anti-Eukaryotic Translation Elongation Factor 1 alpha 2 (EEF1A2) Antibodies

EEF1A2 encodes an isoform of the alpha subunit of the elongation factor-1 complex, which is responsible for the enzymatic delivery of aminoacyl tRNAs to the ribosome. Additionally we are shipping EEF1A2 Proteins (8) and and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
EEF1A2 1917 Q05639
EEF1A2 13628 P62631
EEF1A2 24799 P62632
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Top anti-EEF1A2 Antibodies at antibodies-online.com

Showing 10 out of 80 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB Host:  Rabbit  Target Name:  EEF1A2  Sample Type:  Human Fetal Heart  Antibody Dilution:  1.0ug/ml WB Suggested Anti-EEF1A2 antibody Titration: 1 ug/mL Sample Type: Human HepG2 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated IHC (p), WB IHC-P Image EEF1A2 antibody detects EEF1A2 protein at cytosol on mouse fore brain by immunohistochemical analysis. Sample: Paraffin-embedded mouse fore brain. EEF1A2 antibody , dilution: 1:500. IHC-P Image EEF1A2 antibody detects EEF1A2 protein at cytosol on rat fore brain by immunohistochemical analysis. Sample: Paraffin-embedded rat fore brain. EEF1A2 antibody , dilution: 1:500. 100 μL Log in to see 1 to 2 Days
$358.60
Details
Human Rabbit Un-conjugated IHC (p), WB WB Image Sample(30μg whole cell lysate) A: 293T B: A431 , C: H1299 D: HeLa S3 , E: Hep G2 , F: MOLT4 , G: Raji , 10% SDS PAGE antibody diluted at 1:1000 WB Image Sample (50 ug of whole cell lysate) A: mouse brain 10% SDS PAGE antibody diluted at 1:5000 100 μL Log in to see 1 to 2 Days
$358.60
Details
Human Rabbit Un-conjugated IHC, IHC (p), WB Immunohistochemistry-Paraffin: EEF1A2 Antibody [NBP2-33280] - Liver cancer Immunohistochemistry: EEF1A2 Antibody [NBP2-33280] - Staining of human cerebellum shows strong cytoplasmic positivity in Purkinje cells. 0.1 mL Log in to see 10 to 13 Days
$491.63
Details
Mouse Rabbit Un-conjugated IHC (p), WB EEF1A2 Antibody (C-term) (ABIN656488) immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. 400 μL Log in to see 10 to 11 Days
$335.50
Details
Human Rabbit Un-conjugated IHC, IHC (p), WB Western Blot: EEF1A2 Antibody [NBP1-32555] - Sample (50 ug of whole cell lysate) A: mouse brain 10% SDS PAGE; antibody diluted at 1:5000. Western Blot: EEF1A2 Antibody [NBP1-32555] - Sample(30ug whole cell lysate)A: 293TB: A431 C: H1299D: HeLa S3 E: Hep G2 F: MOLT4 G: Raji 10% SDS PAGE, antibody diluted at 1:1000. 100 μL Log in to see 8 to 11 Days
$514.63
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB Formalin fixed and paraffin embedded human brain tissue reacted with EEF1A2 Antibody (C-term) followed by peroxidase conjugation of the secondary antibody and DAB staining. Western blot analysis of EEF1A2 Antibody (C-term) Cat.-No AP51369PU-N in mouse liver tissue lysates (35ug/lane).This demonstrates the EEF1A2 antibody detected the EEF1A2 protein (arrow). 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Mouse Un-conjugated ELISA, WB EEF1A2 polyclonal antibody (A01), Lot # 070201JCSb Western Blot analysis of EEF1A2 expression in Hela S3 NE . EEF1A2 polyclonal antibody (A01), Lot # 070201JCSb. Western Blot analysis of EEF1A2 expression in human thyroid(diffuse hyperplasia). 50 μL Log in to see 11 to 12 Days
$305.71
Details
Human Rabbit Un-conjugated IHC (p), WB Human Brain, cerebellum: Formalin-Fixed, Paraffin-Embedded (FFPE) Human Brain, cortex: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated IHC, IHC (p), WB Human Brain, cerebellum: Formalin-Fixed, Paraffin-Embedded (FFPE) Human Brain, cortex: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μL Log in to see 7 to 9 Days
$484.00
Details

EEF1A2 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-EEF1A2 Antibodies

  1. Human Polyclonal EEF1A2 Primary Antibody for ELISA, WB - ABIN560693 : Scaggiante, Dapas, Bonin, Grassi, Zennaro, Farra, Cristiano, Siracusano, Zanconati, Giansante, Grassi: Dissecting the expression of EEF1A1/2 genes in human prostate cancer cells: the potential of EEF1A2 as a hallmark for prostate transformation and progression. in British journal of cancer 2012 (PubMed)
    Show all 2 Pubmed References

  2. Human Polyclonal EEF1A2 Primary Antibody for IHC, IHC (p) - ABIN4307082 : Qiu, Huang, Chen, Li, Wu, Wu, Huang: Eukaryotic elongation factor-1α 2 knockdown inhibits hepatocarcinogenesis by suppressing PI3K/Akt/NF-κB signaling. in World journal of gastroenterology 2016 (PubMed)

More Antibodies against EEF1A2 Interaction Partners

Human Eukaryotic Translation Elongation Factor 1 alpha 2 (EEF1A2) interaction partners

  1. The overexpression of EEF1A2 is a frequent event in localized prostate cancer and is associated with histopathology features and a shorter biochemical recurrence-free survival. Due to its independence from serum PSA (show PLAG1 Antibodies) levels, EEF1A2 could serve as valuable biomarker in risk-stratification of localized prostate cancer

  2. We report a pair of siblings carrying a homozygous missense mutation p.P333L in EEF1A2 who exhibited global developmental delay, failure to thrive, dilated cardiomyopathy and epilepsy, ultimately leading to death in early childhood. EEF1A2 appears to be critical for normal heart function in humans, and its deficiency results in clinical abnormalities in neurologic function as well as in skeletal and cardiac muscle defects

  3. eEF1A2 is highly expressed in hepatocellular carcinoma. Its silencing significantly decreases HCC (show FAM126A Antibodies) tumorigenesis, likely by inhibiting PI3K (show PIK3CA Antibodies)/Akt (show AKT1 Antibodies)/NF-kappaB (show NFKB1 Antibodies) signaling.

  4. Differential gene expression analysis demonstrated significant upregulation of PDZK1IP1, EEF1A2 and RPL41 (ENSG00000279483) genes in the intrahepatic cholangiocarcinoma samples when compared with the matched paratumor samples.

  5. In both cases, a de novo recurrent heterozygous mutation in EEF1A2 [c.364G>A (p.E122K)] was identified by whole-exome sequencing. CONCLUSION: This report provides clinical data on epileptic encephalopathy in patients with EEF1A2 mutation. Continuous high-voltage delta activity seen over both parietal areas may be a unique manifestation of EEF1A2 mutation.

  6. Our results provide novel information on the intracellular distribution and interaction of eEF1A (show EEF1A1 Antibodies) isoforms.

  7. By directly targeting eEF1A2.

  8. Both eEF1A1 (show EEF1A1 Antibodies) and eEF1A2 colocalise with all eEF1B (show EEF1B2 Antibodies) subunits, in such close proximity that they are highly likely to be in a complex.

  9. De novo EEF1A2 mutations in patients with characteristic facial features, intellectual disability, autistic behaviors and epilepsy.

  10. Finally, a strong association between the expression of EEF1A2, phosphorylated AKT (show AKT1 Antibodies) and MDM4 (show MDM4 Antibodies) was observed in human HCC (show FAM126A Antibodies) samples. Strong activation of the EEF1A2/PI3K (show PIK3CA Antibodies)/AKT (show AKT1 Antibodies)/mTOR (show FRAP1 Antibodies)/MDM4 (show MDM4 Antibodies) signaling pathway was observed in HCC (show FAM126A Antibodies) patients

Mouse (Murine) Eukaryotic Translation Elongation Factor 1 alpha 2 (EEF1A2) interaction partners

  1. This provides the first in vivo confirmation that eEF1A2 plays an important role in translation.

  2. Heterozygous mutant mice showed no deficit in neuromuscular function or signs of spinal cord pathology, in spite of the low levels of eEF1A2

  3. In-depth analysis using site-directed mutagenesis revealed that PKCbetaI could phosphorylate Ser (show SIGLEC1 Antibodies)(3) of the eEF1A2 isoform and that the association between eEF1A2 and PKCbetaI was dependent on the phosphorylation status of eEF1A2

  4. EEF1A2 may play contribute to the induction or progression of some plasmacytomas and a small percentage of multiple myeloma.

  5. these results suggest an important role for eEF1A2 in driving cap-independent translation of utrophin (show UTRN Antibodies) A in skeletal muscle.

  6. expression of eEF1A-2/S1 protein is activated upon myogenic differentiation

  7. This is a putative oncogene (show RAB1A Antibodies) in ovarian cancer.

  8. Data suggest that spontaneous failure of eEF1A2 expression in the wasted mutant first triggers gliosis in spinal cord and retraction of motor nerve terminals in muscle, and then motor neuron pathology and death.

  9. eEF1A-2 interacts with Prdx-I to functionally provide cells with extraordinary resistance to oxidative stress-induced (show SQSTM1 Antibodies) cell death[eEF1A-2 and Prdx-I]

  10. The above findings suggest that an increase in free-form eEF1A under alkaline conditions plays a critical role in alkalinization-induced cell growth.

Rabbit Eukaryotic Translation Elongation Factor 1 alpha 2 (EEF1A2) interaction partners

  1. the interaction of eEF1A with two known partners - calmodulin and actin

  2. eEF1A2 crystals obtained using ammonium sulfate as precipitant diffracted to 2.5 A resolution and belonged to space group P6(1)22 or P6(3)22 (unit-cell parameters a = b = 135.4, c = 304.6 A).

EEF1A2 Antigen Profile

Protein Summary

This gene encodes an isoform of the alpha subunit of the elongation factor-1 complex, which is responsible for the enzymatic delivery of aminoacyl tRNAs to the ribosome. This isoform (alpha 2) is expressed in brain, heart and skeletal muscle, and the other isoform (alpha 1) is expressed in brain, placenta, lung, liver, kidney, and pancreas. This gene may be critical in the development of ovarian cancer. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with EEF1A2

  • eukaryotic translation elongation factor 1 alpha 2 (EEF1A2) antibody
  • eukaryotic translation elongation factor 1 alpha 1 (EEF1A1) antibody
  • eukaryotic translation elongation factor 1 alpha 2 (Eef1a2) antibody
  • eukaryotic translation elongation factor 1 alpha 2 S homeolog (eef1a2.S) antibody
  • eukaryotic translation elongation factor 1 alpha 2 (eef1a2) antibody
  • putative elongation factor 1-alpha-like 3 (LOC739210) antibody
  • eukaryotic translation elongation factor 1 alpha 2 (EEF1) antibody
  • eukaryotic translation elongation factor 1 alpha 2 (eef1) antibody
  • Eef1a antibody
  • EEF1A-2 antibody
  • EEF1A2 antibody
  • eef1al antibody
  • EF-1-alpha-2 antibody
  • ef1a antibody
  • HS1 antibody
  • Ps10 antibody
  • RATPS10 antibody
  • S1 antibody
  • STN antibody
  • stnl antibody
  • wasted antibody
  • wst antibody
  • zgc:92085 antibody

Protein level used designations for EEF1A2

eEF1A-2 , elongation factor 1-alpha 2 , elongation factor-1 alpha , eukaryotic elongation factor 1 A-2 , statin S1 , statin-S1 , elongation factor 1-alpha 1 , eukaryotic translation elongation factor 1 alpha 2 , EF-1-alpha-2 , Statin-like protein , elongation factor 1 A-2 , ef-1-alpha-2 , elongation factor 1 A2 , LOW QUALITY PROTEIN: elongation factor 1-alpha 2

GENE ID SPECIES
1917 Homo sapiens
403506 Canis lupus familiaris
13628 Mus musculus
24799 Rattus norvegicus
380550 Xenopus laevis
419244 Gallus gallus
496898 Xenopus (Silurana) tropicalis
515233 Bos taurus
739210 Pan troglodytes
5727887 Chlamydomonas reinhardtii
9620997 Volvox carteri f. nagariensis
100008677 Oryctolagus cuniculus
100025136 Monodelphis domestica
100549386 Meleagris gallopavo
436644 Danio rerio
100731897 Cavia porcellus
100060464 Equus caballus
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