CDT2/RAMP antibody (C-Term)

Catalog No. ABIN7448536

This Rabbit Polyclonal antibody specifically detects CDT2/RAMP in IHC. It exhibits reactivity toward Human and Mouse.

Quick Overview for CDT2/RAMP antibody (C-Term) (ABIN7448536)

Target: CDT2/RAMP (DTL) (Denticleless E3 Ubiquitin Protein Ligase Homolog (DTL))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CDT2/RAMP antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Product Details anti-CDT2/RAMP Antibody

Binding Specificity: C-Term

Purpose: Rabbit anti-DTL/CDT2 IHC Antibody, Affinity Purified

Predicted Reactivity: Orangutan,Monkey,Gorilla,Chimpanzee,Northern white-cheeked gibbon,Crab-eating macaque

Purification: Affinity Purified

Immunogen: Between AA 680 and C-term

Isotype: IgG

Application Details

Application Notes: 1:100 - 1:500

Restrictions: For Research Use only

Handling

Concentration: 200 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for CDT2/RAMP

Target: CDT2/RAMP (DTL) (Denticleless E3 Ubiquitin Protein Ligase Homolog (DTL))

Alternative Name: DTL/CDT2

Background: Background: DTL/CDT2 is a component of the CUL4A-DDB1 E3 ubiquitinating complex and plays a role in downregulating CDT1, an essential component of pre-replication complexes (Pre-RC) that ensures the genome is replicated only once per cycle. As part of the CUL4A-DDB1 E3 ligase complex DTL/CDT2 is also involved in the regulation of other proteins involved in the G2/M cell cycle checkpoint.

Gene ID: 51514

NCBI Accession: NP_057532

UniProt: Q9NZJ0