Dynein, Light Chain, Roadblock Type 1 Proteins (DYNLRB1)

DYNLRB1 is a member of the roadblock dynein light chain family and encodes a cytoplasmic protein that is capable of binding intermediate chain proteins. Additionally we are shipping DYNLRB1 Antibodies (13) and and many more products for this protein.

list all proteins Gene Name GeneID UniProt
DYNLRB1 67068 P62627
DYNLRB1 170714 P62628
DYNLRB1 83658 Q9NP97
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Top DYNLRB1 Proteins at antibodies-online.com

Showing 9 out of 10 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 30 to 35 Days
$5,465.26
Details
Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 30 to 35 Days
$5,465.26
Details
HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Log in to see Available
$814.00
Details
Wheat germ Human GST tag 10 μg Log in to see 11 to 12 Days
$414.29
Details
Escherichia coli (E. coli) Human His tag 50 μg Log in to see 15 to 19 Days
$400.00
Details
Yeast Rat His tag   1 mg Log in to see 60 to 71 Days
$2,159.67
Details
Yeast Cow His tag   1 mg Log in to see 60 to 71 Days
$2,159.67
Details
Escherichia coli (E. coli) Human His tag   1 mg Log in to see 2 to 3 Days
$5,723.08
Details
Human Un-conjugated   1 mg Log in to see 6 Days
$7,816.29
Details

DYNLRB1 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)

Rat (Rattus)

Human , ,
, ,

More Proteins for Dynein, Light Chain, Roadblock Type 1 (DYNLRB1) Interaction Partners

Mouse (Murine) Dynein, Light Chain, Roadblock Type 1 (DYNLRB1) interaction partners

  1. The presence of an N-terminal tag on dynein light-chain Roadblock/LC7 affects its interaction with a functional partner.

Human Dynein, Light Chain, Roadblock Type 1 (DYNLRB1) interaction partners

  1. Human colorectal carcinoma cells display decreased tumor progression and invasion when a novel anti-cell motility target, DYNLRB1, is being silenced.

  2. TGFbeta (show TGFB1 Proteins) regulates km23-1 interaction with the R1beta regulatory subunit of protein kinase A.

  3. these findings demonstrate that km23-1 regulates RhoA (show RHOA Proteins) and motility-associated actin modulating proteins, suggesting that km23-1 may represent a novel target for anti-metastatic therapy.

  4. km23-1 is required for TGFbeta1 (show TGFB1 Proteins) autoinduction through Smad2 (show SMAD2 Proteins)-independent Ras/ERK (show EPHB2 Proteins)/JNK (show MAPK8 Proteins) pathways

  5. Silencing of km23, either through somatic genetic mutation or promoter hypermethylation, is rare in ovarian, breast, and colorectal cancers.

  6. report the 2.1-A crystal structure of Dnlc2A using single anomalous diffraction

  7. DYNLRB1 specifically interacts with all three Rab6 isoforms and co-localises at the Golgi.

  8. Identification of dynein light chain road block-1 as a novel interaction partner with the human reduced folate carrier.

  9. Findings indicate that km23-2 (DYNLRB2 (show DYNLRB2 Proteins)) is required for Smad3 (show SMAD3 Proteins)-dependent TGFbeta (show TGFB1 Proteins) signaling. Km23-2 has functions in TGFbeta (show TGFB1 Proteins) signaling that are distinct from those for km23-1 (DYNLRB1).

DYNLRB1 Protein Profile

Protein Summary

This gene is a member of the roadblock dynein light chain family and encodes a cytoplasmic protein that is capable of binding intermediate chain proteins. Upregulation of this gene has been associated with hepatocellular carcinomas, suggesting that this gene may be involved in tumor progression.

Gene names and symbols associated with DYNLRB1

  • dynein light chain roadblock-type 1 (Dynlrb1)
  • dynein light chain roadblock-type 1 (DYNLRB1)
  • 2010012N15Rik protein
  • 2010320M17Rik protein
  • 9430076K19Rik protein
  • AV124457 protein
  • BITH protein
  • BLP protein
  • DNCL2A protein
  • DNLC2A protein
  • km23 protein
  • km23-1 protein
  • ROBLD1 protein

Protein level used designations for DYNLRB1

dynein light chain 2A, cytoplasmic , dynein, cytoplasmic, light chain 2A , dynein, cytoplasmic, light polypeptide 2A , BLP , bithoraxoid-like protein , dynein-associated protein Km23 , dynein-associated protein RKM23 , robl/LC7-like protein , ROBL/LC7-like 1 , dynein light chain roadblock-type 1 , roadblock domain-containing protein 1

GENE ID SPECIES
67068 Mus musculus
170714 Rattus norvegicus
83658 Homo sapiens
513342 Bos taurus
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