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CRISP2 antibody (N-Term)

CRISP2 Reactivity: Human WB, EIA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN783679
  • Target See all CRISP2 Antibodies
    CRISP2 (Cysteine-Rich Secretory Protein 2 (CRISP2))
    Binding Specificity
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivity
    • 11
    • 3
    • 3
    Human
    Host
    • 8
    • 2
    • 2
    Rabbit
    Clonality
    • 11
    • 1
    Polyclonal
    Conjugate
    • 12
    This CRISP2 antibody is un-conjugated
    Application
    • 11
    • 8
    • 8
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    Specificity
    This antibody detects CRISP2 at N-term.
    Cross-Reactivity (Details)
    Species reactivity (tested):Human
    Purification
    Affinity chromatography purified via peptide column
    Immunogen
    15 amino acid peptide near the amino terminus of human CRISP2
    Top Product
    Discover our top product CRISP2 Primary Antibody
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Buffer
    PBS containing 0.02 % sodium azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.
  • Target
    CRISP2 (Cysteine-Rich Secretory Protein 2 (CRISP2))
    Alternative Name
    CRISP2 (CRISP2 Products)
    Synonyms
    ct36 antibody, tpx1 antibody, tsp1 antibody, crisp antibody, gapdl5 antibody, crisp-2 antibody, CRISP3 antibody, CRISP2 antibody, CRISP-2 antibody, GAPDL5 antibody, Tpx-1 antibody, Tpx1 antibody, Crisp2l antibody, CT36 antibody, TPX1 antibody, TSP1 antibody, CRISP-3 antibody, CRISP-1 antibody, Crisp2 antibody, cysteine-rich secretory protein 2 L homeolog antibody, cysteine rich secretory protein 2 antibody, cysteine-rich secretory protein 2 antibody, crisp2.L antibody, CRISP2 antibody, Crisp2 antibody
    Background
    The cysteine-rich secretory proteins (CRISP) family is a group of four proteins that are strongly expressed in the male reproductive tract and have been implicated in having roles in male fertility. CRISP2, also known as TPX1, has been implicated in the adhesion between spermatids and Sertoli cells, and with CRISP1, is thought to be involved in sperm-egg fusion. CRISP2 has been shown to regulate the Ca2+ influx through ryanodine receptors (RYR) and may influence the acrosome reaction or sperm motility. CRISP2 has also been shown to bind to the mitogen-activated protein kinase kinase kinase 11 (MAP3K11) and localizes to the developing acrosome, suggesting this CRISP2-MAP3K11 complex may have a role in acrosome development.Synonyms: CRISP-2, CT36, Cancer/testis antigen 36, Cysteine-rich secretory protein 2, GAPDL5, TPX1, Testis-specific protein TPX-1
    Gene ID
    7180
    NCBI Accession
    NP_001135879
    UniProt
    P16562
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