anti-DUOXA1 Antibodies

Dual oxidases DUOX1 and DUOX2 are NADPH oxidases which are involved in hydrogen peroxide production necessary for thyroid hormonogenesis.

Data Quality
  • 1
  • 4
Type
  • 11
    Primary
Antigen
  • 11
Reactivity
  • 11
  • 2
  • 2
  • 1
  • 1
Application
  • 7
  • 5
  • 1
  • 1
  • 1
Host
  • 9
  • 2
Clonality
  • 11
Binding Specificity
  • 4
  • 2
  • 1
  • 1
  • 1
Conjugate
  • 8
  • 1
  • 1
  • 1
Isotype
  • 6
Format
  • 8
  • 2
11 Products
ReactivityHuman
Application WB
Order details Cat. No. ABIN926689
$517.86
50 μg
Plus shipping costs $45.00
Delivery in 9 to 11 Business Days
ReactivityHuman
Application WB
Order details Cat. No. ABIN530004
$440.00
50 μg
Plus shipping costs $45.00
Delivery in 11 to 12 Business Days
ReactivityCow (Bovine), Dog (Canine), Human, Pig (Porcine)
Application WB
Order details Cat. No. ABIN2788717
$229.00
100 μL
Plus shipping costs $45.00
Delivery in 2 to 3 Business Days
ReactivityDog (Canine), Human, Pig (Porcine)
Application WB
Order details Cat. No. ABIN6747594
$551.83
100 μL
Plus shipping costs $45.00
Delivery in 11 to 14 Business Days
ReactivityHuman, Mouse (Murine), Rat (Rattus)
Application IF (p), IHC (p), WB
Order details Cat. No. ABIN1387935
$327.80
100 μL
Plus shipping costs $45.00
Delivery in 3 to 7 Business Days
ReactivityHuman
Application ELISA, WB
Order details Cat. No. ABIN5026038
$436.16
100 μg
Plus shipping costs $45.00
Delivery in 11 to 16 Business Days
ReactivityHuman
Application ELISA, IF/ICC
Order details Cat. No. ABIN6057594
$464.30
Plus shipping costs $45.00
Delivery in 11 to 16 Business Days
ReactivityHuman
Application ELISA
Order details Cat. No. ABIN6086348
$464.30
Plus shipping costs $45.00
Delivery in 11 to 16 Business Days
ReactivityHuman
Application ELISA
Order details Cat. No. ABIN6086350
$464.30
Plus shipping costs $45.00
Delivery in 11 to 16 Business Days
ReactivityHuman
Application ELISA
Order details Cat. No. ABIN6086352
$464.30
Plus shipping costs $45.00
Delivery in 11 to 16 Business Days
ReactivityHuman
Application WB
Order details Cat. No. ABIN2256086
$625.43
50 μg
Plus shipping costs $45.00
Delivery in 11 to 16 Business Days
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DUOXA1 Antigen Profile

Protein Summary

Dual oxidases DUOX1 and DUOX2 are NADPH oxidases which are involved in hydrogen peroxide production necessary for thyroid hormonogenesis. They form a heterodimer with specific maturation factors DUOXA1 and DUOXA2, respectively, which is essential for the maturation and function of the DUOX enzyme complexes. This gene encodes the DUOX1 activator or maturation factor DUOXA1. Rat studies identified a bidirectional promoter which controls the transcription of the DUOX1 and DUOXA1 genes. This protein is cotransported to the cell surface when coexpressed with DUOX1 and is retained in the endoplasmic reticulum when expressed without DUOX1 protein. The expression of this gene or the DUOX1 gene is not suppressed by thyroglobulin (Tg), a macromolecular precursor in thyroid hormone synthesis, while the expression of the DUOX2 and DUOXA2 are significantly suppressed by the Tg. This protein is also a p53-regulated neurogenic factor involved in p53 dependent neuronal differentiation. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with DUOXA1

  • dual oxidase maturation factor 2 (DUOXA2) antibody
  • dual oxidase maturation factor 1 (DUOXA1) antibody
  • dual oxidase maturation factor 1 (LOC100405759) antibody
  • dual oxidase maturation factor 1 (Duoxa1) antibody
  • BC019755 antibody
  • mol antibody
  • Nip antibody
  • Nip1 antibody
  • NUMBIP antibody
  • RGD1306601 antibody

Protein level used designations for DUOXA1

dual oxidase maturation factor 1 , Numb-interacting protein , dual oxidase activator 1 , dual oxidase maturation factor 1 alpha , dual oxidase maturation factor 1 beta , dual oxidase maturation factor 1 delta , dual oxidase maturation factor 1 gamma , homolog of Drosophila Numb-interacting protein , Numb-interacting protein 1

GENE ID SPECIES
427484 Gallus gallus
487536 Canis lupus familiaris
530151 Bos taurus
713058 Macaca mulatta
100405759 Callithrix jacchus
100446897 Pongo abelii
100596084 Nomascus leucogenys
90527 Homo sapiens
213696 Mus musculus
311374 Rattus norvegicus
100653516 Sus scrofa