anti-Distal-Less Homeobox 5 (DLX5) Antibodies

DLX5 encodes a member of a homeobox transcription factor gene family similiar to the Drosophila distal-less gene. Additionally we are shipping Distal-Less Homeobox 5 Kits (15) and Distal-Less Homeobox 5 Proteins (8) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
DLX5 1749 P56178
DLX5 13395 P70396
DLX5 25431 P50575
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Top anti-Distal-Less Homeobox 5 Antibodies at antibodies-online.com

Showing 10 out of 108 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated IHC, WB Immunohistochemistry with Thymus tissue at an antibody concentration of 5µg/ml using anti-DLX5 antibody (ARP31607_P050) WB Suggested Anti-DLX5 Antibody Titration:  0.2-1 ug/ml  ELISA Titer:  1:312500  Positive Control:  THP-1 cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Cow Rabbit Un-conjugated IHC, WB Human Lung WB Suggested Anti-DLX5 Antibody Titration:  0.2-1 ug/ml  Positive Control:  Transfected 293T 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Goat Un-conjugated ELISA, IHC, WB EB09284 (1µg/ml) staining of Human Bone Marrow lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 100 μg Log in to see 6 to 7 Days
$358.02
Details
Cow Rabbit Un-conjugated IHC, WB WB Suggested Anti-DLX5 Antibody Titration:  1.25ug/ml  ELISA Titer:  1:312500  Positive Control:  Human Placenta Host:  Mouse  Target Name:  DLX5  Sample Tissue:  Mouse Skeletal Muscle  Antibody Dilution:  1ug/ml 100 μL Log in to see 2 to 3 Days
$229.00
Details
Human Rabbit Un-conjugated IHC (p), WB Western blot analysis of DLX5 (arrow) using rabbit polyclonal DLX5 Antibody (Center) . 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the DLX5 gene. DLX5 Antibody (Center)  western blot analysis in HL-60 cell line lysates (35ug/lane).This demonstrates the DLX5 antibody detected the DLX5 protein (arrow). 400 μL Log in to see 10 to 11 Days
$335.50
Details
Cow Rabbit Un-conjugated IHC, WB Human Heart Human Liver 100 μL Log in to see 2 to 3 Days
$229.00
Details
Human Goat Un-conjugated ELISA, WB Immunohistochemistry-Paraffin: DLX5 Antibody  - (2.5ug/ml) staining of paraffin embedded Human Placenta. Steamed antigen retrieval with citrate buffer pH 6, AP-staining. 0.1 mg Log in to see 7 to 9 Days
$485.88
Details
Chicken Rabbit Un-conjugated IC, IF, IP, IHC, WB Immunofluorescent analysis of DLX5 staining in Raw264.7 cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 °C in a humidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark. DAPI was used to stain the cell nuclei (blue). Immunohistochemical analysis of DLX5 staining in human lung cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. 200 μL Log in to see 13 to 14 Days
$487.50
Details
Human Rabbit Un-conjugated ICC, IF, IHC, IHC (p), WB Western Blot: Dlx5 Antibody [NBP1-85793] - Lane 1: Marker [kDa] 220, 112, 84, 47, 32, 26, 17.Lane 2: Human cell line RT-4.Lane 3: Human cell line U-251MG sp Immunohistochemistry-Paraffin: Dlx5 Antibody [NBP1-85793] - Staining of human rectum shows strong nuclear and moderate cytoplasmic positivity in glandular cells. 0.1 mL Log in to see 10 to 13 Days
$491.63
Details
Human Rabbit Un-conjugated IHC, ELISA, WB Western blot analysis of extracts from HeLa/293/COLO205 cells, using DLX5 Antibody. The lane on the right is treated with the synthesized peptide. Immunohistochemistry analysis of paraffin-embedded human lung carcinoma tissue, using DLX5 Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details

Top referenced anti-Distal-Less Homeobox 5 Antibodies

  1. Human Polyclonal DLX5 Primary Antibody for ELISA, WB - ABIN451750 : Lee, Kim, Kim, Park, Kang, Kyung, Sung, Wozney, Kim, Ryoo: BMP-2-induced Runx2 expression is mediated by Dlx5, and TGF-beta 1 opposes the BMP-2-induced osteoblast differentiation by suppression of Dlx5 expression. in The Journal of biological chemistry 2003 (PubMed)
    Show all 2 Pubmed References

  2. Human Polyclonal DLX5 Primary Antibody for ICC, IF - ABIN4305382 : Stadler, Rexhepaj, Singan, Murphy, Pepperkok, Uhlén, Simpson, Lundberg: Immunofluorescence and fluorescent-protein tagging show high correlation for protein localization in mammalian cells. in Nature methods 2013 (PubMed)

More Antibodies against Distal-Less Homeobox 5 Interaction Partners

Human Distal-Less Homeobox 5 (DLX5) interaction partners

  1. Our results in mice suggest that long-range DLX5 enhancer elements located in the human SLC25A13 (show slc25a13 Antibodies) gene may underlie the sensorineural hearing loss that is sometimes associated with SHFM1 (show SHFM1 Antibodies).

  2. These results indicate activation of DLX5 and RUNX2 (show RUNX2 Antibodies) via its distal promoter represents a unique feature of GFs, and is important for ECM (show MMRN1 Antibodies) regulation. Down-regulation of these transcription factors in PAFs could be associated with their property to degrade collagen, which may impact on the process of periodontitis.

  3. these findings indicate that, in MSCs, DLX5 is a master regulator of osteogenesis. Furthermore, tanshinone IIA may be valuable for stem cell-based therapies of certain bone diseases.

  4. As a result of disturbed imprinting, the upregulated DLX5 affects trophoblast proliferation in preeclampsia.

  5. These data indicate that certain missense mutations diminish the ability of the Dlx5 homeodomain to recognize and bind target DNAs, and they likely destabilize the formation of functional complexes.

  6. In cells grown on titanium support, DLX5 and RUNX1 (show RUNX1 Antibodies) were respectively upregulated (+3.12-fold) and downregulated (-2.14-fold)

  7. Absent expression of the osteoblast-specific maternally imprinted genes, DLX5 and DLX6, causes split hand/split foot malformation type I.

  8. Heterozygous DLX5 nonsense mutation c.G115T(p.E39X) associated with isolated split-hand/foot malformation with reduced penetrance and variable expressivity in two unrelated Polish families.

  9. A novel heterozygous mutation in exon 3 of DLX5 found in the family members with SHFM1 (show SHFM1 Antibodies) phenotype.

  10. Genome sequencing of the deletion breakpoints showed that the DLX5 and DLX6 genes are disomic but the putative DYNC1I1 (show DYNC1I1 Antibodies) exon 15 and 17 enhancers are deleted.

Mouse (Murine) Distal-Less Homeobox 5 (DLX5) interaction partners

  1. T-614 promotes osteoblastic differentiation by increasing the expression of Osterix (show SP7 Antibodies) and Dlx5.

  2. Results indicate that Dlx5 and Runx2 (show RUNX2 Antibodies) are critical factors for the upregulated Osterix (show SP7 Antibodies) expression in shPP2A cells, which is considered to be important for the accelerated osteoblast differentiation in these cells.

  3. FGF10 (show FGF10 Antibodies) pathway is downregulated in Dlx5(-/-) mice, and activation of FGF10 (show FGF10 Antibodies) signaling rescues cranial neural crest cell proliferation and myogenic differentiation.

  4. High DLX5 expression is associated with T-cell lymphomagenesis.

  5. Both transient and stable expression of Necdin (show NDN Antibodies) induced osteoblast-specific markers in an osteogenic cell line through formation of a complex with distal-less Homeobox 5 (Dlx5) and Runx2 (show RUNX2 Antibodies) promoter activation.

  6. DLX5 and DLX6 reciprocally inhibit BMP/H2-mediated H1 enhancer regulation in mandible embryonic development.

  7. We found that in Dlx5;6 DKO limbs, the AER expresses lower levels of Wnt5a (show WNT5A Antibodies), shows scattered beta-catenin (show CTNNB1 Antibodies) responsive cells and altered basolateral and planar cell polarity (PCP (show BMP1 Antibodies)).

  8. Dlx5 and Dlx6 expression determines uterine architecture and adenogenesis and is needed for implantation

  9. The results presented here indicate that loss of Dlx5 causes a down-modulation of miR (show MLXIP Antibodies)-9 and of miR (show MLXIP Antibodies)-200-class, which results in the over-expression of the Foxg1 (show FOXG1 Antibodies) protein.

  10. Lck (show LCK Antibodies)-Dlx5 mice develop T-ALLs that consistently acquire overexpression of Myc (show MYC Antibodies) and activation of Akt (show AKT1 Antibodies).

Xenopus laevis Distal-Less Homeobox 5 (DLX5) interaction partners

  1. Retinoic acid treatment leads to a progressive loss of Dlx5 and Dlx6 expression in the first pharyngeal arch.

Pig (Porcine) Distal-Less Homeobox 5 (DLX5) interaction partners

  1. Imprinting analysis shows that DLX5 is maternally expressed in some organs and tissues but not imprinted in others.

Zebrafish Distal-Less Homeobox 5 (DLX5) interaction partners

  1. Data indicate that retinoic acid (RA) induces the expression patterns of genes normally expressed in the posterior tooth-forming region, such as pitx2 (show PITX2 Antibodies) and dlx2b.

Distal-Less Homeobox 5 (DLX5) Antigen Profile

Protein Summary

This gene encodes a member of a homeobox transcription factor gene family similiar to the Drosophila distal-less gene. The encoded protein may play a role in bone development and fracture healing. Mutation in this gene, which is located in a tail-to-tail configuration with another member of the family on the long arm of chromosome 7, may be associated with split-hand/split-foot malformation.

Gene names and symbols associated with DLX5

  • distal-less homeobox 5 (DLX5) antibody
  • distal-less homeobox 5 (Dlx5) antibody
  • distal-less homeobox 5 L homeolog (dlx5.L) antibody
  • distal-less homeobox 5 (dlx5) antibody
  • distal-less homeobox 2b (dlx2b) antibody
  • AI385752 antibody
  • dll3 antibody
  • dlx5 antibody
  • MGC69418 antibody
  • RDLX antibody
  • SHFM1D antibody
  • X-dll3 antibody

Protein level used designations for DLX5

distal-less homeo box 5 , homeobox protein DLX-5 , split hand/foot malformation type 1 with sensorineural hearing loss , DLX-3 , homeobox protein DLX-3 , cDlx , XDLL-3 , homeobox protein DLL-3 , putative transcription factor DLL3 , distal-less homeobox 5 , distal-less homeobox protein 5 , DLX-5 , distal-less homeobox gene 5 , distal-less homeobox protein 2b , homeobox protein Dlx2b

GENE ID SPECIES
1749 Homo sapiens
13395 Mus musculus
25431 Rattus norvegicus
373969 Gallus gallus
399265 Xenopus laevis
447997 Xenopus (Silurana) tropicalis
463554 Pan troglodytes
482313 Canis lupus familiaris
507415 Bos taurus
697853 Macaca mulatta
100008630 Oryctolagus cuniculus
100286863 Sus scrofa
30557 Danio rerio
101119298 Ovis aries
100736137 Cavia porcellus
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