DNA (Cytosine-5-)-Methyltransferase 3 alpha (DNMT3A) ELISA Kits

CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Additionally we are shipping DNMT3A Antibodies (292) and DNMT3A Proteins (7) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
DNMT3A 1788 Q9Y6K1
Anti-Mouse DNMT3A DNMT3A 13435 O88508
DNMT3A 444984 Q1LZ53
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Top DNMT3A ELISA Kits at antibodies-online.com

Showing 2 out of 12 products:

Catalog No. Reactivity Sensitivity Range Images Quantity Supplier Delivery Price Details
Human 0.061 ng/mL 0.15 ng/mL - 10 ng/mL 96 Tests Log in to see 13 to 16 Days
$736.84
Details
Rat 0.094 ng/mL 0.156-10 ng/mL Typical standard curve 96 Tests Log in to see 12 to 14 Days
$638.00
Details

More ELISA Kits for DNMT3A Interaction Partners

Pig (Porcine) DNA (Cytosine-5-)-Methyltransferase 3 alpha (DNMT3A) interaction partners

  1. Data show that the expression levels of the 5 epigenetic modifying genes Dnmt1, Dnmt3a, Hdac1, Kdm3a and Uhrf1 were higher in group pig in highland (TH) than in group Yorkshire in highland (YH).

Cow (Bovine) DNA (Cytosine-5-)-Methyltransferase 3 alpha (DNMT3A) interaction partners

  1. The effect of p53 (show TP53 ELISA Kits) expression on the development of cloned embryos, and its interaction with HDAC1 (show HDAC1 ELISA Kits) and DNMT3A are reported.

  2. The expression levels of DNMT3a and DNMT3b (show DNMT3B ELISA Kits) were associated with several beef quality traits.

Horse (Equine) DNA (Cytosine-5-)-Methyltransferase 3 alpha (DNMT3A) interaction partners

  1. Among 18 genotypes analyzed, we were unable to record any significant differences in 5-methyl-2'-deoxycytidine levels, which suggested that age-related changes in global DNA methylation content are rather a function of time, and not a genetic component.

Human DNA (Cytosine-5-)-Methyltransferase 3 alpha (DNMT3A) interaction partners

  1. Together findings presented here recognize an inherent role of MTA1 (show MTA1 ELISA Kits) as a modifier of DNMT3a and IGFBP3 (show IGFBP3 ELISA Kits) expression, and consequently, the role of MTA1 (show MTA1 ELISA Kits)-DNMT3a-IGFBP3 (show IGFBP3 ELISA Kits) axis in breast cancer progression.

  2. we developed a modular dCas9-SunTag (dC9Sun-D3A) system that can recruit multiple DNMT3A catalytic domains to a target site for editing DNA methylation. dC9Sun-D3A is tunable, specific, and exhibits much higher induction of DNA methylation at target sites than the dC9-D3A direct fusion protein.

  3. Results indicate that DNMT3A mutations alone do not affect the clinical outcomes of AML (show RUNX1 ELISA Kits) patients undergoing allogeneic HSCT, but when accompanied by FLT3 (show FLT3 ELISA Kits)-ITD mutations, the OS was significantly reduced (5-year OS 0% for DNMT3A R882mut/FLT3 (show FLT3 ELISA Kits)-ITDpos patients vs. 62% DNMT3A R882wt/FLT3 (show FLT3 ELISA Kits)-ITDneg, p=0.025) and the relapse rate increased.

  4. Findings suggested that tumor overexpression of DNMT1 (show DNMT1 ELISA Kits) and DNMT3A is associated with tumor aggressive behavior and high-methylation status in pituitary adenomas. Data support a possible role of DNMT1 (show DNMT1 ELISA Kits) and DNMT3A in TSG (show TWSG1 ELISA Kits) promoter methylation leading to pituitary adenoma invasion.

  5. Genetic variation in DNMT3A gene is not associated with gastric cancer.

  6. concluded that miR (show MLXIP ELISA Kits)-876-5p suppressed hepatocellular carcinoma progression by targeting DNMT3A

  7. These findings indicated a novel mechanism by which EID3, a p300 (show EP300 ELISA Kits) acetyltransferase inhibitor, could directly affect DNMT3A, this enzyme possesses dual methylation and demethylation abilities.

  8. DNMT3A R882 mutation plays an important role in CN-AML (show RUNX1 ELISA Kits) patients' prognosis and clinical outcomes in the presence and absence of NPM1 (show NPM1 ELISA Kits) and FLT3 (show FLT3 ELISA Kits) mutations.

  9. a feedback loop between miR (show MLXIP ELISA Kits)-145 and DNMT3A is a potent signature for the Warburg effect in ovarian cancer, promising a potential target for improved anticancer treatment.

  10. In univariable analysis, patients carrying mutations in DNMT3A, U2AF1, and EZH2 (show EZH2 ELISA Kits) had worse overall and relapse-free survival.

Mouse (Murine) DNA (Cytosine-5-)-Methyltransferase 3 alpha (DNMT3A) interaction partners

  1. Dnmt3a appears to regulate satellite cell differentiation via DNA methylation. This mechanism may play a role in the decreased regeneration capacity during atrophy such as in aged sarcopenia.

  2. DNMT3A and TET1 regulate the epigenome and gene expression at specific targets via their functional interplay.

  3. individual pain vulnerability may be inherent mostly in the emotional/affective component of chronic pain and remain consistent in different aspects of negative emotion, in which adaptive changes in the function of DNA methyltransferase 3a for DNA methylation in central amygdala may play an important role.

  4. Taken together, these data demonstrate that adipose Dnmt3a is a novel epigenetic mediator of insulin (show INS ELISA Kits) resistance in vitro and in vivo.

  5. The aim of the present study is to investigate spatial and temporal expression levels and subcellular localizations of the DNMT1 (show DNMT1 ELISA Kits), DNMT3A, and DNMT3B (show DNMT3B ELISA Kits) proteins in the mouse germinal vesicle (GV) and metaphase II (MII) oocytes, and early embryos from 1-cell to blastocyst stages.

  6. our Dnmt3a R878H mice have shown that leukemic cells have altered gene expression and epigenetic regulatory patterns contributing to the growth/survival advantage over WT mice.The present study found that the DNMT3A mutation contributed to hypomethylation in the gene body region of mTOR (show FRAP1 ELISA Kits) in Dnmt3aR878H/WT mice.

  7. Knockdown of DNMT3A or DNMT1 protected neurons against mutant Htt-induced toxicity, together demonstrating a requirement for DNMTs in mutant Htt-triggered neuronal death and suggesting a neurodegenerative mechanism based on DNA methylation-mediated transcriptional repression.

  8. Data demonstrate that DNMT3A and DNA methylation are key modulators of mast cell responsiveness to acute and chronic stimulation.

  9. These data suggest that DNMT3a is required for nerve injury-induced and MBD1 (show DPEP1 ELISA Kits)-mediated epigenetic silencing of the MOR (show OPRM1 ELISA Kits) and KOR (show OPRK1 ELISA Kits) in the injured DRG. DNMT3a inhibition may serve as a promising adjuvant therapy for opioid use in neuropathic pain management.

  10. Data show that conditional deletion of Dnmt3a and simultaneous "knock in" of Flt3ITD/+, cooperate to drive leukemia development at a faster rate than Dnmt3a loss alone.

DNMT3A Antigen Profile

Antigen Summary

CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a DNA methyltransferase that is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes to the cytoplasm and nucleus and its expression is developmentally regulated. Alternative splicing results in multiple transcript variants encoding different isoforms.

Gene names and symbols associated with DNMT3A

  • DNA methyltransferase 3 alpha (DNMT3A) antibody
  • DNA methyltransferase 3A (Dnmt3a) antibody
  • DNA methyltransferase 3 alpha (Dnmt3a) antibody
  • DNA methyltransferase 3 alpha (dnmt3a) antibody
  • DNA (cytosine-5-)-methyltransferase 3 alpha b (dnmt3ab) antibody
  • DNMT3A antibody
  • dnmt3a1 antibody
  • DNMT3A2 antibody
  • dnmt6 antibody
  • M.HsaIIIA antibody
  • MmuIIIA antibody

Protein level used designations for DNMT3A

DNA (cytosine-5)-methyltransferase 3A , DNA cytosine methyltransferase 3 alpha , DNA (cytosine-5-)-methyltransferase 3 alpha , DNA MTase HsaIIIA , DNA cytosine methyltransferase 3A2 , DNA methyltransferase 3A , DNA methyl transferase alpha , DNA-methyltransferase 3a , DNA MTase MmuIIIA , DNA methyltransferase MmuIIIA , LOW QUALITY PROTEIN: DNA (cytosine-5)-methyltransferase 3A , DNA (cytosine-5-)-methyltransferase 6

GENE ID SPECIES
100037301 Sus scrofa
359716 Bos taurus
739139 Pan troglodytes
694822 Macaca mulatta
100055881 Equus caballus
482996 Canis lupus familiaris
1788 Homo sapiens
421991 Gallus gallus
100030681 Monodelphis domestica
100344715 Oryctolagus cuniculus
100500776 Ovis aries
100510798 Felis catus
100594618 Nomascus leucogenys
13435 Mus musculus
444984 Rattus norvegicus
100529107 Anolis carolinensis
100721625 Cavia porcellus
553189 Danio rerio
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