anti-Fc Receptor-Like 3 (FCRL3) Antibodies

Human Fc Receptor-Like 3 (FCRL3) interaction partners

1. The results indicate that FCRL3 gene polymorphisms are associated with the development and progression of IgA nephropathy (IgAN) in a Chinese Han population, and the rs11264794-A allele showed a protective role for IgAN due to reduced specific binding between miR-183-5p.1 and FCRL3 3'-untranslated region.

2. This study identified novel single nucleotide polymorphism in FCRL3 and FCRL5 significantly associated with the risk for asthma with comorbid allergic rhinitis in the Chinese population

3. FCRL3 -169C allele may increase the risk of developing tendinopathy.

4. no association between the FCRL-3 rs7528684 SNP with susceptibility to allergic asthma in Iranian North-Western Azeri population.

5. -169CC genotype associated with a beneficial functional effect on residual insulin secretion and HbA1c level dynamics in type 1 diabetes

6. Pooled genome wide association study identified a genetic variant upstream of FCRL3 as a susceptibility locus for Graves' disease in addition to those identified in the Major Histo-compatibility Complex.

7. The expression of Sezary signature genes: FCRL3, Tox, and miR-214, was significantly higher in samples from Sezary syndrome patients with CD164 expressing CD4(+) T cells.

8. This study aims to investigate the association between common polymorphisms of FCRL3 gene and multiple sclerosis risk in a Chinese Han population.

9. Observed no association between the MHC2TA or FCRL3 SNPs and rheumatoid arthritis in Mexican patients.

10. genetic polymorphism is associated with rheumatoid arthritis in Chinese Han population

11. Genetic polymorphisms in FCRL3 are genetic risk factors for neuromyelitis optica in the Chinese population.

12. FCRL3_3, FCRL3_5 and FCRL3_6 polymorphisms could increase susceptibility to Graves' disease only in Asians, rather than in Caucasians.

13. CTLA4 and FCRL3 genes overexpression may play an important role in children suffering from autoimmune thyroiditis.

14. FCRL3 genetic polymorphisms were associated with an increased risk of endometriosis-related infertility, regardless of symptoms.

15. 4 Single Nucleotide Polymorphisms (rs7528684, rs945635, rs3761959, and rs2282284) could significantly elevate the risk of Neuromyelitis Optica in Chinese Han population.

16. study found a significant association between the SNPs in FCRL3 gene and allergic rhinitis (AR) in Chinese Han patients; results suggest these gene polymorphisms might be the autoimmunity risk for AR

17. Association between FCRL3 polymorphisms and increased risk of sudden sensorineural hearing loss in a Chinese Han population.

18. the TIGIT/FCRL3 combination allows reliable identification of Helios(+) Treg cells even in highly activated conditions in vitro as well as in PBMCs of autoimmune patients.

19. CONCLUSIONS: Our study demonstrated that the FCRL3 -169T>C polymorphism is not a risk factor of systemic lupus erythematosus in the Polish population, but this polymorphism may contribute to autoantibody production in this disease.

20. the FCRL3 polymorphisms are associated with not only autoimmune diseases including RA, GD, T1D, and other disease under different genetic models, but also different ethnic subgroups.