anti-Cytokeratin 1 (KRT1) Antibodies

The protein encoded by KRT1 is a member of the keratin gene family. Additionally we are shipping KRT1 Kits (37) and KRT1 Proteins (11) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
KRT1 3848 P04264
KRT1 16678 P04104
KRT1 300250 Q6IMF3
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Top anti-KRT1 Antibodies at

Showing 10 out of 203 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Delivery Price Details
Human Rabbit Un-conjugated IHC (p), WB Anti- Cytokeratin 1 Picoband antibody, IHC(P) IHC(P): Human Oesophagus Squama Cancer Tissue Anti- Cytokeratin 1 Picoband antibody, IHC(P) IHC(P): Mouse Lung Tissue 100 μg 4 to 6 Days
Dog Rabbit Un-conjugated IHC, WB Rabbit Anti-KRT1 Antibody  arp42278 Paraffin Embedded Tissue: Human Skin Antibody Concentration: 1.25-2.5 ug/ml 100 μL 2 to 3 Days
Mouse Guinea Pig Un-conjugated IHC (fro), IHC (p), WB   0.1 mL 6 to 8 Days
Human Rabbit Un-conjugated FACS, IHC (p), WB KRT1 Antibody (Center) flow cytometric analysis of MCF-7 cells (bottom histogram) compared to a negative control cell (top histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. KRT1 Antibody (Center) IHC analysis in formalin fixed and paraffin embedded skin tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the KRT1 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated. 0.4 mL 6 to 8 Days
Human Rabbit Un-conjugated ICC, IHC, WB Figure. Western Blot; Sample: Lane1: Human A375 Cells; Lane2: Human H460 Cells; Lane3: Human Hela Cells; Lane4: Mouse Pancreas Tissue. 100 μg 15 to 18 Days
Mouse Rabbit Un-conjugated ICC, IHC, WB Figure.DAB staining on IHC-P. Samples: Mouse Tissue 100 μg 15 to 18 Days
Rat Rabbit Un-conjugated ICC, IHC, WB Western Blot; Sample: Rat Serum; Primary Ab: 1µg/ml Rabbit Anti-Rat KRT1 Antibody Second Ab: 0.2µg/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody (Catalog: SAA544Rb19) 100 μg 13 to 16 Days
Human Rabbit Un-conjugated ELISA, WB 100 μL Available
Human Rabbit Un-conjugated IHC, IHC (p), WB Human Skin: Formalin-Fixed, Paraffin-Embedded (FFPE) Anti-KRT1 / Cytokeratin 1 antibody IHC of human skin. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 2.5 ug/ml. This image was taken for the unconjugated form of this pro ... 100 μL 11 to 14 Days
Human Mouse Un-conjugated ELISA, IF/ICC, IHC, WB 100 μL 11 to 16 Days

Top referenced anti-KRT1 Antibodies

  1. Chicken Monoclonal KRT1 Primary Antibody for FACS, ICC - ABIN4302150 : Alibardi, Maurizii, Taddei: Immunocytochemical and electrophoretic distribution of cytokeratins in the resting stage epidermis of the lizard Podarcis sicula. in The Journal of experimental zoology 2001 (PubMed)
    Show all 15 Pubmed References

  2. Human Monoclonal KRT1 Primary Antibody for ICC, IHC (fro) - ABIN251201 : Boelsma, Gibbs, Faller, Ponec: Characterization and comparison of reconstructed skin models: morphological and immunohistochemical evaluation. in Acta dermato-venereologica 2000 (PubMed)
    Show all 11 Pubmed References

  3. Human Monoclonal KRT1 Primary Antibody for CyTOF, FACS - ABIN4302136 : McGowan, McCoy: Regulation of fibroblast lipid storage and myofibroblast phenotypes during alveolar septation in mice. in American journal of physiology. Lung cellular and molecular physiology 2014 (PubMed)
    Show all 5 Pubmed References

  4. Human Polyclonal KRT1 Primary Antibody for IHC (p), WB - ABIN3043868 : Wu, Yang, Zhou, Zhang, Bai, Lin, Ng, Dai, Chen, Chen: Effect of interleukin-1β and lipoxin A4 in human endometriotic stromal cells: Proteomic analysis. in The journal of obstetrics and gynaecology research 2016 (PubMed)
    Show all 4 Pubmed References

  5. Mouse (Murine) Polyclonal KRT1 Primary Antibody for IHC (fro), IHC (p) - ABIN126062 : Boehnke, Mirancea, Pavesio, Fusenig, Boukamp, Stark: Effects of fibroblasts and microenvironment on epidermal regeneration and tissue function in long-term skin equivalents. in European journal of cell biology 2007 (PubMed)
    Show all 5 Pubmed References

  6. Cat (Feline) Monoclonal KRT1 Primary Antibody for ICC, IHC (fro) - ABIN267554 : Meeker, Bragg, Poulton, Hudson: Transmigration of macrophages across the choroid plexus epithelium in response to the feline immunodeficiency virus. in Cell and tissue research 2012 (PubMed)
    Show all 4 Pubmed References

  7. Cow (Bovine) Polyclonal KRT1 Primary Antibody for IHC (fro), IHC (p) - ABIN153466 : Cuzi?, Bosnar, Kramari?, Ferenci?, Markovi?, Glojnari?, Erakovi? Haber: Claudin-3 and Clara cell 10 kDa protein as early signals of cigarette smoke-induced epithelial injury along alveolar ducts. in Toxicologic pathology 2012 (PubMed)
    Show all 4 Pubmed References

  8. Chicken Monoclonal KRT1 Primary Antibody for CyTOF, FACS - ABIN4302156 : Oppel, Tao, Shi, Ross, Zimmerman, He, Tong, Aster, Look: Loss of atrx cooperates with p53-deficiency to promote the development of sarcomas and other malignancies. in PLoS genetics 2019 (PubMed)
    Show all 3 Pubmed References

  9. Human Polyclonal KRT1 Primary Antibody for IHC, IHC (p) - ABIN4302278 : Gallotta, Gancitano, Pietrocola, Mora, Pezzicoli, Tuscano, Chiarot, Nardi-Dei, Taddei, Rindi, Speziale, Soriani, Grandi, Margarit, Bensi: SpyAD, a moonlighting protein of group A Streptococcus contributing to bacterial division and host cell adhesion. in Infection and immunity 2014 (PubMed)
    Show all 2 Pubmed References

More Antibodies against KRT1 Interaction Partners

Human Cytokeratin 1 (KRT1) interaction partners

  1. A colon score derived from serum CEA, CA19-9, CK1 and MUC1 is a potential valuable non-invasive index that could be used for detection and screening early stage colon cancer patients

  2. PAWS1 interacts and co-localises with the alpha isoform of casein kinase 1 (CK1), and that PAWS1 mutations incapable of binding CK1 fail both to activate Wnt signalling and to elicit axis duplication in Xenopus embryos.

  3. Results showed identical expression pattern for KRT1 and KRT10, their expression was higher in pediatric cases than in adults, especially in pediatric recurrent samples.

  4. The authors report a large Italian family affected Palmoplantar Keratoderma and Charcot Marie Tooth disease. Two different mutated genes, KRT1 and MPZ were responsible for the two main clinical signs. Exome analysis detected two missense mutations, one in KRT1 and one in MPZ.

  5. Results show that missense mutations exert dominant negative effects on the keratins K1/K10 protein structure by altering inter-chain interactions.

  6. KRT1 and the specific polymorphism of KRT1 in this Chinese Han population are associated with autoimmune diseases SLE and SSc

  7. Case Report: post-zygotic mosaicism of KRT/1o mutations in epidermolytic Ichthyosis.

  8. KRT1 played an important role of maintaining epithelial barrier and its down-regulation in intestinal tissue was correlated with the progression of inflammatory bowel disease.

  9. Report genetic/clinical spectrum of KRT1 mutations in keratinopathic ichthyosis.

  10. demonstrated the presence of a genetic cutaneous mosaicism. Both patients carry the KRT1 pI479T substitution, but in the palmoplantar areas of one of them, only the mutated allele is expressed (hemizygous). This leads to highlight a new type of cutaneous mosaic, the palmoplantar mosaicism

  11. In our study, the missense mutation in the proband and his mother with epidermolytic ichthyosis was a single amino acid difference in codon 478, which causes more serious skin manifestations

  12. Complete structure of an epithelial keratin 1/keratin 10 dimer has been presented.

  13. These findings indicate that exogenous FABP4 interacts with plasma membrane proteins, specifically CK1.

  14. analysis of a heterozygous novel splice junction mutation in the 2B domain of KRT1 in a family with diffuse palmoplantar keratoderma

  15. In ichthyosis with confetti, a causal de novo KRT1 mutation had a C-terminal frameshift, replacing 22 C-terminal AAs with an alternate 30-AA peptide. It distorted the IF network and mislocalized to the nucleus. Reversion occurred by mitotic recombination.

  16. In HeLa cells transiently expressing C2GnT-M-GFP, knockdown of KRT1 does not affect Golgi morphology but leaves C2GnT-M outside of the Golgi, resulting in the formation of sialyl-T antigen.

  17. Decreased levels of cytokeratin-1 is associated with breast cancer.

  18. Hsp74, a potential bladder cancer marker, has direct interaction with keratin 1.

  19. identified among endothelial antigens to which antibodies are produced during heart transplant rejection

  20. Case Report/Letter: specific mutation in 2B domain of KRT1 gives rise to mild phenotype of epidermolytic hyperkeratosis mimicking ichthyosis bullosa of Siemens.

Mouse (Murine) Cytokeratin 1 (KRT1) interaction partners

  1. SCF improves diabetic wound healing in part by increasing the recruitment of a unique stem cell population present in the skin.

  2. Absence of Krt1 caused a prenatal increase in interleukin-18 (IL-18) and the S100A8 and S100A9 proteins, accompanied by a barrier defect and perinatal lethality.

  3. The Krt1(-/-);Krt10(-/-) mice showed premature loss of nuclei during epidermal differentiation and lower levels of emerin, lamin A/C and Sun1, revealing a previously unknown function for IFs in maintaining nuclear integrity in the upper epidermis.

KRT1 Antigen Profile

Protein Summary

The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in the spinous and granular layers of the epidermis with family member KRT10 and mutations in these genes have been associated with bullous congenital ichthyosiform erythroderma. The type II cytokeratins are clustered in a region of chromosome 12q12-q13.

Gene names and symbols associated with anti-Cytokeratin 1 (KRT1) Antibodies

  • keratin 1 (KRT1) antibody
  • keratin 1 (Krt1) antibody
  • CK-1 antibody
  • CK1 antibody
  • EHK antibody
  • EHK1 antibody
  • EPPK antibody
  • K1 antibody
  • Kb1 antibody
  • KER1 antibody
  • Keratin-1 antibody
  • Krt-2.1 antibody
  • KRT1 antibody
  • KRT1A antibody
  • Krt2-1 antibody
  • Krt86 antibody
  • NEPPK antibody

Protein level used designations for anti-Cytokeratin 1 (KRT1) Antibodies

67 kDa cytokeratin , CK-1 , cytokeratin 1 , cytokeratin-1 , epidermolytic hyperkeratosis 1 , hair alpha protein , keratin, type II cytoskeletal 1 , type-II keratin Kb1 , K1 , keratin 86 , keratin complex 2, basic, gene 1 , keratin-1 , keratin 1 , cytokeratin VI (human cytokeratin 10) , cytokeratin Ia (human cytokeratin 1, epidermolytic hyperkeratosis) , type II keratin Kb1 , epithelial keratin 1 , epithelial keratin-1 , keratin 1 (epidermolytic hyperkeratosis) , Cytokeratin-1 , Keratin, type II cytoskeletal 1

3848 Homo sapiens
16678 Mus musculus
281266 Bos taurus
300250 Rattus norvegicus
444857 Canis lupus familiaris
100049664 Sus scrofa
738375 Pan troglodytes
100353415 Oryctolagus cuniculus
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