anti-DUOXA1 Antibodies
Dual oxidases DUOX1 and DUOX2 are NADPH oxidases which are involved in hydrogen peroxide production necessary for thyroid hormonogenesis.
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10 results:
anti-DUOXA1 antibody (Dual Oxidase Maturation Factor 1) (C-Term) Primary Antibody
anti-DUOXA1 antibody (Dual Oxidase Maturation Factor 1) (AA 1-298) Primary Antibody
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anti-DUOXA1 antibody (Dual Oxidase Maturation Factor 1) (C-Term) Primary Antibody
anti-DUOXA1 antibody (Dual Oxidase Maturation Factor 1) (AA 297-346) Primary Antibody
anti-DUOXA1 antibody (Dual Oxidase Maturation Factor 1) Primary Antibody
anti-DUOXA1 antibody (Dual Oxidase Maturation Factor 1) (AA 73-183) Primary Antibody
anti-DUOXA1 antibody (Dual Oxidase Maturation Factor 1) (AA 73-183) (Biotin) Primary Antibody
anti-DUOXA1 antibody (Dual Oxidase Maturation Factor 1) (AA 73-183) (HRP) Primary Antibody
anti-DUOXA1 antibody (Dual Oxidase Maturation Factor 1) (AA 73-183) (FITC) Primary Antibody
anti-DUOXA1 antibody (Dual Oxidase Maturation Factor 1) (AA 1-299) Primary Antibody
DUOXA1 Antigen Profile
Protein Summary
Dual oxidases DUOX1 and DUOX2 are NADPH oxidases which are involved in hydrogen peroxide production necessary for thyroid hormonogenesis. They form a heterodimer with specific maturation factors DUOXA1 and DUOXA2, respectively, which is essential for the maturation and function of the DUOX enzyme complexes. This gene encodes the DUOX1 activator or maturation factor DUOXA1. Rat studies identified a bidirectional promoter which controls the transcription of the DUOX1 and DUOXA1 genes. This protein is cotransported to the cell surface when coexpressed with DUOX1 and is retained in the endoplasmic reticulum when expressed without DUOX1 protein. The expression of this gene or the DUOX1 gene is not suppressed by thyroglobulin (Tg), a macromolecular precursor in thyroid hormone synthesis, while the expression of the DUOX2 and DUOXA2 are significantly suppressed by the Tg. This protein is also a p53-regulated neurogenic factor involved in p53 dependent neuronal differentiation. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Gene names and symbols associated with DUOXA1
- dual oxidase maturation factor 2 (DUOXA2) antibody
- dual oxidase maturation factor 1 (DUOXA1) antibody
- dual oxidase maturation factor 1 (LOC100405759) antibody
- dual oxidase maturation factor 1 (Duoxa1) antibody
- BC019755 antibody
- mol antibody
- Nip antibody
- Nip1 antibody
- NUMBIP antibody
- RGD1306601 antibody
Protein level used designations for DUOXA1
dual oxidase maturation factor 1 , Numb-interacting protein , dual oxidase activator 1 , dual oxidase maturation factor 1 alpha , dual oxidase maturation factor 1 beta , dual oxidase maturation factor 1 delta , dual oxidase maturation factor 1 gamma , homolog of Drosophila Numb-interacting protein , Numb-interacting protein 1
| GENE ID | SPECIES |
|---|---|
| 427484 | Gallus gallus |
| 487536 | Canis lupus familiaris |
| 530151 | Bos taurus |
| 713058 | Macaca mulatta |
| 100405759 | Callithrix jacchus |
| 100446897 | Pongo abelii |
| 100596084 | Nomascus leucogenys |
| 90527 | Homo sapiens |
| 213696 | Mus musculus |
| 311374 | Rattus norvegicus |
| 100653516 | Sus scrofa |
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