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anti-CDT2/RAMP Antibodies

42 results:

anti-CDT2/RAMP antibody (Denticleless E3 Ubiquitin Protein Ligase Homolog) (C-Term) Primary Antibody

DTL Reactivity: Human, Mouse FACS, IF, IP, WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2451940
$500.00
Plus shipping costs $45.00
100 μL
local_shipping Shipping to: United States
Delivery in 9 to 11 Business Days

anti-CDT2/RAMP antibody (Denticleless E3 Ubiquitin Protein Ligase Homolog) (AA 229-256) Primary Antibody

DTL Reactivity: Human, Mouse EIA, FACS, WB Host: Rabbit Polyclonal unconjugated
Pubmed 1
Catalog No. ABIN951451
$629.20
Plus shipping costs $45.00
0.4 mL
local_shipping Shipping to: United States
Available

anti-CDT2/RAMP antibody (Denticleless E3 Ubiquitin Protein Ligase Homolog) Primary Antibody

DTL Reactivity: Human, Mouse, Rat WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN630978
$672.32
Plus shipping costs $45.00
50 μg
local_shipping Shipping to: United States
Delivery in 9 to 11 Business Days

anti-CDT2/RAMP antibody (Denticleless E3 Ubiquitin Protein Ligase Homolog) (AA 1-730) Primary Antibody

DTL Reactivity: Human IF, WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN949333
$585.71
Plus shipping costs $45.00
100 μg
local_shipping Shipping to: United States
Delivery in 11 to 12 Business Days

anti-CDT2/RAMP antibody (Denticleless E3 Ubiquitin Protein Ligase Homolog) Primary Antibody

DTL Reactivity: Human, Mouse ELISA, WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6390479
$367.82
Plus shipping costs $45.00
100 μL (More quantities available)
local_shipping Shipping to: United States
Delivery in 11 to 13 Business Days

anti-CDT2/RAMP antibody (Denticleless E3 Ubiquitin Protein Ligase Homolog) (N-Term) Primary Antibody

DTL Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2782560
$389.00
Plus shipping costs $45.00
100 μL (More quantities available)
local_shipping Shipping to: United States
Delivery in 2 to 3 Business Days

anti-CDT2/RAMP antibody (Denticleless E3 Ubiquitin Protein Ligase Homolog) (AA 229-256) Primary Antibody

DTL Reactivity: Human, Mouse FACS, WB Host: Rabbit Polyclonal RB24420 unconjugated
Catalog No. ABIN654926
$412.50
Plus shipping costs $45.00
400 μL (More quantities available)
local_shipping Shipping to: United States
Delivery in 10 to 11 Business Days

anti-CDT2/RAMP antibody (Denticleless E3 Ubiquitin Protein Ligase Homolog) (AA 182-231) Primary Antibody

DTL Reactivity: Human, Mouse, Rat, Bat, Cow, Dog, Guinea Pig, Horse, Monkey, Pig, Rabbit WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6738232
$653.03
Plus shipping costs $45.00
100 μL
local_shipping Shipping to: United States
Delivery in 11 to 14 Business Days

anti-CDT2/RAMP antibody (Denticleless E3 Ubiquitin Protein Ligase Homolog) (N-Term) Primary Antibody

DTL Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2442043
$318.55
Plus shipping costs $45.00
100 μL
local_shipping Shipping to: United States
Delivery in 2 to 3 Business Days

anti-CDT2/RAMP antibody (Denticleless E3 Ubiquitin Protein Ligase Homolog) (AA 181-280) Primary Antibody

DTL Reactivity: Human ELISA, IF (cc), IF (p), IHC (fro), IHC (p), WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN873173
$339.90
Plus shipping costs $45.00
100 μL
local_shipping Shipping to: United States
Delivery in 4 to 6 Business Days
  • Type Primary
    • Primary
  • Target Denticleless E3 Ubiquitin Protein Ligase Homolog (DTL)
    • Denticleless E3 Ubiquitin Protein Ligase Homolog (DTL)
    • Histone 3 (H3)
    • Epidermal Growth Factor Receptor (EGFR)
    • Tumor Protein P53 (TP53)
    • Mast/stem Cell Growth Factor Receptor (KIT)
    • Protein tyrosine Phosphatase, Receptor Type, C (PTPRC)
    • tau Protein
    • CD4
    • Receptor tyrosine-protein kinase erbB-2 (ErbB2/Her2)
    • Tumor Necrosis Factor alpha (TNF alpha)
    • V-Akt Murine Thymoma Viral Oncogene Homolog 1 (AKT1)
    • Interferon gamma (IFNG)
    • Estrogen Receptor 1 (ESR1)
    • Nuclear Factor-kB p65 (NFkBP65)
    • BCL2-Associated Agonist of Cell Death (BAD)
    • V-Raf-1 Murine Leukemia Viral Oncogene Homolog 1 (RAF1)
    • Albumin (ALB)
    • B-Cell CLL/lymphoma 2 (BCL2)
    • Tuberous Sclerosis 2 (TSC2)
    • CD8a Molecule (CD8A)
    • CD19 Molecule (CD19)
    • Platelet/endothelial Cell Adhesion Molecule (PECAM1)
    • Hemagglutinin (HA)
    • CD3 epsilon (CD3E)
    • Jun Proto-Oncogene (JUN)
    • Integrin alpha M (ITGAM)
    • Myc Proto-Oncogene protein (MYC)
    • CD44
    • Histone H4
    • Interleukin 6 (IL6)
    • Interleukin 2 Receptor, alpha (IL2RA)
    • Ribosomal Protein S6 Kinase, 70kDa, Polypeptide 1 (RPS6KB1)
    • CD8
    • Vimentin (VIM)
    • C-Abl Oncogene 1, Non-Receptor tyrosine Kinase (ABL1)
    • Interleukin 2 (IL2)
    • VEGF Receptor 2 (VEGFR2)
    • Tuberous Sclerosis 1 (TSC1)
    • CD5
    • Insulin Receptor Substrate 1 (IRS1)
    • Amyloid beta (A4) Precursor Protein (APP)
    • Glial Fibrillary Acidic Protein (GFAP)
    • CD14
    • CD34
    • Epithelial Cell Adhesion Molecule (EPCAM)
    • Mucin 1 (MUC1)
    • CD3
    • PTK2 Protein tyrosine Kinase 2 (PTK2)
    • Catenin, beta (CATNB)
    • Membrane-Spanning 4-Domains, Subfamily A, Member 1 (MS4A1)
    • Synuclein, alpha (SNCA)
  • Application
    • Western Blotting (WB)
    • ELISA
    • Flow Cytometry (FACS)
    • Immunohistochemistry (IHC)
    • Immunofluorescence (IF)
    • Immunoprecipitation (IP)
    • Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    • Enzyme Immunoassay (EIA)
    • Immunofluorescence (Cultured Cells) (IF (cc))
    • Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    • Immunohistochemistry (Frozen Sections) (IHC (fro))
  • Reactivity
    • Human
    • Mouse
    • Rat
    • Cow
    • Dog
    • Guinea Pig
    • Horse
    • Rabbit
    • Bat
    • Monkey
    • Pig
  • Cited in publications
  • Images available
  • Preservative free only
  • Host
    • Rabbit
    • Chicken
  • Clonality
    • Polyclonal
  • Clone
    • RB24420
  • Binding Specificity
    • AA 229-256
    • Center
    • Internal Region
    • AA 393-550
    • AA 1-730
    • C-Term
    • N-Term
    • AA 1-196
    • AA 181-280
    • AA 182-231
    • AA 375-425
    • AA 680-730
    • Middle Region
  • Conjugate
    • Un-conjugated
    • Biotin
    • FITC
    • HRP
    • APC
    • Alkaline Phosphatase (AP)
    • PE
    • Alexa Fluor 488
    • Alexa Fluor 555
    • Alexa Fluor 594
    • Alexa Fluor 647
    • Alexa Fluor 680
    • Alexa Fluor 750
  • Isotype
    • IgG
    • Ig Fraction
  • Format
    • Liquid
    • Lyophilized

CDT2/RAMP (DTL) Antigen Profile

Protein Summary

Substrate-specific adapter of a DCX (DDB1-CUL4-X-box) E3 ubiquitin-protein ligase complex required for cell cycle control, DNA damage response and translesion DNA synthesis. The DCX(DTL) complex, also named CRL4(CDT2) complex, mediates the polyubiquitination and subsequent degradation of CDT1 and CDKN1A/p21(CIP1). CDT1 degradation in response to DNA damage is necessary to ensure proper cell cycle regulation of DNA replication. CDKN1A/p21(CIP1) degradation during S phase or following UV irradiation is essential to control replication licensing. Most substrates require their interaction with PCNA for PIP-box, and those containing the 'K+4' motif in the PIP box, recruit the DCX(DTL) complex, leading to their degradation. In undamaged proliferating cells, the DCX(DTL) complex also promotes the 'Lys-164' monoubiquitination of PCNA, thereby being involved in PCNA-dependent translesion DNA synthesis (By similarity).

Gene names and symbols associated with DTL

  • denticleless E3 ubiquitin protein ligase homolog (DTL) antibody
  • denticleless E3 ubiquitin protein ligase (Dtl) antibody
  • denticleless E3 ubiquitin protein ligase homolog (Dtl) antibody
  • denticleless E3 ubiquitin protein ligase homolog S homeolog (dtl.S) antibody
  • denticleless E3 ubiquitin protein ligase homolog (Drosophila) (dtl) antibody
  • 2810047L02Rik antibody
  • 5730564G15Rik antibody
  • cb151 antibody
  • cdt2 antibody
  • cdt2-a antibody
  • chunp6871 antibody
  • dcaf2 antibody
  • l2dtl antibody
  • ramp antibody
  • RGD1310439 antibody
  • wu:fb54b02 antibody

Protein level used designations for DTL

DDB1 and CUL4 associated factor 2 , DDB1- and CUL4-associated factor 2 , RA regulated nuclear matrix associated protein , RA-regulated nuclear matrix-associated protein , denticleless homolog , denticleless protein homolog , lethal(2) denticleless protein homolog , retinoic acid-regulated nuclear matrix-associated protein , Meth A ramp , meth A retinoic acid-regulated nuclear matrix-associated protein , retinoic-acid regulated nuclear matrix-associated protein , denticleless protein homolog A

GENE ID SPECIES
51514 Homo sapiens
76843 Mus musculus
305073 Rattus norvegicus
490279 Canis lupus familiaris
421373 Gallus gallus
735103 Xenopus laevis
539953 Bos taurus
100723475 Cavia porcellus
192314 Danio rerio

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