FCRL3 antibody (PE)

Catalog No. ABIN7505905

The Mouse Monoclonal anti-FCRL3 antibody is suitable to detect FCRL3 in samples from Human. It has been validated for FACS.

Quick Overview for FCRL3 antibody (PE) (ABIN7505905)

Target: FCRL3 (Fc Receptor-Like 3 (FCRL3))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This FCRL3 antibody is conjugated to PE

Application: Flow Cytometry (FACS)

Clone: H5

Product Details anti-FCRL3 Antibody (PE)

Purpose: Anti-Hu CD307c PE

Characteristics: The mouse monoclonal antibody H5 recognizes an epitope within extracellular part of CD307c, a transmembrane glycoprotein expressed mainly on NK cells, and T and B cell subsets.

Purification: Purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. Unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.

Immunogen: DNA-immunization followed by a boost with CD307c transfected cells

Isotype: IgG2b, kappa

Application Details

Application Notes: Flow cytometry: The reagent is designed for analysis of human blood cells using 10 μL reagent / 100 μL of whole blood or 10⁶ cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Do not freeze,Protect from prolonged exposure to light

Storage: 4 °C

Storage Comment: Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.

Target Details for FCRL3

Target: FCRL3 (Fc Receptor-Like 3 (FCRL3))

Alternative Name: CD307c

Background: Fc receptor like 3,CD307c is a type I transmembrane glycoprotein of the Fc receptor family. It contains both ITAM and ITIM motifs in its cytoplasmic domain. CD307c is expressed on the surface of NK cells, and T, Treg, B and plasma cell subsets. It seems to play a role in the regulation of immune response. Defects in CD307c function can result in autoimmune diseases, e.g. rheumatoid arthritis or systemic lupus erythematosus.,FcRL3, IRTA3

Gene ID: 115352

UniProt: Q96P31