Dishevelled, Dsh Homolog 3 (Drosophila) Proteins (DVL3)

DVL3 is a member of a multi-gene family which shares strong similarity with the Drosophila dishevelled gene, dsh. Additionally we are shipping DVL3 Antibodies (85) and and many more products for this protein.

list all proteins Gene Name GeneID UniProt
DVL3 13544 Q61062
DVL3 1857 Q92997
Rat DVL3 DVL3 303811  
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Top DVL3 Proteins at

Showing 4 out of 6 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 60 Days
Insect Cells Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 60 Days
Escherichia coli (E. coli) Human His tag,GST tag 100 μg Log in to see 15 to 18 Days
Wheat germ Human GST tag 10 μg Log in to see 11 to 12 Days

DVL3 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)

Human , ,
, ,

More Proteins for Dishevelled, Dsh Homolog 3 (Drosophila) (DVL3) Interaction Partners

Xenopus laevis Dishevelled, Dsh Homolog 3 (Drosophila) (DVL3) interaction partners

  1. Different Dvl (show DVL2 Proteins) proteins (Dvl1 (show DVL1 Proteins), Dvl2 (show DVL2 Proteins), Dvl3) and the composition of dishevelled (show DVL2 Proteins)-beta-arrestin protein complexes contribute to the specific activation of individual branches of Wnt (show WNT2 Proteins) signaling in Xenopus gastrulation.

  2. Data show that maternal Dvl2 and 3 are required for convergence extension movements downstream of the dorsally localized signaling pathway activated by Xnr3, but not downstream of the pathway activated by activin.

Mouse (Murine) Dishevelled, Dsh Homolog 3 (Drosophila) (DVL3) interaction partners

  1. Dvl-2 (show DVL2 Proteins) and Dvl-3 have a widespread distribution in both the olfactory epithelium and olfactory bulb

  2. Dvl3 is important for IPMK (show IPMK Proteins) to access substrates and generate IP5, activating down-stream signaling.

  3. Dishevelled (show DVL2 Proteins)-KSRP (show KHSRP Proteins) complex operates in Wnt (show WNT2 Proteins) regulation of beta-catenin (show CTNNB1 Proteins), functioning post-transcriptionally upon CTNNB1 (show CTNNB1 Proteins) mRNA stability.

  4. Dvl2 (show DVL2 Proteins) and Dvl3 proteins were found to be localized to the apical side of the node cells, and their location was polarized to the posterior side of the cells before the posterior positioning of the basal body.

  5. As embryos reach blastocyst stage, Dishevelled 2 (show DVL2 Proteins) becomes increasingly associated with cell membrane in trophectoderm cells, while at E4.5, Dishevelled 3 is highly enriched in the cytoplasm of inner cell mass cells.

  6. The expression of Dishevelleds in mammalian cells provide an estimate of the relative cellular abundance of each Dvl (show DVL1 Proteins).

  7. G alpha o (show GNAO1 Proteins) mediates WNT (show WNT2 Proteins)-JNK (show MAPK8 Proteins) signaling through dishevelled 1 (show DVL1 Proteins) and 3, RhoA (show RHOA Proteins) family members, and MEKK 1 (show MAP2K1 Proteins) and 4 in mammalian cells

  8. Dvl1 (show DVL1 Proteins), Dvl2 (show DVL2 Proteins) and Dvl3 are functionally redundant in cardiac outflow tract, cochlea, and neural tube development.

Human Dishevelled, Dsh Homolog 3 (Drosophila) (DVL3) interaction partners

  1. Dvl3 is overexpressed in human HCCs (show HCCS Proteins). The NP-Dvl3 is the more stable and active form of the protein and enhances HCC (show FAM126A Proteins) stemness.

  2. we found that Wnt3a (show WNT3A Proteins) treatment rapidly induces hyperphosphorylation and stabilization of Dvl2 (show DVL2 Proteins) and Dvl3. Our findings suggest a model of positive regulation of PKCzeta (show PRKCZ Proteins)-mediated Dvl (show DVL2 Proteins) signaling activity, to produce a strong and sustained response to Wnt3a (show WNT3A Proteins) treatment by stabilizing Dvl (show DVL2 Proteins) protein levels.

  3. Studied and identified candidate biomarkers of biochemical recurrence (BCR (show BCR Proteins)) of prostate adenocarcinoma by integrating reverse-phase protein array (RPPA) and mRNA datafrom The Cancer Genome Atlas (TCGA). Found DVL3 was expressed in patients with a higher risk of BCR (show BCR Proteins). DVL3 may be a novel and easily applicable recurrence predictor of localised prostate adenocarcinoma.

  4. two mutually exclusive functions of the DEP domain in Wnt (show WNT2 Proteins) signal transduction - binding to Frizzled to recruit Dishevelled (show DVL2 Proteins) to the receptor complex, is reported.

  5. Genetic changes between MLH1 (show MLH1 Proteins) and MSH2 were significantly positively correlated (p = 0.032). We also noted a positive correlation between genetic changes of MSH2 and DVL3 genes (p = 0.034).

  6. Data show that dishevelled (show DVL2 Proteins) proteins DVL1 (show DVL1 Proteins), 2 and 3 were exclusively expressed in chronic lymphatic leukaemia (CLL) cells as compared to normal peripheral blood mononuclear cells (PBMCs).

  7. Kif26b, together with Dvl3/Daam1 (show DAAM1 Proteins), initiates cell polarity through the control of planar cell polarity-signaling pathway-dependent activation in endothelial cells.

  8. DVL3 transcripts decreased in individuals with major depressive disorder

  9. we demonstrate that normally ALFY attenuates the canonical Wnt (show WNT2 Proteins) signaling pathway via autophagy-dependent removal specifically of aggregates of DVL3 and not of Dvl1 (show DVL1 Proteins) or Dvl2 (show DVL2 Proteins).

  10. All variants in DVL3 result in a -1 frameshift, indicating that these highly specific alterations might be a common cause of dominant Robinow syndrome.

DVL3 Protein Profile

Protein Summary

This gene is a member of a multi-gene family which shares strong similarity with the Drosophila dishevelled gene, dsh. The Drosophila dishevelled gene encodes a cytoplasmic phosphoprotein that regulates cell proliferation.

Gene names and symbols associated with DVL3

  • dishevelled segment polarity protein 3 L homeolog (dvl3.L)
  • dishevelled segment polarity protein 3 (dvl3)
  • dishevelled segment polarity protein 3 (DVL3)
  • dishevelled segment polarity protein 3 (Dvl3)
  • dishevelled segment polarity protein 3a (dvl3a)
  • dsh3 protein
  • dvl3 protein
  • wu:fb75f04 protein
  • wu:fi22h02 protein
  • wu:fp61b09 protein

Protein level used designations for DVL3

DSH homolog 3 , Dishevelled-3 , dishevelled, dsh homolog 3 , dishevelled3 , segment polarity protein dishevelled homolog DVL-3 , dishevelled, dsh homolog 3 (Drosophila) , dishevelled-3 , dishevelled 3 (homologous to Drosophila dsh) , dishevelled 3, dsh homolog , dishevelled 3 , dishevelled, dsh homolog 3a

444527 Xenopus laevis
100144702 Xenopus (Silurana) tropicalis
460882 Pan troglodytes
100220188 Taeniopygia guttata
100583216 Nomascus leucogenys
13544 Mus musculus
1857 Homo sapiens
539203 Bos taurus
303811 Rattus norvegicus
424949 Gallus gallus
478650 Canis lupus familiaris
100621038 Sus scrofa
80972 Danio rerio
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