anti-Cysteine-Rich Secretory Protein 2 (CRISP2) Antibodies

May regulate some ion channels' activity and therebye regulate calcium fluxes during sperm capacitation.. Additionally we are shipping CRISP2 Kits (10) and CRISP2 Proteins (7) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
CRISP2 22024 P16563
CRISP2 360445  
CRISP2 7180 P16562
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Top anti-CRISP2 Antibodies at antibodies-online.com

Showing 10 out of 68 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Goat Un-conjugated ELISA, IHC, WB HEK293 lysate (10ug protein in RIPA buffer) overexpressing Human CRISP2 (RC205312) with C-terminal MYC tag probed with ABIN571121 (1ug/ml) in Lane A and probed with anti-MYC Tag (1/1000) in lane C. Mock-transfected HEK293 probed with ABIN571121 (1mg/ml) in Lane 100 μg Log in to see 6 to 7 Days
$429.84
Details
Please inquire Goat Un-conjugated ELISA, WB   100 μg Log in to see 6 to 7 Days
$429.84
Details
Human Goat Un-conjugated ELISA, WB 0.1 mg Log in to see 2 to 3 Days
$515.63
Details
Human Goat Un-conjugated ELISA, IHC, IHC (p) Anti-CRISP-2 / TSP1 antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 3.75 ug/ml. 50 μg Log in to see 11 to 14 Days
$484.00
Details
Dog Goat Un-conjugated EIA, WB HEK293 lysate (10µg protein in RIPA buffer) overexpressing Human CRISP2 with C-terminal MYC tag probed with AP21265PU-N CRISP2 Antibody (1 µg/ml) in Lane A and probed with anti-MYC Tag (1/1000) in lane C. Mock-transfected HEK293 probed with AP21265PU-N (1 mg/ml) in Lane B. Primary incubations were for 1 hour. Detected by chemiluminescence. 0.1 mg Log in to see 6 to 8 Days
$445.50
Details
Human Rabbit Un-conjugated ICC, IF, IHC, IHC (p), WB Immunohistochemistry-Paraffin: CRISP2 Antibody [NBP1-85452] - Staining of human testis shows strong nuclear and cytoplasmic positivity in cells in seminiferus ducts. Western Blot: CRISP2 Antibody [NBP1-85452] - Lane 1: Marker [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10.Lane 2: Negative control (vector only transfected HEK293T lysate).Lane 3: Over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (~3.1 kDa) in mammalian HEK293T cells, LY418782) 0.1 mL Log in to see 10 to 13 Days
$494.38
Details
Human Rabbit Un-conjugated IHC, WB Western blot analysis of extracts of human testis tissue, using CRISP2 antibody. 100 μL Log in to see 11 to 12 Days
$390.77
Details
Human Rabbit Un-conjugated ELISA, IHC, IHC (p), WB Human Testis: Formalin-Fixed, Paraffin-Embedded (FFPE) Anti-CRISP2 antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml. 50 μg Log in to see 11 to 14 Days
$484.00
Details
Human Rabbit Un-conjugated EIA, WB   0.1 mg Log in to see 4 to 8 Days
$522.50
Details
Human Rabbit Un-conjugated ICC, IHC, WB Figure. Western Blot; Sample: Recombinant protein. Figure.DAB staining on IHC-P. Samples: Human Tissue 100 μg Log in to see 13 to 16 Days
$350.00
Details

Top referenced anti-CRISP2 Antibodies

  1. Dog (Canine) Polyclonal CRISP2 Primary Antibody for ELISA, WB - ABIN4300508 : Jamsai, Reilly, Smith, Gibbs, Baker, McLachlan, de Kretser, OBryan: Polymorphisms in the human cysteine-rich secretory protein 2 (CRISP2) gene in Australian men. in Human reproduction (Oxford, England) 2008 (PubMed)

More Antibodies against CRISP2 Interaction Partners

Mouse (Murine) Cysteine-Rich Secretory Protein 2 (CRISP2) interaction partners

  1. Crisp2 genetic defects in sperm from humans and mice result in male infertility.

  2. expression and localization of SHTAP in testis and sperm raise the possibility that the SHTAP-CRISP2 complex has a potential role in sperm formation and/or function.

  3. Tpx-1 Crisp domain on its own can regulate ion channel activity and provide compelling evidence for a role for Tpx-1 in the regulation of Ca(2+) fluxes observed during sperm capacitation.

  4. Evidence for a functional role of CRISP2 in fertilization.

  5. These data raise the possibility that CRISP2 is a MAP3K11-modifying protein or, alternatively, that MAP3K11 acts to phosphorylate CRISP2 during acrosome development.

Human Cysteine-Rich Secretory Protein 2 (CRISP2) interaction partners

  1. The integrated network analysis identified BRCA1 and CRISP2 differentially methylated regions (DMR) as the most central disease-associated DNA methylation biomarkers. Moreover, methylation changes at BRCA1 and CRISP2 specific CpG sites were consistently associated with subclinical atherosclerosis measures.

  2. low expression of CRISP2 protein rather than its mRNA was observed in the ejaculated spermatozoa from asthenoteratozoospermic patients as compared with normozoospermic males

  3. Results identified CRISP2 as a potential binding protein of PSP94 from human sperm.

  4. Crisp2 genetic defects in sperm from humans and mice result in male infertility.

  5. Preliminary insight into the mechanism leading to the reduced CRISP2 expression in asthenozoospermia, offering a potential therapeutic target for treating male infertility or for male contraception.

  6. Study shows the re-association of sperm acrosomal CRISP2 at the EqS during the acrosome reaction. Data showed that F-actin is not involved in the relocalization of CRISP2. Found that basic,but not acidic, conditions can solubilize CRISP2 from sperm cells.

  7. CRISP2 rescues the phenotype of yeast mutants lacking Pry function and purified CRISP2 binds cholesterol in vitro, indicating that lipid binding is a conserved function of the CAP superfamily proteins.

  8. The down-regulation of CRISP2 mRNA and protein expressions in the sperm of asthenospermia patients may be closely related with decreased sperm motility.

  9. Additional transcription changes likely associated with Th2-like eosinophilic inflammation were prominent and included decreased CRISP2&3.

  10. TPX1 is a component of the sperm acrosome that remains associated with sperm after capacitation and acrosome reaction , and is relevant for sperm-oocyte interaction.

  11. The protein level and localization of TPX1 were altered in patients with spermatogenic arrest and in infertile men with oligoasthenoteratospermia syndrome.

  12. Polymorphisms within the CRISP2 gene have no significant association with male infertility.

Cow (Bovine) Cysteine-Rich Secretory Protein 2 (CRISP2) interaction partners

  1. CRISP2 mRNA levels are associated with male fertility.

CRISP2 Antigen Profile

Protein Summary

May regulate some ion channels' activity and therebye regulate calcium fluxes during sperm capacitation.

Gene names and symbols associated with CRISP2

  • cysteine-rich secretory protein 2 L homeolog (crisp2.L) antibody
  • cysteine rich secretory protein 2 (CRISP2) antibody
  • cysteine-rich secretory protein 2 (CRISP2) antibody
  • cysteine-rich secretory protein 2 (Crisp2) antibody
  • crisp antibody
  • CRISP-1 antibody
  • CRISP-2 antibody
  • CRISP-3 antibody
  • Crisp2 antibody
  • Crisp2l antibody
  • CRISP3 antibody
  • CT36 antibody
  • GAPDL5 antibody
  • Tpx-1 antibody
  • TPX1 antibody
  • TSP1 antibody

Protein level used designations for CRISP2

cysteine-rich secretory protein 2 , cysteine rich secretory protein , cysteine-rich secretory protein 3 , cystein-rich secretory protein 2 , cysteine-rich secretory protein-2 , testis specific gene 1 , testis-specific protein TPX-1 , cysteine-rich secretory protein 2-like , testis specific protein 1 , cancer/testis antigen 36 , glyceraldehyde-3-phosphate dehydrogenase-like 5 , testis specific protein 1 (probe H4-1 p3-1) , cysteine-rich secretory protein-3 , cysteine-rich secretory protein 1 , autoantigen 1

GENE ID SPECIES
398591 Xenopus laevis
422045 Gallus gallus
462756 Pan troglodytes
706747 Macaca mulatta
100034138 Equus caballus
100462690 Ovis aries
22024 Mus musculus
360445 Rattus norvegicus
7180 Homo sapiens
474932 Canis lupus familiaris
397369 Sus scrofa
512443 Bos taurus
100135505 Cavia porcellus
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