Cysteine-Rich Secretory Protein 2 Proteins (CRISP2)

May regulate some ion channels' activity and therebye regulate calcium fluxes during sperm capacitation..

list all proteins Gene Name GeneID UniProt
Mouse CRISP2 CRISP2 22024 P16563
Rat CRISP2 CRISP2 360445  
Human CRISP2 CRISP2 7180 P16562
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Top CRISP2 Proteins at antibodies-online.com

Showing 7 out of 7 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
$5,960.83
Details
Insect Cells Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
$5,960.83
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Wheat germ Human GST tag 10 μg Log in to see 11 to 12 Days
$414.29
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Yeast REACT_Pitviper His tag   1 mg Log in to see 60 to 71 Days
$2,548.33
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Yeast Guinea Pig His tag   1 mg Log in to see 60 to 71 Days
$2,557.50
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Escherichia coli (E. coli) Human T7 tag,His tag 100 μg Log in to see 15 to 18 Days
$733.00
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Human Human His tag   10 μg Log in to see 15 to 16 Days
$225.00
Details

More Proteins for Cysteine-Rich Secretory Protein 2 (CRISP2) Interaction Partners

Mouse (Murine) Cysteine-Rich Secretory Protein 2 (CRISP2) interaction partners

  1. Crisp2 genetic defects in sperm from humans and mice result in male infertility.

  2. expression and localization of SHTAP (show NSUN4 Proteins) in testis and sperm raise the possibility that the SHTAP (show NSUN4 Proteins)-CRISP2 complex has a potential role in sperm formation and/or function.

  3. Tpx-1 Crisp domain on its own can regulate ion channel activity and provide compelling evidence for a role for Tpx-1 in the regulation of Ca(2 (show CA2 Proteins)+) fluxes observed during sperm capacitation.

  4. Evidence for a functional role of CRISP2 in fertilization.

  5. These data raise the possibility that CRISP2 is a MAP3K11 (show MAP3K11 Proteins)-modifying protein or, alternatively, that MAP3K11 (show MAP3K11 Proteins) acts to phosphorylate CRISP2 during acrosome development.

Human Cysteine-Rich Secretory Protein 2 (CRISP2) interaction partners

  1. low expression of CRISP2 protein rather than its mRNA was observed in the ejaculated spermatozoa from asthenoteratozoospermic patients as compared with normozoospermic males

  2. Results identified CRISP2 as a potential binding protein of PSP94 (show MSMB Proteins) from human sperm.

  3. Crisp2 genetic defects in sperm from humans and mice result in male infertility.

  4. Preliminary insight into the mechanism leading to the reduced CRISP2 expression in asthenozoospermia, offering a potential therapeutic target for treating male infertility or for male contraception.

  5. Study shows the re-association of sperm acrosomal CRISP2 at the EqS during the acrosome reaction. Data showed that F-actin is not involved in the relocalization of CRISP2. Found that basic,but not acidic, conditions can solubilize CRISP2 from sperm cells.

  6. CRISP2 rescues the phenotype of yeast mutants lacking Pry function and purified CRISP2 binds cholesterol in vitro, indicating that lipid binding is a conserved function of the CAP superfamily proteins.

  7. The down-regulation of CRISP2 mRNA and protein expressions in the sperm of asthenospermia patients may be closely related with decreased sperm motility.

  8. Additional transcription changes likely associated with Th2-like eosinophilic inflammation were prominent and included decreased CRISP2&3.

  9. TPX1 (show PRDX2 Proteins) is a component of the sperm acrosome that remains associated with sperm after capacitation and acrosome reaction , and is relevant for sperm-oocyte interaction.

  10. The protein level and localization of TPX1 (show PRDX2 Proteins) were altered in patients with spermatogenic arrest and in infertile men with oligoasthenoteratospermia syndrome.

Cow (Bovine) Cysteine-Rich Secretory Protein 2 (CRISP2) interaction partners

  1. CRISP2 mRNA levels are associated with male fertility.

CRISP2 Protein Profile

Protein Summary

May regulate some ion channels' activity and therebye regulate calcium fluxes during sperm capacitation.

Gene names and symbols associated with CRISP2

  • cysteine-rich secretory protein 2 L homeolog (crisp2.L)
  • cysteine rich secretory protein 2 (CRISP2)
  • cysteine-rich secretory protein 2 (CRISP2)
  • cysteine-rich secretory protein 2 (Crisp2)
  • crisp protein
  • CRISP-1 protein
  • CRISP-2 protein
  • CRISP-3 protein
  • Crisp2 protein
  • Crisp2l protein
  • CRISP3 protein
  • CT36 protein
  • GAPDL5 protein
  • Tpx-1 protein
  • TPX1 protein
  • TSP1 protein

Protein level used designations for CRISP2

cysteine-rich secretory protein 2 , cysteine rich secretory protein , cysteine-rich secretory protein 3 , cystein-rich secretory protein 2 , cysteine-rich secretory protein-2 , testis specific gene 1 , testis-specific protein TPX-1 , cysteine-rich secretory protein 2-like , testis specific protein 1 , cancer/testis antigen 36 , glyceraldehyde-3-phosphate dehydrogenase-like 5 , testis specific protein 1 (probe H4-1 p3-1) , cysteine-rich secretory protein-3 , cysteine-rich secretory protein 1 , autoantigen 1

GENE ID SPECIES
398591 Xenopus laevis
422045 Gallus gallus
462756 Pan troglodytes
706747 Macaca mulatta
100034138 Equus caballus
100462690 Ovis aries
22024 Mus musculus
360445 Rattus norvegicus
7180 Homo sapiens
474932 Canis lupus familiaris
397369 Sus scrofa
512443 Bos taurus
100135505 Cavia porcellus
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