without (Lane 2) blocking peptide (BP7516a) in A375 cell line lysate. CDK10 (arrow) was detected using the purified polyclonal antibody. Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. BC = breast carcinoma. HC = hepatocarcinoma 400 μL Log in to see 10 to 11 Days
$385.00
Details
Cow Rabbit Un-conjugated IHC, WB Immunohistochemical analysis of CDK10 staining in human brain formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. Western blot analysis of CDK10 expression in Jurkat (A) whole cell lysates. 200 μL Log in to see 13 to 14 Days
$487.50
Details
Human Rabbit Un-conjugated ELISA, WB Western blot analysis of extracts from 293 cells, using CDK10 Antibody. The lane on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Goat Un-conjugated ELISA, WB   100 μg Log in to see 6 to 7 Days
$429.84
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. Western blot analysis of anti-CDK10 Pab in A375 cell lysate. CDK10 (arrow) was detected using purified Pab. Secondary HRP-anti-rabbit was used for signal visualization with chemiluminescence. 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated ELISA, IHC, WB Western Blot (WB) analysis of specific cells using Cdk10 Polyclonal Antibody. 100 μL Log in to see 16 Days
$181.73
Details
Human Rabbit Un-conjugated ELISA, ICC, IF, WB Western blot analysis of extracts from 293 cells, using CDK10 antibody. ABIN6274362 staining 293 cells by IF/ICC. The sample were fixed with PFA and permeabilized in 0.1% Triton X-100,then blocked in 10% serum for 45 minutes at 25°C. The primary antibody was diluted at 1/200 and incubated with the sample for 1 hour at 37°C. An Alexa Fluor 594 conjugated goat anti-rabbit IgG (H+L) antibody(Cat.# S0006), diluted at 1/600, was used as secondary antibody. 100 μL Log in to see 11 to 12 Days
$390.77
Details
Human Rabbit Un-conjugated WB Mouse Cdk10 Antibody (C-term) western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the Cdk10 antibody detected the Cdk10 protein (arrow). 400 μL Log in to see 10 to 11 Days
$385.00
Details
Mouse Goat Un-conjugated ELISA, WB 0.1 mg Log in to see 2 to 3 Days
$515.63
Details
Human Goat Un-conjugated WB   0.1 mg Log in to see 8 to 11 Days
$462.00
Details

Top referenced anti-CDK10 Antibodies

  1. Human Polyclonal CDK10 Primary Antibody for IHC (p), WB - ABIN391741 : Leman, Magheli, Yong, Netto, Hinz, Getzenberg: Identification of nuclear structural protein alterations associated with seminomas. in Journal of cellular biochemistry 2009 (PubMed)
    Show all 12 Pubmed References

  2. Human Polyclonal CDK10 Primary Antibody for ELISA, WB - ABIN541986 : Iorns, Turner, Elliott, Syed, Garrone, Gasco, Tutt, Crook, Lord, Ashworth: Identification of CDK10 as an important determinant of resistance to endocrine therapy for breast cancer. in Cancer cell 2008 (PubMed)

More Antibodies against CDK10 Interaction Partners

Human Cyclin-Dependent Kinase 10 (CDK10) interaction partners

  1. The present study illustrated that downregulation of CDK10 expression activated Snaildriven EMT and consequently promoted glioma metastasis, suggesting that CDK10 may serve as a potential molecular target for glioma therapy.

  2. the results of the present study indicated that CDK10 expression may serve as a novel prognostic biomarker that holds therapeutic promise for gastric cancer.

  3. The findings of this study indicate that CDK10 plays a role in the pathogenesis in colorectal cancer and may be a potential therapeutic target for treatment.

  4. These findings underscore the importance of CDK10 for the regulation of ciliogenesis. CDK10 defect is likely associated with a new form of ciliopathy phenotype; additional patients may further validate this association

  5. CDK10 Mutations are associated with Severe Growth Retardation, Spine Malformations, and Developmental Delays.

  6. CDK10/CycM is a key regulator of actin dynamics and a suppressor of ciliogenesis through phosphorylation of PKN2 and promotion of RhoA signaling.

  7. Down-regulated CDK10 expression frequently occurs in breast cancers and correlates with disease progression and poor survival

  8. Results found that CDK10 mRNA expression was up-regulated in advanced breast neoplasm and positively correlated with C1orf63, which was consistent with the relationship of protein expression between C1orf63 and CDK10.

  9. Data suggest that reactivation of CDK10 might be utilized as a novel epigenetic strategy for the treatment of nasopharyngeal carcinomas (NPC) patients.

  10. CDK10/cyclin M is a protein kinase that controls ETS2 degradation and is deficient in STAR syndrome.

  11. Data show that peptidyl-prolyl isomerase Pin1 silencing in SKBR-3 and MCF7 cells increased the cyclin-dependent kinase 10 (CDK10) expression.

  12. CDK10 plays a crucial role in the growth and survivability of biliary tract cancer.

  13. reduced Cdk10 expression is closely linked to hepatocellular carcinoma development and progression

  14. CDK10 is not a target for aberrant DNA methylation in breast cancer.

Mouse (Murine) Cyclin-Dependent Kinase 10 (CDK10) interaction partners

  1. CDK10 Mutations are associated with Severe Growth Retardation, Spine Malformations, and Developmental Delays.

  2. Data indicate that peptidyl-prolyl isomerase Pin1(-/-) mouse embryonic fibroblasts (MEFs) showed higher cyclin-dependent kinase 10 (CDK10) expression than Pin1(+/+) MEFs.

  3. Data show that murine cdk10 binds Ets2 transcription factors in vitro, does not show a direct involvement in the G2/M transition and, therefore, does not affect the proliferation rate of the cell lines analyzed.

  4. Discusses PISSLRE, the human ortholog of mouse cyclin-dependent kinase 10.

Zebrafish Cyclin-Dependent Kinase 10 (CDK10) interaction partners

  1. cdk10 has roles in vertebrate development and a critical function in neurogenesis by modulation of raf1a expression

CDK10 Antigen Profile

Protein Summary

The protein encoded by this gene belongs to the CDK subfamily of the Ser/Thr protein kinase family. The CDK subfamily members are highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2, and are known to be essential for cell cycle progression. This kinase has been shown to play a role in cellular proliferation and its function is limited to cell cycle G2-M phase. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with CDK10

  • cyclin dependent kinase 10 (CDK10) antibody
  • cyclin-dependent kinase 10 (Cdk10) antibody
  • cyclin-dependent kinase 10 (cdk10) antibody
  • cyclin-dependent kinase 10 (LOC5566134) antibody
  • CDK family protein kinase (cdk10) antibody
  • hypothetical protein (Cdk10) antibody
  • cyclin-dependent kinase 10 L homeolog (cdk10.L) antibody
  • BC017131 antibody
  • cdc2rk antibody
  • DDBDRAFT_0216532 antibody
  • DDBDRAFT_0229427 antibody
  • DDB_0216532 antibody
  • DDB_0229427 antibody
  • NV16107 antibody
  • PISSLRE antibody
  • zgc:110252 antibody

Protein level used designations for CDK10

CDC2-related protein kinase , cell division protein kinase 10 , cyclin-dependent kinase (CDC2-like) 10 , cyclin-dependent kinase related protein , serine/threonine protein kinase PISSLRE , serine/threonine-protein kinase PISSLRE , cyclin dependent kinase 10 , cdk10/11 , PITSLRE subfamily protein kinase , protein kinase, CMGC group , cyclin-dependent kinase 10 , cell division protein kinase 10-like , hypothetical protein , cdc2-related-kinase

GENE ID SPECIES
8558 Homo sapiens
234854 Mus musculus
489655 Canis lupus familiaris
550285 Danio rerio
5566134 Aedes aegypti
8615914 Dictyostelium discoideum AX4
100465613 Ailuropoda melanoleuca
361434 Rattus norvegicus
415840 Gallus gallus
549329 Xenopus (Silurana) tropicalis
615171 Bos taurus
700096 Macaca mulatta
5887315 Monosiga brevicollis MX1
100027293 Monodelphis domestica
100036925 Xenopus laevis
100052321 Equus caballus
100113820 Nasonia vitripennis
100233178 Sus scrofa
100392288 Callithrix jacchus
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