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Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Additionally we are shipping Dynein, Light Chain, Roadblock Type 2 Antibodies (23) and many more products for this protein.
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study found that murine leukemia virus (MLV) associates functionally and specifically with the dynein light chain DYNLRB2, which is required for infection; study provides more insight into the molecular requirements for retrograde transport of the MLV preintegration complex and demonstrates a role for DYNLRB2 in viral infection
Among the total 68 liver cancer samples tested, DNLC2B was down-regulated in 28 cases.
Findings indicate that km23 (show DYNLRB1 Proteins)-2 (DYNLRB2) is required for Smad3 (show SMAD3 Proteins)-dependent TGFbeta (show TGFB1 Proteins) signaling. Km23 (show DYNLRB1 Proteins)-2 has functions in TGFbeta (show TGFB1 Proteins) signaling that are distinct from those for km23 (show DYNLRB1 Proteins)-1 (DYNLRB1 (show DYNLRB1 Proteins)).
Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules (By similarity).
dynein light chain 2B, cytoplasmic
, dynein, cytoplasmic, light chain 2B
, dynein, cytoplasmic, light polypeptide 2B
, bithoraxoid-like protein
, dynein light chain roadblock-type 2
, roadblock domain containing 2
, roadblock domain-containing protein 2