Endoglin (ENG) ELISA Kits

ENG encodes a homodimeric transmembrane protein which is a major glycoprotein of the vascular endothelium. Additionally we are shipping Endoglin Antibodies (764) and Endoglin Proteins (53) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
ENG 2022 P17813
ENG 13805 Q63961
ENG 497010  
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Top Endoglin ELISA Kits at antibodies-online.com

Showing 7 out of 74 products:

Catalog No. Reactivity Sensitivity Range Images Quantity Supplier Delivery Price Details
Human 0.047 ng/mL 0.156-10 ng/mL 96 Tests Log in to see 13 to 16 Days
$611.11
Details
Mouse 12.9 pg/mL 31.2 pg/mL - 2000 pg/mL 96 Tests Log in to see 13 to 16 Days
$418.95
Details
Rat 0.35 ng/mL 0.78 ng/mL - 50 ng/mL 96 Tests Log in to see 13 to 16 Days
$720.00
Details
Dog 0.3 ng/mL 0.78 ng/mL - 50 ng/mL 96 Tests Log in to see 13 to 16 Days
$757.89
Details
Pig 0.094 ng/mL 0.156-10 ng/mL   96 Tests Log in to see 12 to 14 Days
$715.00
Details
Rabbit 1.875 ng/mL 3.125-200 ng/mL   96 Tests Log in to see 12 to 14 Days
$715.00
Details
Monkey 0.094 ng/mL 0.156-10 ng/mL   96 Tests Log in to see 12 to 14 Days
$715.00
Details

Top referenced Endoglin ELISA Kits

  1. Human ENG ELISA Kit for Sandwich ELISA - ABIN624967 : Levy, Finestone: Renal response to four hours of biliary obstruction in the dog. in The American journal of physiology 1983 (PubMed)
    Show all 4 Pubmed References

  2. Human ENG ELISA Kit for Sandwich ELISA - ABIN414754 : Silva, Teixeira, Oliveira, Almeida, Almeida, Águas, Vasconcelos: Endothelial Dysfunction and Nailfold Videocapillaroscopy Pattern as Predictors of Digital Ulcers in Systemic Sclerosis: a Cohort Study and Review of the Literature. in Clinical reviews in allergy & immunology 2015 (PubMed)
    Show all 4 Pubmed References

  3. Human ENG ELISA Kit for Sandwich ELISA - ABIN2684119 : Grisanti, Canbek, Kaiserling, Adam, Lafaut, Gelisken, Szurman, Henke-Fahle, Oficjalska-Mlynczak, Bartz-Schmidt: Expression of endoglin in choroidal neovascularization. in Experimental eye research 2004 (PubMed)
    Show all 3 Pubmed References

  4. Rat (Rattus) ENG ELISA Kit for Sandwich ELISA - ABIN1884529 : Matloub, Salama, Aglan, AbouSamra, ElSouda, Ahmed: Exploiting bilosomes for delivering bioactive polysaccharide isolated from Enteromorpha intestinalis for hacking hepatocellular carcinoma. in Drug development and industrial pharmacy 2018 (PubMed)

More ELISA Kits for Endoglin Interaction Partners

Human Endoglin (ENG) interaction partners

  1. Plasma level of soluble endoglin is increased in type 2 diabetic patients with diabetic nephropathy.

  2. Study describes a novel mutation in exon 9 of ENG (c.1145G>A) found in five affected members of a family, all of them with characteristic symptoms of hereditary hemorrhagic telangiectasia. This mutation involves Cys382 residue of the Endoglin protein (p.Cys382>Tyr) in the zona pellucida module of its extracellular region.

  3. This review summarizes the current data concerning the role and signalling pathways of endoglin in hepatocellular carcinoma development and progression, and provides an overview of the strategies available for a specific targeting of CD105 in anti-angiogenic therapy in Hepatocellular carcinoma.

  4. Increased sEng and sVCAM-1 and decreased free VEGF plasma levels were found in women with severe preeclampsia, compared with normotensive pregnant group.

  5. circulating soluble Eng can influence vascular development and arteriovenous malformations by modulating angiogenesis.

  6. Data indicate an articulated expression of endoglin/CD105 in acute leukemia, suggesting a therapeutic potential of anti-CD105 monoclonal antibody.

  7. Here we report the genetic characterization and functional analysis of the heterozygous mutation c.-142A>T in the 5'UTR region of ENG found in a family with several members affected by Hereditary hemorrhagic telangiectasia ..Transfection studies in monkey cells using endoglin expression vectors demonstrated that c-142A>T mutation results in a clear reduction in the levels of the endoglin protein.

  8. CD105(+) fibroblasts were found to circumscribe epithelia with neuroendocrine differentiation. CAF-derived SFRP1, driven by CD105 signaling, was necessary and sufficient to induce prostate cancer neuroendocrine differentiation in a paracrine manner.

  9. Combining radiation and CD105 targeting to address the DNA repair.

  10. No correlation was identified between the tumor CD105 (endoglin) expression and survival in CSCC patients treated with radical RT +/- chemotherapy.

  11. Recombinant short-endoglin overexpression reduces unilateral ureteral obstruction-induced renal fibrosis. As long endoglin overexpression provokes renal fibrosis we conclude that endoglin-mediated induction of renal fibrosis in this model is dependent on its cytoplasmic domain.

  12. endoglin promoted VEGF-induced tip cell formation. Mechanistically, endoglin interacted with VEGF receptor (VEGFR)-2 in a VEGF-dependent manner, which sustained VEGFR2 on the cell surface and prevented its degradation. Endoglin mutants deficient in the ability to interact with VEGFR2 failed to sustain VEGFR2 on the cell surface and to promote VEGF-induced tip cell formation.

  13. Endoglin isoforms are differentially upregulated in liver samples of patients with chronic and acute liver injury.

  14. Ki67 LI, CD105, and alpha-SMA expression showed significant differences between normal, low-risk oral epithelial dysplasia and high-risk oral epithelial dysplasia. These findings further support that features such as increased basal cell layer hyperplasia, abnormal superficial mitosis, increased nuclear-cytoplasmic ratio, and hyperchromasia could be transformation-relevant dysplastic features.

  15. Spindle-shaped gastric cancer stromal cells expressing CD73, CD90 or CD105 are involved in disease progression, and among them, CD105-positive cells are strongly associated with poor prognosis.

  16. New results furthermore revealed how Eng affects endothelial cell migration and cell shape control in response to these forces, thereby providing new avenues for our understanding of arteriovenous malformations cause.

  17. The ratio of sFlt-1/sEGFR could be used as a novel candidate biochemical marker in monitoring the severity of preterm preeclampsia. sEndoglin and sEGFR may be involved in the pathogenesis of small for gestational age in preterm preelampsia.

  18. Increased cord blood soluble endoglin is associated with the development of severe or moderate bronchopulmonary dysplasia in preterm infants with maternal preeclampsia.

  19. ENG, ACVRL1, and SMAD4 mutations result in different phenotypes in hereditary hemorrhagic telangiectasia

  20. High expression of CD105 is associated with Oral Invasive Carcinomas.

Mouse (Murine) Endoglin (ENG) interaction partners

  1. These data reveal a novel function of CD105 in beige adipocytes: maintaining their thermogenic program by regulating Smad2 signaling.

  2. circulating soluble Eng can influence vascular development and arteriovenous malformations by modulating angiogenesis.

  3. endoglin promoted VEGF-induced tip cell formation. Mechanistically, endoglin interacted with VEGF receptor (VEGFR)-2 in a VEGF-dependent manner, which sustained VEGFR2 on the cell surface and prevented its degradation. Endoglin mutants deficient in the ability to interact with VEGFR2 failed to sustain VEGFR2 on the cell surface and to promote VEGF-induced tip cell formation.

  4. Endoglin deficiency in hepatic stellate cell significantly aggravates fibrosis in response to injury in two different murine models of liver fibrosis and increases alpha-SMA and fibronectin expression in vitro.

  5. Transplantation of mesenchymal stem cells, when combined with endothelial progenitor cells, accelerate muscle recovery in a mouse model of hind limb ischemia, through an endoglin-dependent mechanism.

  6. we cannot rule out a possibility that a long-term chronic exposure (9 months and more) to soluble endoglin alone or combined with other cardiovascular risk factors may contribute to alterations of heart function and structure in Sol-Eng+ mice, which is the topic in our lab in ongoing experiments

  7. Data show that concomitant activin receptor-like kinase 1 (Acvrl1) and endoglin (Eng) deficiency synergistically decreases pancreatic neuroendocrine tumor volume.

  8. Endoglin is necessary for the pro-angiogenic properties of the cardiosphere-derived cells secretome.

  9. systemic DPP4 inhibition restores the impaired mononuclear cell homing in Eng+/- animals post-myocardial infarction, and enhances cardiac repair, which might be explained by restoring the balance between the inflammatory and regenerative macrophages present in the heart

  10. results suggest that soluble endoglin modulates inflammatory-related diseases and open new perspectives leading to the development of novel and targeted approaches for the prevention and treatment of cardiovascular diseases

  11. Endoglin controls blood vessel diameter through endothelial cell shape changes in response to haemodynamic cues.

  12. Endoglin prevents vascular malformation by regulating flow-induced cell migration and specification through VEGFR2 signalling.

  13. Identification of novel regulators of developmental hematopoiesis using Endoglin regulatory elements as molecular probes

  14. Endoglin has an important role in VSMC recruitment and blood vessel maturation during angiogenesis.

  15. the TGFbeta1 coreceptor Eng selectively regulates expression of multiple transient receptor potential channels in the setting of left or right ventricular pressure overload

  16. Endothelial cell-specific endoglin expression in islets of Langerhans is sensitive to VEGF and plays partial roles in driving islet vascular development, however such regulation appears to be distinct to mechanisms required to modulate islet viability and size.

  17. Study provides evidence that the expression of endoglin is required for the establishment of uterine receptivity and the decidualization process, which mediate embryo adhesion or the attachment reaction.

  18. The changes in CD90 and CD105 expression in the testis and ovary of mice are reported.

  19. the altered immune activity of endoglin deficient macrophages could help to explain the higher rate of infectious diseases seen in HHT1 patients.

  20. These results demonstrate a requirement for endoglin in descendants of Pax3-expressing vascular cell precursors.

Endoglin (ENG) Antigen Profile

Antigen Summary

This gene encodes a homodimeric transmembrane protein which is a major glycoprotein of the vascular endothelium. This protein is a component of the transforming growth factor beta receptor complex and it binds TGFB1 and TGFB3 with high affinity. Mutations in this gene cause hereditary hemorrhagic telangiectasia, also known as Osler-Rendu-Weber syndrome 1, an autosomal dominant multisystemic vascular dysplasia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with Endoglin (ENG) ELISA Kits

  • endoglin (ENG) antibody
  • endoglin (Eng) antibody
  • AI528660 antibody
  • AI662476 antibody
  • CD105 antibody
  • DKFZp469D0419 antibody
  • END antibody
  • ENG antibody
  • HHT1 antibody
  • MGC137842 antibody
  • ORW1 antibody
  • S-endoglin antibody

Protein level used designations for Endoglin (ENG) ELISA Kits

endoglin (Osler-Rendu-Weber syndrome 1) , endoglin , endoglin-like , CD105 antigen , cell surface MJ7/18 antigen , transmembrane glycoprotein

GENE ID SPECIES
609166 Canis lupus familiaris
615844 Bos taurus
741046 Pan troglodytes
771557 Gallus gallus
100173392 Pongo abelii
100226246 Taeniopygia guttata
100357448 Oryctolagus cuniculus
100387791 Callithrix jacchus
397096 Sus scrofa
2022 Homo sapiens
13805 Mus musculus
497010 Rattus norvegicus
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