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May regulate some ion channels' activity and therebye regulate calcium fluxes during sperm capacitation.. Additionally we are shipping CRISP2 Kits (9) and CRISP2 Proteins (7) and many more products for this protein.
Showing 10 out of 61 products:
Cow (Bovine) Polyclonal CRISP2 Primary Antibody for ELISA, WB - ABIN4300509
Jamsai, Reilly, Smith, Gibbs, Baker, McLachlan, de Kretser, OBryan: Polymorphisms in the human cysteine-rich secretory protein 2 (CRISP2) gene in Australian men. in Human reproduction (Oxford, England) 2008
Crisp2 genetic defects in sperm from humans and mice result in male infertility.
expression and localization of SHTAP (show NSUN4 Antibodies) in testis and sperm raise the possibility that the SHTAP (show NSUN4 Antibodies)-CRISP2 complex has a potential role in sperm formation and/or function.
Tpx-1 Crisp domain on its own can regulate ion channel activity and provide compelling evidence for a role for Tpx-1 in the regulation of Ca(2 (show CA2 Antibodies)+) fluxes observed during sperm capacitation.
Evidence for a functional role of CRISP2 in fertilization.
These data raise the possibility that CRISP2 is a MAP3K11 (show MAP3K11 Antibodies)-modifying protein or, alternatively, that MAP3K11 (show MAP3K11 Antibodies) acts to phosphorylate CRISP2 during acrosome development.
Results identified CRISP2 as a potential binding protein of PSP94 (show MSMB Antibodies) from human sperm.
Preliminary insight into the mechanism leading to the reduced CRISP2 expression in asthenozoospermia, offering a potential therapeutic target for treating male infertility or for male contraception.
Study shows the re-association of sperm acrosomal CRISP2 at the EqS during the acrosome reaction. Data showed that F-actin is not involved in the relocalization of CRISP2. Found that basic,but not acidic, conditions can solubilize CRISP2 from sperm cells.
CRISP2 rescues the phenotype of yeast mutants lacking Pry (show PRY Antibodies) function and purified CRISP2 binds cholesterol in vitro, indicating that lipid binding is a conserved function of the CAP superfamily proteins.
The down-regulation of CRISP2 mRNA and protein expressions in the sperm of asthenospermia patients may be closely related with decreased sperm motility.
Additional transcription changes likely associated with Th2-like eosinophilic inflammation were prominent and included decreased CRISP2&3.
TPX1 (show PRDX2 Antibodies) is a component of the sperm acrosome that remains associated with sperm after capacitation and acrosome reaction , and is relevant for sperm-oocyte interaction.
The protein level and localization of TPX1 (show PRDX2 Antibodies) were altered in patients with spermatogenic arrest and in infertile men with oligoasthenoteratospermia syndrome.
Polymorphisms within the CRISP2 gene have no significant association with male infertility.
CRISP2 mRNA levels are associated with male fertility.
May regulate some ion channels' activity and therebye regulate calcium fluxes during sperm capacitation.
cysteine-rich secretory protein 2
, cysteine rich secretory protein
, cysteine-rich secretory protein 3
, cystein-rich secretory protein 2
, cysteine-rich secretory protein-2
, testis specific gene 1
, testis-specific protein TPX-1
, cysteine-rich secretory protein 2-like
, testis specific protein 1
, cancer/testis antigen 36
, glyceraldehyde-3-phosphate dehydrogenase-like 5
, testis specific protein 1 (probe H4-1 p3-1)
, cysteine-rich secretory protein-3
, cysteine-rich secretory protein 1
, autoantigen 1